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Author:

Iyer, Archana Sriram

Title:

Role of Tec family kinases Itk and Btk in FceRI mediated Mast cell signaling

Graduate Program:

Integrative Biosciences

Keywords:

Mast cells
Itk
Btk
FceRI

File:

Download Archana_Iyer_Final_Dissertation.pdf

Committee Members:

Avery August, Committee Chair/Co-Chair
Margherita Teresa Anna Cantorna, Committee Member
Richard John Frisque, Committee Member
Andrew Thomas Henderson, Committee Member
Robert Paulson, Committee Member
Peter John Hudson, Committee Member

Author:

Subramanian, Aparna

Title:

THE BMP4 STRESS ERYTHROID PATHWAY AND THE KIT RECEPTOR TYROSINE KINASE IN FRIEND VIRUS INDUCED ERYTHROLEUKEMIA

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Friend virus
Erythroleukemia
BMP4
flexed-tail
Kit receptor tyrosine kinase
stress erythropoiesis

File:

Download The_Pennsylvania_State_University.pdf

Committee Members:

Robert Paulson, Committee Chair/Co-Chair
Pamela Hankey Giblin, Committee Member
Avery August, Committee Member
Richard John Frisque, Committee Member
Biao He, Committee Member

Author:

WILSON, CALEPH B

Title:

THE INFLAMMATORY CONTROL VALVE: Modulation of Responses to LPS and IFN-gamma by the RON Receptor Tyrosine Kinase In Vitro and In Vivo

Graduate Program:

Pathobiology

Keywords:

Nitric Oxide
Inflammation
Lipopolysaccharide
Interleukin-12
Interferon-gamma
Receptor Tyrosine Kinase
Macrophage
Innate Immunity
Immunology

File:

Download CBW125_CB_Wilson_PhD_Thesis.pdf

Committee Members:

Pamela Hankey, Committee Chair/Co-Chair
Avery August, Committee Member
Margherita Teresa Anna Cantorna, Committee Member
Wendy Hanna Rose, Committee Member
Robert Paulson, Committee Member
Andrew Thomas Henderson, Committee Member

Author:

Chockalingam, Annapoorani

Title:

GENOMIC AND IMMUNOLOGICAL APPROACHES TO CONTROL GRAM-NEGATIVE INTRAMAMMARY INFECTIONS IN DAIRY CATTLE

Graduate Program:

Animal Science

Keywords:

Mastitis
Gram-negative bacteria
Single-nucleotide-ploymorphism
Bactericidal/permeability increasing protein
LPS-binding
cytokines
innate immune response

File:

Download Anna-thesis-eTD.pdf

Committee Members:

Cindy E Mc Kinney, Committee Chair/Co-Chair
Douglas D Bannerman, Committee Chair/Co-Chair
Guy F Barbato, Committee Member
Kenneth Monrad Weiss, Committee Member
Eric Thomas Harvill, Committee Member
Robert Paulson, Committee Member

Author:

Sharda, Daniel Richard

Title:

INDUCTION OF MACROPHAGE ARGINASE I EXPRESSION BY RON AND THE IMPLICATIONS FOR PROMOTING SYNGENEIC TUMOR GROWTH

Graduate Program:

Pathobiology

Keywords:

macrophage activation
tumorigenesis
arginase
RTK
Ron
MSP
IL-4

File:

Download Dissertation--Daniel_R_Sharda.pdf

Committee Members:

Pamela Hankey Giblin, Dissertation Advisor/Co-Advisor
Pamela Hankey Giblin, Committee Chair/Co-Chair
Robert Paulson, Committee Member
Adam Bleier Glick, Committee Member
K Sandeep Praubu, Committee Member
Yanming Wang, Committee Member

Author:

Bruce, Danny W

Title:

VITAMIN D REGULATES THE DEVELOPMENT AND FUNCTION OF INTESTINAL T CELLS

Graduate Program:

Pathobiology

Keywords:

Vitamin D
Immunlogy
Inflammatory bowel disease
T cells
CD8 alpha alpha

File:

Download Bruce_Dissertation.pdf

Committee Members:

Margherita Teresa Anna Cantorna, Dissertation Advisor/Co-Advisor
Avery August, Committee Member
Margherita Teresa Anna Cantorna, Committee Chair/Co-Chair
Na Xiong, Committee Member
Robert Paulson, Committee Member
Andrea Marie Mastro, Committee Member

Author:

Sermwittayawong, Decha

Title:

MECHANISMS OF THE SAGA COACTIVATOR COMPLEX IN REGULATION OF GENE TRANSCRIPTION

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Gcn5
competition
Spt3
TBP
Spt8
SAGA
bromodomain

File:

Download ThesisMaster_071906c.pdf

Committee Members:

Song Tan, Committee Chair/Co-Chair
Jerry L Workman, Committee Member
Benjamin Franklin Pugh, Committee Member
Joseph C. Reese, Committee Member
Robert Paulson, Committee Member
Juliette T J Lecomte, Committee Member

Author:

Wu, Dai-Chen

Title:

FROM EXPLORING ROLES OF SIGNALS IN STRESS ERYTHROPOIESIS TO IN VITRO EXPANDING STRESS ERYTHROID PROGENITORS THAT ALLEVIATE ANEMIA

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Hedgehog
BMP4
hypoxia
hematopoiesis
erythropoiesis
GDF15
anemia
stem cell

File:

Download DC_Wu_Dissertation_Final_renumbered.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Member
Douglas Cavener, Committee Member
David Scott Gilmour, Committee Member
Pamela Hankey Giblin, Committee Member
Ross Cameron Hardison, Committee Member

Author:

Klipfell, Elizabeth Ann

Title:

IDENTIFICATION AND CHARACTERIZATION OF THE PROTEIN-PROTEIN INTERACTIONS WITH THE BETA-HEAVY-SPECTRIN C-TERMINUS

Graduate Program:

Integrative Biosciences

Keywords:

Beta-Heavy-spectrin
Crumbs complex
spectrin based membrane skeleton
ZA instability
yeast 2-hybrid screen

File:

Download BethThesisFinalNov20_.pdf

Committee Members:

Graham Hugh Thomas, Committee Chair/Co-Chair
David Scott Gilmour, Committee Member
Avery August, Committee Member
Robert Paulson, Committee Member

Author:

Wang, Hao

Title:

Prediction, Validation and Targeted Interference of Erythroid Regulatory Modules

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

regulatory potential
gene regulation
conserved noncoding sequences
transcription factor binding sites

File:

Download HW-Thesis.pdf

Committee Members:

Ross Cameron Hardison, Committee Chair/Co-Chair
Webb Colby Miller, Committee Member
Pamela J Mitchell, Committee Member
Robert Paulson, Committee Member
Anton Nekrutenko, Committee Member

Author:

Perry, John Mark

Title:

The Discovery and Characterization of the BMP4-mediated Stress Erythroid Response to Acute Anemia

Graduate Program:

Integrative Biosciences

Keywords:

stress erythropoiesis
erythropoisis
acute anemia
BMP4

File:

Download PhD_Thesis-JohnMPerry.pdf

Committee Members:

Robert Paulson, Committee Chair/Co-Chair
Pamela Hankey Giblin, Committee Member
Ross Cameron Hardison, Committee Member
Andrew Thomas Henderson, Committee Member
Pamela J Mitchell, Committee Member

Author:

Hu, Jianfang

Title:

ROLE OF TEC FAMILY KINASE ITK IN REGULATING THE DEVELOPMENT OF T CELL SUBSETS

Graduate Program:

Biology

Keywords:

Innate T cell
Memory phenotype T cell
Itk
Tec family kinases
Listeria Monocytogenes
CD4/CD8 lineage commitment

File:

Download Jianfang_dissertation.pdf

Committee Members:

Avery August, Committee Chair/Co-Chair
Biao He, Committee Member
Margherita Teresa Anna Cantorna, Committee Member
Robert Paulson, Committee Member
Na Xiong, Committee Member
Wendy Hanna Rose, Committee Member

Author:

Bussard, Karen Marie

Title:

The Role of Osteoblast-Derived Inflammatory Cytokines in Bone Metastatic Breast Cancer

Graduate Program:

Pathobiology

Keywords:

MIP-2
GRO-alpha
osteoblast
osteoclast
breast cancer
MC3T3-E1
MDA-MB-231W
IL-6
MCP-1
VEGF
KC
IL-8

File:

Download K_Bussard_Ph.D._Thesis_2008.pdf

Committee Members:

Andrea Marie Mastro, Committee Chair/Co-Chair
Robert Paulson, Committee Chair/Co-Chair
Avery August, Committee Member
Pamela Hankey Giblin, Committee Member
Carol V Gay, Committee Member
Andrew Thomas Henderson, Committee Member

Author:

Kocherlakota, Kiranmai S

Title:

Molecular Dissection of Sequence Requirements and Interactions of Sticks-and-Stones

Graduate Program:

Integrative Biosciences

Keywords:

Myoblast
Fusion
Signaling
Sticks-and-Stones
Hibris
Phosphorylation

File:

Download ksk156-Thesis.pdf

Committee Members:

Wendy Hanna Rose, Committee Chair/Co-Chair
Susan M Abmayr, Committee Member
Robert Paulson, Committee Member
Richard W Ordway, Committee Member
Kyung An Han, Committee Member
R Scott Hawley, Committee Member

Author:

Shuman, Laurie Ann

Title:

Interaction of Metastatic Breast Cancer Cells with Osteoblasts

Graduate Program:

Immunology and Infectious Diseases

Keywords:

transcription factor
cytokine
metastasis
osteoblast
Breast cancer

File:

Download ShumanThesis2009.pdf

Committee Members:

Andrea Marie Mastro, Dissertation Advisor/Co-Advisor
Andrea Marie Mastro, Committee Chair/Co-Chair
Adam Bleier Glick, Committee Member
Rosalyn Bryson Irby, Committee Member
Robert Paulson, Committee Member
Danny Welch, Committee Member

Author:

Lenox, L. E.

Title:

The flexed-tail (f) Mutant Mouse: Advancing the Understanding of Expansive Erythropoiesis

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

stress erythropoiesis
extra-medullary erythropoiesis
liver
stress BFU-E
spleen
splicing mutation
Smad5
Madh5
BMP4
flexed-tail
expansive erythropoiesis
acute anemia

File:

Download LENOX-thesis.pdf

Committee Members:

Robert Paulson, Committee Chair/Co-Chair
Avery August, Committee Member
Pamela Hankey Giblin, Committee Member
Ross Cameron Hardison, Committee Member
Andrew Thomas Henderson, Committee Member

Author:

Hao, Li

Title:

Evolution of Natural Killer Cell Receptor Genes

Graduate Program:

Biology

Keywords:

birth-and-death
Natural killer receptors
Evolution
duplication

File:

Download thesis_2006-3-21.pdf

Committee Members:

Masatoshi Nei, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Wojciech Makalowski, Committee Member
Robert Paulson, Committee Member

Author:

Ho, Li-Lun

Title:

MOB as Tumor Suppressor is Activated at the Plasma Membrane to Control Tissue Growth and Organ size in Drosophila

Graduate Program:

Integrative Biosciences

Keywords:

Mats
tumor suppressor
Hippo signaling
organ size control

File:

Download Thesis__Li-Lun_Ho.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Avery August, Committee Member
Douglas Cavener, Committee Member
Richard John Frisque, Committee Member
Aimin Liu, Committee Member
Robert Paulson, Committee Member
Peter John Hudson, Committee Member

Author:

Shi, Lei

Title:

The role of Sf-Stk in stress erythropoiesis

Graduate Program:

Integrative Biosciences

Keywords:

stress erythropoiesis
Sf-Stk
Friend Virus

File:

Download Thesis_Lei_Shi.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
Pamela Hankey, Committee Member
Wendy Hanna Rose, Committee Member
Zhi Chun Lai, Committee Member
Naomi S Altman, Committee Member

Author:

Reviriego Mendoza, Marta Maria

Title:

JC VIRUS LARGE T ANTIGEN INTERACTS WITH THE F-BOX PROTEIN b-TRANSDUCIN REPEAT CONTAINING PROTEIN (bTrCP), THEREBY INFLUENCING VIRAL DNA REPLICATION

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

viral DNA replication
JC virus
proteasome
bTrCP

File:

Download reviriegoMendozaPhDThesis.pdf

Committee Members:

Richard John Frisque, Dissertation Advisor/Co-Advisor
Richard John Frisque, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
Jean Elnora Brenchley, Committee Member
Gary H Perdew, Committee Member
Robert Paulson, Committee Member
Anthony Paul Schmitt, Committee Member

Author:

Menon, Madhu Parameswar

Title:

ROLES FOR AN EPO-RECEPTOR PY343-STAT5 SIGNALING AXIS IN STRESS ERYTHROPOIESIS

Graduate Program:

Integrative Biosciences

Keywords:

stress erythropoiesis
Epo
EpoR
erythropoietin receptor
erythropoietin
EpoR-H
EpoR-HM

File:

Download mmthesis.pdf

Committee Members:

Richard John Frisque, Committee Chair/Co-Chair
Don M Wojchowski, Committee Chair/Co-Chair
Pamela Correll, Committee Member
Robert Paulson, Committee Member
Robert Bruce Mitchell, Committee Member

Author:

Law, Mankit

Title:

A FUNCTIONAL LINK BETWEEN STORE-OPERATED CALCIUM CHANNELS AND THE ACTIN-BINDING PROTEIN DREBRIN IN MAST CELLS REVEALED BY 3,5-BIS-TRIFLUOROMETHYL PYRAZOLE (BTP) COMPOUNDS

Graduate Program:

Immunology and Infectious Diseases

Keywords:

Drebrin
BTP2
mast cell
calcium

File:

Download Dissertation-MLaw.pdf

Committee Members:

Avery August, Dissertation Advisor/Co-Advisor
Avery August, Committee Chair/Co-Chair
Pamela Hankey Giblin, Committee Member
Robert Paulson, Committee Member
Anthony Paul Schmitt, Committee Member
Graham Hugh Thomas, Committee Member

Author:

Ray, Manujendra

Title:

THE RON RECEPTOR TYROSINE KINASE, A NEGATIVE REGULATOR OF INTERFERON-GAMMA AND ENDOTOXIN INDUCED MACROPHAGE ACTIVATION

Graduate Program:

Integrative Biosciences

Keywords:

Receptor Tyrosine Kinase
RON
Lipopolysaccharide
Interferon Gamma
Endotoxic Shock
Inflammation

File:

Download Manujendra_Ray_Dissertation.pdf

Committee Members:

Pamela Hankey Giblin, Committee Chair/Co-Chair
Avery August, Committee Member
Robert Paulson, Committee Member
Margherita Teresa Anna Cantorna, Committee Member
Aimin Liu, Committee Member

Author:

Sahu, Nisebita

Title:

REGULATION OF T HELPER CELL RESPONSES AND ALLERGIC ASTHMA BY TEC KINASES, ITK AND TXK

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Allergic Asthma
Tec kinases
Itk
T helper 2 cells
cytokines
chemokines

File:

Download Sahu_N._Ph.D_Dissertation.pdf

Committee Members:

Avery August, Committee Chair/Co-Chair
Robert Paulson, Committee Member
Andrea Marie Mastro, Committee Member
Wendy Hanna Rose, Committee Member
Pamela Hankey, Committee Member
Dr Biao He, Committee Member
Dr Nadine B Smith, Committee Member

Author:

Harandi, Omid Fasihi

Title:

ANALYSIS OF ERYTHROID RECOVERY FROM BONE MARROW TRANSPLANTATION

Graduate Program:

Genetics

Keywords:

Bone Marrow Transplantation
Red Blood Cell
Anemia

File:

Download PhD_Thesis-Omid_Harandi-Final.pdf

Committee Members:

Robert Paulson, Committee Member
Pamela Hankey Giblin, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
Avery August, Committee Member
Kenneth Monrad Weiss, Committee Member
Andrew Thomas Henderson, Committee Member

Author:

Ahn, Younwook

Title:

MOLECULAR AND GENETIC STUDIES OF TRANSCRIPTION FACTOR AP-2 IN DROSOPHILA APPENDAGE DEVELOPMENT

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Hox proteins
transcriptional regulation
enhancers
gene expression
limb development

File:

Download AhnPhDThesis.pdf

Committee Members:

Richard W Ordway, Committee Member
Robert Paulson, Committee Member
Pamela J Mitchell, Committee Chair/Co-Chair
Wendy Hanna Rose, Committee Member
Graham Hugh Thomas, Committee Member

Author:

Li, Pingxin

Title:

ANALYSIS OF PEPTIDYLARGININE DEIMINASE 4 AND HISTONE CITRULLINATION IN TRANSCRIPTIONAL REGULATION AND INNATE IMMUNITY

Graduate Program:

Genetics

Keywords:

Peptidylarginine Deiminase 4
Histone Citrullination
p53
p21
Histone Deacetylase 2
Neutrophil Extracellular Traps

File:

Download Pingxin_Li_Dissertation.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Yanming Wang, Committee Member
David Scott Gilmour, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Joseph C. Reese, Committee Member
Robert Paulson, Committee Member

Author:

Porayette, Prashanth

Title:

THE BMP4-SMAD5 SIGNALING PATHWAY IS REQUIRED FOR THE RAPID EXPANSION OF ERYTHROID PROGENITORS IN THE EMBRYO

Graduate Program:

Integrative Biosciences

Keywords:

fetal liver
BMP4
Smad5
erythropoiesis

File:

Download Porayette_Dissertation.pdf

Committee Members:

Robert Paulson, Committee Chair/Co-Chair
Avery August, Committee Member
Pamela Hankey, Committee Member
Douglas Cavener, Committee Member
Andrew Thomas Henderson, Committee Member
Peter John Hudson, Committee Member

Author:

Shen, Qiuying

Title:

INVESTIGATION OF THE BRAIN SUBSTRATES OF ANXIOUS DEPRESSION

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

HPA axis
GABA
anxious depression
critical period

File:

Download Qiuying_thesis_0714.pdf

Committee Members:

Bernhard Luscher, Dissertation Advisor/Co-Advisor
Bernhard Luscher, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Wendy Hanna Rose, Committee Member
Debashis Ghosh, Committee Member
Jeffrey Maurice Peters, Committee Member
Robert Paulson, Committee Member

Author:

Qi, Qian

Title:

ROLE OF ITK IN THE DEVELOPMENT OF INNATE T CELLS

Graduate Program:

Immunology and Infectious Diseases

Keywords:

gammadelta T cell
Itk structure
innate T cell
Itk
BiFC assay

File:

Download Graduation_Thesis_Qian_Qi.pdf

Committee Members:

Avery August, Dissertation Advisor/Co-Advisor
Avery August, Committee Chair/Co-Chair
Biao He, Committee Member
Margherita Teresa Anna Cantorna, Committee Member
Pamela Hankey Giblin, Committee Member
Robert Paulson, Committee Member
Zhi Chun Lai, Committee Member

Author:

Gupta, Sounak

Title:

PERK (EIF2AK3) REGULATES PROINSULIN TRAFFICKING AND QUALITY CONTROL IN THE SECRETORY PATHWAY

Graduate Program:

Molecular Medicine

Keywords:

DIABETES
TRAFFICKING
PERK
INSULINOMA
ENDOPLASMIC RETICULUM
PROINSULIN

File:

Download SounakGupta-Thesis-Aug2010.pdf

Committee Members:

Douglas Cavener, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Member
Robert Paulson, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Wendy Hanna Rose, Committee Member
Kouacou Konan, Committee Member

Author:

Murakami, Shoko

Title:

ANALYSES OF THE FUNCTION OF THE PALMITOYL TRANSFERASES GODZ AND SERZ-BETA IN KNOCK-OUT MICE

Graduate Program:

Neuroscience

Keywords:

knock out
trafficking
Neuroligin 2
GABAA receptor
palmitoylation

File:

Download murakami.pdf

Committee Members:

Bernhard Luscher, Dissertation Advisor/Co-Advisor
Bernhard Luscher, Committee Chair/Co-Chair
Richard W Ordway, Committee Member
Robert Paulson, Committee Member
Gong Chen, Committee Member
Erin Elizabeth Sheets, Committee Member

Author:

YU, SANHONG

Title:

The differential requirement for vitamin D and vitamin D receptor in iNKT cell development

Graduate Program:

Immunology and Infectious Diseases

Keywords:

vitamin D
vitamin D receptor
iNKT cells

File:

Download thesis_revised_13.pdf

Committee Members:

Margherita Teresa Anna Cantorna, Dissertation Advisor/Co-Advisor
Margherita Teresa Anna Cantorna, Committee Chair/Co-Chair
Avery August, Committee Member
Robert Paulson, Committee Member
Na Xiong, Committee Member
Terryl Johnson Hartman, Committee Member

Author:

Hao, Shengli

Title:

Regulation of serum response factor activation by the B cell antigen receptor

Graduate Program:

Integrative Biosciences

Keywords:

BCR
NFAT
Ca2+
DAG
actin
IP3R
Lyn
Syk
Btk
PLCg
ERK
BCR signal
SRF

File:

Download Hao_thesis.pdf

Committee Members:

Avery August, Committee Chair/Co-Chair
Robert Paulson, Committee Member
Andrew Thomas Henderson, Committee Member
Pamela Hankey Giblin, Committee Member
Sally Johnson, Committee Member

Author:

He, Shihan

Title:

MECHANISM OF GP55 MEDIATED SF-STK ACTIVATION

Graduate Program:

Pathobiology

Keywords:

erythroid progenitor cell
short form Stk receptor tyrosine kinase
murine erythroleukemia
Friend virus
protein inteaction
cell signaling

File:

Download Shihan_thesis.pdf

Committee Members:

Pamela Hankey Giblin, Dissertation Advisor/Co-Advisor
Pamela Hankey Giblin, Committee Chair/Co-Chair
Avery August, Committee Member
Biao He, Committee Member
Robert Paulson, Committee Member
Zhi Chun Lai, Committee Member

Author:

Ni, Shuang

Title:

A Novel Cell Signaling Pathway In Friend Virus Induced Erythroleukemia

Graduate Program:

Integrative Biosciences

Keywords:

Friend Virus
Stat3
Colony Assay

File:

Download shuang_thesis.pdf

Committee Members:

Pamela Hankey Giblin, Committee Chair/Co-Chair
Robert Paulson, Committee Member
Avery August, Committee Member
Biao He, Committee Member
Richard John Frisque, Committee Member

Author:

Shimizu, Takeshi

Title:

The Drosophila Model of Cancer: Characterization of a Conserved Tumour Suppressor and Its Role in the Control of Cell Proliferation and Apoptosis

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

cancer biology
tumor suppressor
wts
lats
hpo
mats
Drosophila

File:

Download VersionR04.pdf

Committee Members:

Zhi Chun Lai, Committee Chair/Co-Chair
Carol V Gay, Committee Member
Richard W Ordway, Committee Member
Robert Paulson, Committee Member
Wendy Hanna Rose, Committee Member

Author:

Krishnan, Venkatesh

Title:

THREE-DIMENSIONAL OSTEOBLASTIC TISSUE TO STUDY BREAST CANCER COLONIZATION OF BONE

Graduate Program:

Integrative Biosciences

Keywords:

metastasis
bone-remodeling-unit
3D
breast-cancer
osteoclast
osteoblast
colonization of bone

File:

Download Krishnan_Thesis_Dec2011.pdf

Committee Members:

Andrea Marie Mastro, Dissertation Advisor/Co-Advisor
Andrea Marie Mastro, Committee Chair/Co-Chair
Erwin A Vogler, Committee Member
Kumble Sandeep Prabhu, Committee Member
Robert Paulson, Committee Member

Author:

Ye, Xin

Title:

GROWTH CONTROL BY HIPPO AND AKT SIGNALING PATHWAYS IN DROSOPHILA MELANOGASTER

Graduate Program:

Genetics

Keywords:

growth control
Hippo
Akt
Drosophila

File:

Download final_thesis_07272010.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Member
Robert Paulson, Committee Chair/Co-Chair
Richard W Ordway, Committee Member
Wendy Hanna Rose, Committee Member
Yanming Wang, Committee Member

Author:

Wei, Xin

Title:

REGULATION OF RECEPTOR ACTIVITY AND SPECIFICITY: LESSONS LEARNED FROM THE EVOLUTIONARY DIVERGENCE OF HUMAN AND MOUSE RON RECEPTOR TYROSINE KINASES

Graduate Program:

Biochemistry and Molecular Biology

Keywords:

Erk
signaling
receptor tyrosine kinase
Ron
Src
Juxtamembrane domain

File:

Download final-thesis.pdf

Committee Members:

Pamela Hankey Giblin, Committee Chair/Co-Chair
Andrew Thomas Henderson, Committee Member
Avery August, Committee Member
Robert Paulson, Committee Member
John Patrick Vanden Heuvel, Committee Member
Jia Li, Committee Member

Author:

Xu, Xu

Title:

The GCN2 eIF2alpha kinase regulates lipid and glucose homeostasis

Graduate Program:

Cell and Developmental Biology

Keywords:

GCN2
FSP27
Triglyceride Storage
Insig2a
C/EBPbeta
Gluconeogenesis

File:

Download 11282011_Xu_Xu_Ph.D_thesis_final_eTD.pdf

Committee Members:

Douglas Cavener, Dissertation Advisor/Co-Advisor
Gong Chen, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Zhi Chun Lai, Committee Member
Robert Paulson, Committee Member

Author:

Yang, Xi

Title:

Human Microsomal Epoxide Hydrolase (EPHX1): Genetic Polymorphism And Regulation By Chemopreventive Agents

Graduate Program:

Genetics

Keywords:

chemopreventive
Microsomal epoxide hydrolase
polymorphism

File:

Download Thesis_Xi_Yang_v2.CJO.pdf

Committee Members:

Curtis John Omiecinski, Dissertation Advisor/Co-Advisor
Curtis John Omiecinski, Committee Member
Robert Paulson, Committee Chair/Co-Chair
Jeffrey Maurice Peters, Committee Member
Adam Bleier Glick, Committee Member
Joshua D Lambert, Committee Member

Author:

Zhang, Xuqing

Title:

VACCINE-INDUCED-IMMUNITY-MEDIATED COMPETITION BETWEEN ENDEMIC BORDETELLAE AND HOST IMMUNITY AGAINST THEM

Graduate Program:

Genetics

Keywords:

Bordetella
interleukin
sigma factor
vaccine

File:

Download Xuqing_Zhang_dissertation.pdf

Committee Members:

Eric Thomas Harvill, Dissertation Advisor/Co-Advisor
Eric Thomas Harvill, Committee Chair/Co-Chair
Robert Paulson, Committee Chair/Co-Chair
Avery August, Committee Member
Mary J Kennett, Committee Member
Sarah Ellen Ades, Committee Member

Author:

Zhang, Ying

Title:

Distinctive Genomic Features of Erythroid Cis-Regulatory Modules

Graduate Program:

Genetics

Keywords:

Cis-Regulatory Modules
GATA1
ESPERR
Word Enumeration
ChIP

File:

Download Thesis.pdf

Committee Members:

Ross Cameron Hardison, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
Douglas Cavener, Committee Member
Francesca Chiaromonte, Committee Member
Kateryna Dmytrivna Makova, Committee Member

Author:

Cheng, Yong

Title:

MAPPING, CONSERVATION AND FUNCTION OF BINDING SITES FOR ERTHYROID TRANSCRIPTION FACTOR GATA1 IN THE MOUSE GENOME

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

conservation
ChIP-chip
GATA1
function

File:

Download Thesis_yongcheng.pdf

Committee Members:

Ross Cameron Hardison, Dissertation Advisor/Co-Advisor
Ross Cameron Hardison, Committee Chair/Co-Chair
Robert Paulson, Committee Member
Stephan C Schuster, Committee Member
David Scott Gilmour, Committee Member
Reka Z Albert, Committee Member

Author:

Chen, Yu-Chi

Title:

ORGANIC SELENIUM MODIFIES THE OSTEOBLAST INFLAMMATORY STRESS RESPONSE TO BONE METASTATIC BREAST CANCER CELLS IN VITRO AND AFFECTS BREAST CANCER PROGRESSION IN VIVO

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

NF-kappa B
selenium
inflammatoru response
osteoblast
brreast cancer bone metastasis
MDA-MB-231
4T1.2

File:

Download YCC_thesis_2011fall.pdf

Committee Members:

Andrea Marie Mastro, Dissertation Advisor/Co-Advisor
Andrea Marie Mastro, Committee Chair/Co-Chair
Kumble Sandeep Prabhu, Committee Member
Lorraine C Santy, Committee Member
Yanming Wang, Committee Member
Robert Paulson, Committee Member

Author:

LI, YULIN

Title:

The growth retardation and liver dysfunction of PERK knockout mice

Graduate Program:

Genetics

Keywords:

PERK
Liver dysfunction
Steatosis
Wolcott-Rallison syndrome
growth retardation
EIF2AK3

File:

Download Thesis-YULIN--format_review.pdf

Committee Members:

Douglas Cavener, Committee Member
Gong Chen, Committee Member
Bernhard Luscher, Committee Chair/Co-Chair
Richard W Ordway, Committee Member
Robert Paulson, Committee Member

Author:

Gunderson, Andrew Joseph

Title:

The tumor promoting roles of lymphocytes during RAS initiated inflammation and skin carcinogenesis

Graduate Program:

Immunology and Infectious Diseases

Keywords:

tumor immunology
RAS
inflammation
skin cancer
lymphocytes

File:

Download Dissertation_AGunderson_final.pdf

Committee Members:

Adam Bleier Glick, Dissertation Advisor/Co-Advisor
Wendy Hanna Rose, Committee Member
Robert Paulson, Committee Member
Todd Schell, Committee Member
Avery August, Special Member

Author:

Zhou, Kang

Title:

cytoskeletal regulation of gremline architecture in C. elegans

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

C.elegans
germline
cytoskeleton

File:

Download Zhou_Thesis_final.pdf

Committee Members:

Wendy Hanna Rose, Dissertation Advisor/Co-Advisor
Melissa Rolls, Dissertation Advisor/Co-Advisor
Joseph C. Reese, Committee Member
Robert Paulson, Committee Member
Aimin Liu, Committee Member

Author:

Weyrich, Laura Susan

Title:

Respiratory Pathogen Interactions with the Microbiome: The Molecular Mechanisms to the Ethical Implications

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

microflora
Bordetella
respiratory tract
pathogens
COPD
microbiome
whooping cough
probiotics
Type VI Secretion System

File:

Download 4.9.12__Weyrich_-_FINAL_Dissertation_PDF.pdf

Committee Members:

Eric Thomas Harvill, Dissertation Advisor/Co-Advisor
Eric Thomas Harvill, Committee Chair/Co-Chair
Jean Elnora Brenchley, Committee Member
Jesse Ballenger, Special Member
Robert Paulson, Committee Member
Richard John Frisque, Committee Member

Author:

Hester, Sara E

Title:

Bordetella species: Sensing and Evading Host Immunity

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Bordetella species
Sensing the Environment
Immunomodulation
Horizontal Gene Transfer
Host Specificity
Bacterial Pathogen

File:

Download Hester-Dissertation__Final_.pdf

Committee Members:

Eric Thomas Harvill, Dissertation Advisor/Co-Advisor
Sarah Ellen Ades, Committee Member
Robert Paulson, Committee Member
Kathleen Postle, Committee Member
Andrew Fraser Read, Committee Member

Author:

Kumar, Swathi Ashok

Title:

Epigenetic Modulation of Erythroid Expression: An Integrative Stud of Histone Modifications, Transcription Factors and Transcriptomes.

Graduate Program:

Genetics

Keywords:

Epigenetics
erythroid differentiation
multivariate statistics
histone modifications
transcription factors
G1E
G1E-ER4+E2

File:

Download KumarSA_May2012.pdf

Committee Members:

Ross Cameron Hardison, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
David Scott Gilmour, Committee Member
Kateryna Dmytrivna Makova, Committee Member
Francesca Chiaromonte, Special Member

Author:

Vakil, Devashree S

Title:

Autocrine IL-2 Signaling And The Memory CD8+ T Cell Response

Graduate Program:

Genetics

Keywords:

IL-2
Memory CD8 T Cell

File:

Download Thesis.pdf

Committee Members:

Dr Vandana Kalia, Thesis Advisor/Co-Advisor
Dr Surojit Sarkar, Thesis Advisor/Co-Advisor
Robert Paulson, Thesis Advisor/Co-Advisor
Douglas Cavener, Thesis Advisor/Co-Advisor
Jeffrey Maurice Peters, Thesis Advisor/Co-Advisor

Author:

Karanikas, Alexia Theofanie

Title:

INFECTION- AND VACCINATION-INDUCED IMMUNITY AGAINST ENDEMIC BORDETELLA SPECIES

Graduate Program:

Integrative Biosciences

Keywords:

Bordetella
Itk
IL-2
Pertussis toxin
Type VI Secretion System

File:

Download Final_Dissertation.pdf

Committee Members:

Eric Thomas Harvill, Dissertation Advisor/Co-Advisor
Andrew Fraser Read, Committee Member
Margherita Teresa Anna Cantorna, Committee Member
Robert Paulson, Committee Member
Avery August, Special Member

Author:

Chandler, Paige Nicole

Title:

In Vitro Interactions Among Breast Cancer Cells, Osteoblasts and Megakaryocytes

Graduate Program:

Physiology

Keywords:

breast cancer
metastasis
megakaryocytes
osteoblasts
cytokines

File:

Download REVISED_Masters_Thesis_Template_make_revisions_to_this_one_newer_PDF.pdf

Committee Members:

Andrea Marie Mastro, Thesis Advisor/Co-Advisor
Connie Jo Rogers, Thesis Advisor/Co-Advisor
Robert Paulson, Thesis Advisor/Co-Advisor

Author:

Tian, Xi

Title:

The role of zinc in ovarian function

Graduate Program:

Animal Science

Keywords:

zinc
ovary
follicular development
oocyte
embryonic development
mouse

File:

Download Xi_Tian_Final_Dissertation.pdf

Committee Members:

Francisco Javier Diaz, Dissertation Advisor/Co-Advisor
Francisco Javier Diaz, Committee Chair/Co-Chair
Alan Leslie Johnson, Committee Member
Paul Allen Bartell, Committee Member
Robert Paulson, Committee Member
Shannon Leanne Kelleher, Committee Member

Author:

Kim, Dongwon

Title:

Regulatory mechanisms of G protein-coupled receptor (gpcr) signaling at follicle selection in the hen ovary

Graduate Program:

Integrative Biosciences

Keywords:

ovarian follicle
follicle selection
granulosa cell
granulosa cell differentiation
G protein-coupled receptor
follicle stimulating hormone receptor
vasoactive intestinal peptide receptor
beta-arrestin
GPCR kinase2
desensitization
circadian rhythm
angiogenesis
vascular endothelial growth factor
angiopoietin

File:

Download DWK_PhD_dissertation.pdf

Committee Members:

Alan Leslie Johnson, Dissertation Advisor/Co-Advisor
Alan Leslie Johnson, Committee Chair/Co-Chair
Joy Lee Pate, Committee Member
Francisco Javier Diaz, Committee Member
Robert Paulson, Special Member

Author:

Jain, Deepti Prakash

Title:

Genome wide dynamics of GATA1 binding provide insights into the mechanisms of erythroid differentiation

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

GATA1
Next generation sequencing
Quality control
reproducibility
eryhtropoiesis

File:

Download DeeptiJain_dissertation.pdf

Committee Members:

Ross Cameron Hardison, Dissertation Advisor/Co-Advisor
Ross Cameron Hardison, Committee Chair/Co-Chair
Qunhua Li, Committee Member
Robert Paulson, Committee Member
David Scott Gilmour, Committee Member
Benjamin Franklin Pugh, Committee Member

Author:

Li, Yihan

Title:

Methods in Multiple Testing and Meta-analysis with Applications to the Analysis of Genomic Data

Graduate Program:

Statistics

Keywords:

Multiple testing; Meta-analysis; Genomic data analysis; Microarr

File:

Download Yihan_LI_-_Dissertation.pdf

Committee Members:

Debashis Ghosh, Dissertation Advisor/Co-Advisor
Debashis Ghosh, Committee Chair/Co-Chair
Le Bao, Committee Member
Qunhua Li, Committee Member
Robert Paulson, Committee Member

Author:

Mishra, Tejaswini

Title:

Integrative genome-wide studies to elucidate regulation of lineage choice in hematopoiesis

Graduate Program:

Cell and Developmental Biology

Keywords:

hematopoiesis
genomics
gene regulation;RNA-seq;erythroblast;megakaryocyte

File:

Download Dissertation_TejaswiniMishra.pdf

Committee Members:

Ross Cameron Hardison, Dissertation Advisor/Co-Advisor
Michael Axtell, Committee Member
Benjamin Franklin Pugh, Committee Member
Robert Paulson, Committee Member
Debashis Ghosh, Committee Member

Author:

Hegde, Shailaja N

Title:

The Role of Hedgehog,p53 and Yap1 in chronic myelogenous leukemia and Friend vrus erythroleukemia stem cell self renewal

Graduate Program:

Pathobiology

Keywords:

CML
Hedgehog
p53
Yap1
BCR-ABL

File:

Download shailaja_thesis4-7-2.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
Pamela Hankey Giblin, Committee Member
Anthony Paul Schmitt, Committee Member
Wendy Hanna Rose, Committee Member

Author:

Wang, Shu

Title:

Peptidylarginine deiminase inhibitors regulate autophagy of human cancer cells and inflammation response of immune cells

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

PAD inhibitor; cancer epigenetics; ChIP-exo; citrullination; ER

File:

Download Shu_Wang_Dissertation_final.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Yanming Wang, Committee Chair/Co-Chair
Andrea Marie Mastro, Committee Member
David Scott Gilmour, Committee Member
Gong Chen, Committee Member
Robert Paulson, Committee Member

Author:

Yu, Tian

Title:

Integrative analyses of hippo pathway Mutations in human cancer genome

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

mutation
cancer genome
Hippo Pathway
signal transduction
tumor
mutation correlation

File:

Download Tian_Yus_dissertation_Dec_final.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Francisco Javier Diaz, Committee Member
Graham Hugh Thomas, Committee Member
Robert Paulson, Special Member

Author:

Muse, Sarah Jane

Title:

Virulence and Infection: Interactions between Bordetella bronchiseptica and The Immune System

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Bordetella bronchiseptica
secretion system
host-pathogen interactions
inflammasome

File:

Download SJM_Dissertation_in_template__v.15_.pdf

Committee Members:

Eric Thomas Harvill, Dissertation Advisor/Co-Advisor
Andrea Marie Mastro, Committee Member
Robert Paulson, Committee Member
Kumble Sandeep Prabhu, Special Member

Author:

Greischar, Megan A

Title:

Predicting the consequences of diverse life history in malaria parasites: synchrony and transmission investment

Graduate Program:

Entomology

Keywords:

malaria
life history
synchrony
transmission investment
simulation
virulence

File:

Download Greischar-Dissertation.pdf

Committee Members:

Ottar N Bjornstad, Dissertation Advisor/Co-Advisor
Andrew Fraser Read, Dissertation Advisor/Co-Advisor
Jason Laurence Rasgon, Committee Member
Robert Paulson, Committee Member

Author:

Dogan, Nergiz

Title:

Elucidating Biological Function of Genomic DNA with Robust Signals of Biochemical Activity: Integrative Genome-wide Studies of Enhancers

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Functional genomics
Gene regulation
TAL1
GATA1
Histone modifications
Enhancer assay

File:

Download Dogan_PhDThesis_final.pdf

Committee Members:

Ross Cameron Hardison, Dissertation Advisor/Co-Advisor
Ross Cameron Hardison, Committee Chair/Co-Chair
David Scott Gilmour, Committee Member
Robert Paulson, Committee Member
Philip L Reno, Committee Member
Anton Nekrutenko, Committee Member

Author:

Xiang, Jie

Title:

REGULATION OF STRESS ERYTHROPOIESIS: INTERACTION BETWEEN MICROENVIRONMENT AND STRESS ERYTHROID PROGENITORS

Graduate Program:

Integrative Biosciences

Keywords:

Stress erythropoiesis
Stem cell
Epo
progenitors
Anemia

File:

Download Jie_Xiang-Phd_Thesis-_final_updated.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
Zhi Chun Lai, Committee Member
Kumble Sandeep Prabhu, Committee Member
Yanming Wang, Committee Member
Naomi S Altman, Committee Member

Author:

Liu, Jinling

Title:

Genetic analyses of the cilia-dependent hedgehog signal transduction in the mouse

Graduate Program:

Biology

Keywords:

hedgehog
spinal cord patterning
Gli
Sufu
cilia

File:

Download Jinling_Liu_Dissertation_Dec_2_Final.pdf

Committee Members:

Aimin Liu, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Robert Paulson, Committee Member

Author:

Sun, Weina

Title:

Henipavirus assembly and budding

Graduate Program:

Pathobiology

Keywords:

Henipavirus
Hendra virus
Nipah virus
assembly and budding
paramyxovirus
AP-3 complex
Hendra virus fusion protein
Rab11a

File:

Download Weina_Sun_Doctoral_Dissertation.pdf

Committee Members:

Anthony Paul Schmitt, Dissertation Advisor/Co-Advisor
Anthony Paul Schmitt, Committee Chair/Co-Chair
Robert Paulson, Committee Member
Kumble Sandeep Prabhu, Committee Member
Pamela Hankey Giblin, Committee Member
Craig Eugene Cameron, Committee Member

Author:

Jackson, Walter

Title:

The Role of Megakaryocytes in Breast Cancer Metastasis to Bone.

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

Breast Cancer
Megakaryocytes
Bone metastasis
Thrombopoietin
Stromal derived factor-1
Platelets
Extramedullary Hematopoiesis

File:

Download Walter_Jackson_Final_Thesis.pdf

Committee Members:

Andrea Marie Mastro, Dissertation Advisor/Co-Advisor
Andrea Marie Mastro, Committee Chair/Co-Chair
Pamela Hankey Giblin, Committee Member
Mary J Kennett, Committee Member
Robert Paulson, Committee Member
Henry Joseph Donahue, Special Member
Melissa Rolls, Committee Member

Author:

Bendor, Liron

Title:

Novel Mechanisms of Bordetella Survival in the Mammalian Host and in the Environment

Graduate Program:

Genetics

Keywords:

Bordetella
bordetella bronchiseptica
amoeba
dictyostelium
amoeba
Type Six Secretion System
intracellular survival

File:

Download THESIS_LIRON_BENDOR.pdf

Committee Members:

Eric Thomas Harvill, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
Kenneth Charles Keiler, Committee Member
Mary J Kennett, Committee Member
Ross Cameron Hardison, Committee Member

Author:

Zhang, Yifan

Title:

INVESTIGATION OF FUNCTION AND REGULATORY MECHANISM OF GENES CONTROLLING TISSUE GROWTH IN DROSOPHILA MELANOGASTER

Graduate Program:

Genetics

Keywords:

growth control
cell apoptosis
ER stress
JNK signaling
Hippo signaling

File:

Download Yifan_Zhang_dissertation.pdf

Committee Members:

Zhi-Chun Lai, Dissertation Advisor/Co-Advisor
Yanming Wang, Committee Chair/Co-Chair
Robert Paulson, Committee Member
Richard W Ordway, Committee Member
Wendy Hanna-Rose, Outside Member

Author:

Hariharan, Sneha

Title:

STUDY OF GROWTH OF STRESS ERYTHROID PROGENITORS FROM PERIPHERAL BLOOD MONONUCLEAR CELLS IN MURINE AND HUMAN ANEMIC MODEL SYSTEMS.

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

Stress erythropoiesis
erythroid progenitor migration
Sickle cell disease
acute anemia

File:

Download Sneha_Masters_Thesis_2016.pdf

Committee Members:

Robert Paulson, Thesis Advisor/Co-Advisor
K. Sandeep Prabhu, Committee Member
Pamela A. Hankey, Committee Member

Author:

sun, jinquan

Title:

A NOVEL SMALL MOLECULE DNA INTERCALATOR PZ1225 IN CANCER CELL APOPTOSIS AND A HISTONE MODIFIER PAD4 IN MACROPHAGE EXTRACELLULAR TRAP FORMATION

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

DNA damage
DNA intercalator
small molecule
MAPK
mTOR
apoptosis
macrophage
extracellular traps
PAD4
citrullination
stroke

File:

Download Graduation_Thesis-Jinquan-20161201.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Zhi-Chun Lai, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Lu Bai, Committee Member
Robert Paulson, Outside Member

Author:

Smith, Kayla Jo

Title:

THE ROLE OF THE ARYL HYDROCARBON RECEPTOR IN MODULATING SKIN AND INTESTINAL EPITHELIAL PHYSIOLOGY

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

aryl hydrocarbon receptor
skin
intestine
inflammation
keratinocyte

File:

Download Smith_Kayla_J_Dissertation_2017_Final.pdf

Committee Members:

Gary Perdew, Dissertation Advisor/Co-Advisor
Gary Perdew, Committee Chair/Co-Chair
Jeffrey Peters, Committee Member
Robert Paulson, Committee Member
Edward Dudley, Outside Member
Richard Frisque, Committee Member

Author:

Bennett, Laura F

Title:

Analysis of Stress Erythropoiesis: Stimulation of Toll-Like Receptors Induces Erythrophagocytosis and Activates Stress Erythropoiesis

Graduate Program:

Genetics

Keywords:

Stress erythropoiesis
inflammation
erythrophagocytosis
heme
anemia
pro-inflammatory cytokines

File:

Download LF_Bennett_Dissertation_Aug_2017_FINAL.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Pamela Hankey Giblin, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
Zhi-Chun Lai, Committee Member
Kumble Sandeep Prabhu, Outside Member
Connie Jo Rogers, Committee Member

Author:

Munoz, Elyse Elaine

Title:

Cue the stress: Malaria parasites employ canonical and novel stress granules as a developmental mechanism

Graduate Program:

Genetics

Keywords:

Malaria
Plasmodium yoelii
Plasmodium
stress response
ALBA4

File:

Download 20200125_EM_Dissertation.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Manuel Llinas, Committee Chair/Co-Chair
Andrew David Patterson, Committee Member
David Scott Gilmour, Committee Member
David Scott Gilmour, Outside Member
Robert Paulson, Program Head/Chair

Author:

Allen, Joselyn Natasha

Title:

THE NON-ALCOHOLIC STEATOHEPATITIS SPECTRUM AND ASSOCIATED METABOLIC RISK FACTORS: THE EFFECTS OF IMPAIRED RON RECEPTOR SIGNALING IN DIET-INDUCED APOLIPOPROTEIN E-DEFICIENT MURINE MODELS

Graduate Program:

Immunology and Infectious Diseases

Keywords:

Ron receptor tyrosine kinase
Macrophage stimulating protein
Non-alcoholic steatohepatitis
Hepatic fibrosis
Inflammation

File:

Download Joselyn_Allen__Dissertation_FINAL.pdf

Committee Members:

Pamela Hankey Giblin, Dissertation Advisor/Co-Advisor
Pamela Hankey Giblin, Committee Chair/Co-Chair
Andrew David Patterson, Committee Member
Na Xiong, Committee Member
Joshua D Lambert, Outside Member
Robert Paulson, Committee Member

Author:

Liao, Chang

Title:

REGULATION OF STRESS ERYTHROPOIESIS AND THE NICHE: A NOVAL ROLE OF SELENOPROTEINS

Graduate Program:

Pathobiology

Keywords:

Selenoproteins
Stress erythropoiesis
Erythropoietic nice

File:

Download Thesis_CL2018_revision.pdf

Committee Members:

K. Sandeep Prabhu, Dissertation Advisor/Co-Advisor
K. Sandeep Prabhu, Committee Chair/Co-Chair
Robert Paulson, Committee Member
Pamela Hankey Giblin, Committee Member
Qunhua Lia, Outside Member

Author:

Shi, Lai

Title:

PAD4 MEDIATED CANCER EXTRACELLULAR CHROMATIN NETWORK IN BREAST CANCER PROMOTES THE DEVELOPMENT AND PROGRESSION OF LUNG METASTASIS

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

PAD4
Hypercitrullination
Cancer Extracellular Chromatin Network
Breast cancer
Lung metastasis

File:

Download Dissertation-Lai_Shi.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Yong Wang, Committee Chair/Co-Chair
Siyang Zheng, Committee Member
Yanming Wang, Committee Member
Robert Paulson, Outside Member

Author:

Ghanem, Kahina

Title:

AN INTEGRATIVE APPROACH TO INVESTIGATING OVARIAN FOLLICLE DEVELOPMENT AND CYCLIC RECRUITMENT IN CHICKENS

Graduate Program:

Integrative and Biomedical Physiology

Keywords:

Ovary
chicken
follicle
FSH
Relaxin-3
Development
Granulosa cells
Cyclic recruitment

File:

Download 2-27-19_Dissertation_Kahina_Ghanem_2019.pdf

Committee Members:

Alan L. Johnson, Dissertation Advisor/Co-Advisor
Alan L. Johnson, Committee Chair/Co-Chair
Joy L. Pate, Committee Member
Ramesh Ramachandran, Committee Member
Robert Paulson, Outside Member

Author:

Chen, Yuanting

Title:

NOVEL SIGNALS IN STRESS ERYTHROPOIESIS: COORDINATED CONTROL OF WNT, PGE2 AND PERK SIGNALING PATHWAYS REGULATES EXPANSION AND DIFFERENTIATION OF STRESS ERYTHROID PROGENITORS

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

Stress erythropoiesis
Wnt
PGE2
PERK
mTORC1

File:

Download Thesis_2nd_Yuanting_Chen.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
Kumble Sandeep Prabhu, Committee Member
Zhi-Chun Lai, Committee Member
Xiaojun Lance Lian, Outside Member
Wendy Hanna-Rose, Committee Member
Melissa Rolls, Program Head/Chair

Author:

Chen, Di

Title:

Genome Architecture and Evolution Shaped by Transposable Elements

Graduate Program:

Genetics

Keywords:

Transposable Elements
L1
Functional Data Analysis
Genome Evolution
Genetics

File:

Download Di_Chen_Genetics_Dissertation_Final_Dec18_2020.pdf

Committee Members:

Mark Shriver, Dissertation Advisor/Co-Advisor
Ross Cameron Hardison, Committee Chair/Co-Chair
Stephen Wade Schaeffer, Committee Member
Robert Paulson, Outside Member
Robert Paulson, Program Head/Chair

Author:

Ravichandran, Abirami

Title:

Characterization of tumor growth, immune and metastatic outcomes in the 4T1.2-HER2 mammary tumor model

Graduate Program:

Integrative and Biomedical Physiology (MS)

Keywords:

mouse mammary tumor model
triple-negative breast cancer
breast cancer
immune response
antigen-specific immune response
tumor immunology

File:

Download aur1121_Thesis_for_submission.pdf

Committee Members:

Connie Jo Rogers, Thesis Advisor/Co-Advisor
Margherita Teresa-Anna Cantorna, Committee Member
Donna Korzick, Program Head/Chair
Robert Paulson, Committee Member

Author:

Johnston, Alexis

Title:

The Effect of Vitamin D Deficiency on Vitamin D Receptor Expression in a VDR/Cre Reporter Mouse and the Effect of Vitamin D on Survival and Natural Killer Cells in Influenza A Infection

Graduate Program:

Pathobiology (MS)

Keywords:

vitamin d
natural killer cell
nk cell
influenza
vdr
cyp27b1

File:

Download Johnston_Vitamin_D_VDRCre_Influenza_NK_Cells.pdf

Committee Members:

Margherita Teresa-Anna Cantorna, Thesis Advisor/Co-Advisor
Vishal Singh, Committee Member
Kumble Prabhu, Program Head/Chair
Robert Paulson, Committee Member
Troy Clavell Sutton, Committee Member

Author:

Ruan, Baiye

Title:

Metabolic and Immunomodulatory Control of Stress Erythroid Progenitors Ensures Effective Erythroid Regeneration

Graduate Program:

Pathobiology (PHD)

Keywords:

stress erythropoiesis
inflammation
metabolism
nitric oxide
itaconate
immunomodulatory

File:

Login to Download

Committee Members:

Andrew Patterson, Major Field Member
Robert Paulson, Chair & Dissertation Advisor
Xiaojun Lian, Outside Unit & Field Member
Kumble Prabhu, Major Field Member
Anthony Schmitt, Professor in Charge/Director of Graduate Studies

Author:

Arora, Juhi

Title:

Vitamin D and the Vitamin D Receptor regulate development and function of the immune system

Graduate Program:

Pathobiology (PHD)

Keywords:

vitamin D
influenza
immunity
hematopoiesis

File:

Login to Download

Committee Members:

Robert Paulson, Major Field Member
Connie Rogers, Outside Unit & Field Member
Margherita Cantorna, Chair & Dissertation Advisor
Anthony Paul Schmitt, Professor in Charge/Director of Graduate Studies
Troy Sutton, Major Field Member

Author:

Qian, Fenghua

Title:

investigation of cyclopentenone prostaglandins and associated receptor GPR44 in acute myeloid leukemia

Graduate Program:

Pathobiology (PHD)

Keywords:

leukemia
selenium
cyclopentenone prostaglandin
crth2
DP2
PPARγ
interleukin-4
androgen receptor
EPHA7
RTK
tumor microenvironment
leukemic stem cell

File:

No files available due to restrictions.

Committee Members:

Robert Paulson, Major Field Member
Kumble Prabhu, Chair & Dissertation Advisor
John Vanden Heuvel, Major Field Member
Anthony Paul Schmitt, Professor in Charge/Director of Graduate Studies
Vishal Singh, Outside Unit & Field Member

Author:

Gandhi, Ujjawal Hitendra

Title:

The Role of Arachidonic Acid - Cyclooxygenase Pathway in the Anti-leukemic Properties of Selenium

Graduate Program:

Molecular Toxicology

Keywords:

Selenium
leukemia
15d-prostaglandin J2
gambogic acid
arachidonic acid
inflammation
leukemia stem cell
BCR-ABL
H-PGDS

File:

Download UHG_Thesis_FINAL.pdf

Committee Members:

Kumble Sandeep Prabhu, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Member
Dr Jack Vanden Heuvel, Committee Member
Shantu G Amin, Committee Member
Dr Ramesh Ramachandran, Committee Member

Author:

Sabahat Gazal, Fnu

Title:

Elucidating the role of host factors in henipavirus budding

Graduate Program:

Pathobiology (PHD)

Keywords:

Henipavirus
ESCRT
angiomotins
Nedd4L
VLPs

File:

Download Final_diss_SG.pdf

Committee Members:

Anthony Schmitt, Chair & Dissertation Advisor
Robert Paulson, Major Field Member
Troy Sutton, Major Field Member
Joyce Jose, Outside Unit & Field Member
Anthony Schmitt, Program Head/Chair