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Author:

Saengwilai, Patompong

Title:

Root traits for efficient nitrogen acquisition and genome-wide association study of root anatomical traits in maize (zea mays L.)

Graduate Program:

Plant Biology

Keywords:

roots
anatomy
nitrogen
agriculture
aerenchyma
root hairs
crown roots
GWAS
QTL
SNP
genetics

File:

Download Saengwilai_Ph.D.thesis.pdf

Committee Members:

Jonathan Paul Lynch, Dissertation Advisor/Co-Advisor
Kathleen Marie Brown, Committee Chair/Co-Chair
Dawn S Luthe, Committee Member
Surinder Chopra, Special Member

Author:

Hua, Wen-yu

Title:

Kernel Methods for Neuroimaging Genomewide Association Studies

Graduate Program:

Statistics

Keywords:

Kernel methods
GWAS
Neuroimaging analysis; Multiple comparison procedures.

File:

Download WenYu-dissertation.pdf

Committee Members:

Debashis Ghosh, Dissertation Advisor/Co-Advisor
Debashis Ghosh, Committee Chair/Co-Chair
Yu Zhang, Committee Member
Qunhua Li, Committee Member
Le Bao, Committee Member
Daniel Kifer, Special Member

Author:

Schill, Thomas Michael

Title:

An Exploration of the Function-on-scalar Lasso

Graduate Program:

Statistics

Keywords:

variable selection
LASSO
FS-LASSO
GWAS
functional linear models
Framingham heart study

File:

Download ThomasSchill-Thesis_final2.pdf

Committee Members:

Matthew Logan Reimherr, Thesis Advisor/Co-Advisor

Author:

Verma, Shefali Setia

Title:

INVESTIGATING COMPUTATIONAL METHODS TO MODEL THE GENOTYPIC AND PHENOTYPIC COMPLEXITY OF ADVERSE HEALTH OUTCOMES: UNDERSTANDING UNDERCOVER HERITABILITY

Graduate Program:

Integrative Biosciences

Keywords:

Association Studies
GWAS
Rare Variants
Common Variants
Epistasis
Genetic Etiology
Complex Traits
Heritability

File:

Download Shefali_Thesis_Revised_FinalETDVersion.pdf

Committee Members:

Marylyn Deriggi Ritchie, Dissertation Advisor/Co-Advisor
Shaun A Mahony, Committee Chair/Co-Chair
Stephen Wade Schaeffer, Committee Member
Cooduvalli S Shashikant, Committee Member
William S. Bush, Outside Member

Author:

Verma, Anurag

Title:

PheWAS AND BEYOND: APPROACHES TO ADDRESS CHALLENGES FOR IDENTIFYING ROBUST ASSOCIATIONS USING CLINICAL DATA

Graduate Program:

Integrative Biosciences

Keywords:

PheWAS
EHR
GWAS
Genomics
Biobank

File:

Download VermaA_Thesis_Submission_03292018.pdf

Committee Members:

Marylyn Ritchie, Dissertation Advisor/Co-Advisor
Moriah Louise Szpara, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
N/A, Committee Member
Yu Zhang, Outside Member

Author:

Elango, Dinakaran

Title:

GENETIC DIVERSITY AND GENOME WIDE MAPPING OF STRESS INDUCED SECONDARY METABOLITES IN SORGHUM (Sorghum bicolor (L.) Moench)

Graduate Program:

Agronomy

Keywords:

GWAS
Sorghum anthracnose
Frost stress
Epi-cuticular wax
Brown mid-rib
Forage sorghum yield and quality
Flavonoid secondary metabolite
3-deoxyanthocyanidin
Anti-oxidant activity

File:

Download eTD-Dinakaran_Elango-991217258.pdf

Committee Members:

Surinder Chopra, Dissertation Advisor/Co-Advisor
Gregory Wayne Roth, Committee Chair/Co-Chair
Majid R Foolad, Committee Member
Lavanya Reddivari, Committee Member
Yinong Yang, Outside Member
Surinder Chopra, Committee Chair/Co-Chair

Author:

White, Julie

Title:

Investigations into the genetic architecture of the human face

Graduate Program:

Anthropology

Keywords:

geometric morphometrics
GWAS
facial genetics
facial asymmetry
3D imaging

File:

Download FigureS11_AllMultiPeakLoci.pdfDownload TableS1_PreviousGWASHits.xlsxDownload TableS3_SuggestiveHits.zipDownload TableS4_203LeadSNPs.xlsxDownload TableS5_MultiPeakLoci.xlsxDownload TableS6_MultiEffectSNPs.xlsxDownload TableS7_ModelEstimatesAfterRefinement.xlsxDownload White_Dissertation.pdf

Committee Members:

Mark Shriver, Dissertation Advisor/Co-Advisor
Mark Shriver, Committee Chair/Co-Chair
George H Perry, Committee Member
Joan Therese Richtsmeier, Committee Member
Hannah M.C. Schreier, Outside Member
Mary Katherine Shenk, Program Head/Chair

Author:

Yang, Lina

Title:

Leveraging Big Genetic Data for Prediction in Multi-ethnic Studies: Applications to Tobacco Use Phenotypes

Graduate Program:

Biostatistics (PHD)

Keywords:

GWAS
meta-analysis
linkage disequilibrium
polygenic risk score
multi-ethnic population
tobacco usage

File:

Download Lina_Yang_dissertation.pdf

Committee Members:

Dajiang Liu, Co-Chair & Dissertation Advisor
Vernon Chinchilli, Co-Chair of Committee
David Mauger, Major Field Member
Bibo Jiang, Outside Field Member
Ian Paul, Outside Unit Member
Arthur Berg, Professor in Charge/Director of Graduate Studies

Author:

Van Kampen, James

Title:

Beyond GWAS: Investigations of Accessory Methodologies to Improve Biological Interpretability

Graduate Program:

Neuroscience

Keywords:

Addiction
Smoking
Genetics
GWAS

File:

Download Thesis_Final_AllChanges_3.22.21.pdf

Committee Members:

Dajiang Liu, Dissertation Advisor/Co-Advisor
Dajiang Liu, Committee Chair/Co-Chair
Andras Hajnal, Committee Member
James Riley Broach, Outside Member
Kent Eugene Vrana, Committee Member
Alistair J Barber, Program Head/Chair

Author:

Zhou, Jiayan

Title:

Towards precision public health: Building novel methods for utilizing formal and informal data

Graduate Program:

Pathobiology (PHD)

Keywords:

precision public health
GWAS
EDGE
phenome-wide gene-gene interactions
epistasis
EWAS
environment-environment interactions
knowledge-based filtering
social media
COVID-19
vaccine acceptance index
complex traits
common diseases

File:

Login to Download

Committee Members:

Kumble Prabhu, Program Head/Chair
Qunhua Li, Outside Field Member
Yifei Huang, Outside Unit Member
Shefali Setia Verma, Special Member
Molly Hall, Chair & Dissertation Advisor
Kumble Prabhu, Major Field Member

Author:

Cheng, Yuhuan

Title:

Trans-Ethnic Meta-Analysis on Lipid Exome Sequencing Data

Graduate Program:

Bioinformatics and Genomics

Keywords:

GWAS
trans-ethnic
meta-analysis
lipids
cardiovascular disease
rare variant
whole-exome sequence

File:

Download FinalThesis.pdf

Committee Members:

Dajiang Liu, Thesis Advisor/Co-Advisor
George H Perry, Program Head/Chair
Laura Carrel, Committee Member
Duanping Liao, Committee Member

Author:

Gonzalez Zarzar, Tomas Benjamin

Title:

An investigation on the evolution and genetics of face shape sex differences, and the ethical issues of sex/gender-inclusionary policies

Graduate Program:

Anthropology

Keywords:

face shape
sex differences
sexual dimorphism
bioeconomy
primitive accumulation
intellectual property rights
facial genetics
GWAS
geometric morphometrics

File:

Download Gonzalez-Dissertation.pdf

Committee Members:

Mark Shriver, Dissertation Advisor/Co-Advisor
Mark Shriver, Committee Chair/Co-Chair
Joan Therese Richtsmeier, Committee Member
David Andrew Puts, Committee Member
Eduardo Mendieta, Outside Member
Eduardo Mendieta, Committee Chair/Co-Chair
Mary Katherine Shenk, Program Head/Chair

Author:

Jiang, Yu

Title:

STATISTICAL METHODS FOR SOLVING PRACTICAL ISSUES IN METAANALYSIS OF GENETIC ASSOCIATION STUDIES OF SEQUENCE DATA

Graduate Program:

Biostatistics

Keywords:

GWAS
meta-analysis
conditional analysis
missing data
multi-allelic variants
tobacco and alcohol addictions.
tobacco and alcohol addictions

File:

Download dissertation.pdfDownload supporting_materials.zip

Committee Members:

Dajiang Liu, Dissertation Advisor/Co-Advisor
Dajiang Liu, Committee Chair/Co-Chair
Vernon M. Chinchilli, Committee Member
Rongling Wu, Committee Member
Patricia Sue Grigson Kennedy, Outside Member
Joshua Ethan Muscat, Committee Member
Arthur Steven Berg, Program Head/Chair

Author:

Wang, Xingyan

Title:

Statistical Methods for Aggregating Trans-Ancestry Genome Wide Association Summary Statistics & Its Applications to Nicotine & Alcohol Addiction Phenotypes

Graduate Program:

Biostatistics (PHD)

Keywords:

Trans-Ancestry
Meta-Analysis
GWAS
Smoking and Drinking addiction
Admixed Population
Fine-mapping
TWAS
Gene Set Enrichment Analysis

File:

No files available due to restrictions.

Committee Members:

Dajiang Liu, Chair & Dissertation Advisor
Jennifer Nyland, Outside Unit Member
Vernon Chinchilli, Major Field Member
Joshua Muscat, Outside Field Member
Rongling Wu, Major Field Member
Arthur Berg, Professor in Charge/Director of Graduate Studies

Author:

McGuire, Daniel

Title:

Methods for assessing replicability in GWAS and analyzing large-scale Electronic Health Record datasets.

Graduate Program:

Biostatistics (PHD)

Keywords:

replicability
GWAMA
GWAS
EHR
mixed-model
mixture-model
spatial random effects
pollution
PheWAS
heritability
family study
meta-analysis
variance components
two-level mixture model
random effects

File:

Download DanMcGuire_dissertation2.pdf

Committee Members:

Arthur Berg, Program Head/Chair
Dajiang Liu, Chair & Dissertation Advisor
Qunhua Li, Outside Unit Member
Arthur Berg, Major Field Member
John Elfar, Outside Field Member