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Author:

Hall, Molly Ann

Title:

Beyond genome-wide association studies (GWAS): Emerging methods for investigating complex associations for common traits

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

gene-gene interactions
epistasis
PheWAS
phenome
EWAS
exposome
gene-environment interactions
complex traits

File:

Download Dissertation_MollyHall.pdf

Committee Members:

Marylyn Deriggi Ritchie, Dissertation Advisor/Co-Advisor
Marylyn Deriggi Ritchie, Committee Chair/Co-Chair
Santhosh Girirajan, Committee Chair/Co-Chair
Scott Brian Selleck, Committee Member
Ross Cameron Hardison, Committee Member
George H Perry, Committee Member
Catherine Mc Carty, Special Member

Author:

Verma, Anurag

Title:

PheWAS AND BEYOND: APPROACHES TO ADDRESS CHALLENGES FOR IDENTIFYING ROBUST ASSOCIATIONS USING CLINICAL DATA

Graduate Program:

Integrative Biosciences

Keywords:

PheWAS
EHR
GWAS
Genomics
Biobank

File:

Download VermaA_Thesis_Submission_03292018.pdf

Committee Members:

Marylyn Ritchie, Dissertation Advisor/Co-Advisor
Moriah Louise Szpara, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
N/A, Committee Member
Yu Zhang, Outside Member

Author:

McGuire, Daniel

Title:

Methods for assessing replicability in GWAS and analyzing large-scale Electronic Health Record datasets.

Graduate Program:

Biostatistics (PHD)

Keywords:

replicability
GWAMA
GWAS
EHR
mixed-model
mixture-model
spatial random effects
pollution
PheWAS
heritability
family study
meta-analysis
variance components
two-level mixture model
random effects

File:

Download DanMcGuire_dissertation2.pdf

Committee Members:

Arthur Berg, Program Head/Chair
Dajiang Liu, Chair & Dissertation Advisor
Qunhua Li, Outside Unit Member
Arthur Berg, Major Field Member
John Elfar, Outside Field Member