1. Biochemical Characterization of Dengue Non-structural Protein 5 (NS5) and General Acid Derivatives Open Access Author: Lugo, Alex J. Title: Biochemical Characterization of Dengue Non-structural Protein 5 (NS5) and General Acid Derivatives Graduate Program: Molecular Medicine Keywords: Dengue NS5RNA-dependent RNA polymeraseEnzyme Kinetics File: Download Alex_Lugo-Thesis.pdf Committee Members: Craig Eugene Cameron, Thesis Advisor/Co-AdvisorCraig Eugene Cameron, Thesis Advisor/Co-Advisor
2. Mechanistic Analysis of the Radical SAM Methylases RlmN and Cfr Open Access Author: Bauerle, Matthew Richard Title: Mechanistic Analysis of the Radical SAM Methylases RlmN and Cfr Graduate Program: Chemistry Keywords: Radical SAM enzymeMechanistic EnzymologyX-ray CrystallographyRlmN and CfrMass SpectrometryElectron Paramagnetic Resonance (EPR) spectroscopyEnzyme KineticsRapid Chemical QuenchpH-rate profileDeuterium ExchangeDirected EvolutionMethylationThiyl RadicalCysteineIron-Sulfur ClusterS-adenosylmethionine5'-deoxyadenosineS-adenosylhomocysteineRadical SAM methylase File: Download Bauerle_Thesis_Final.pdf Committee Members: Dr. Squire J. Booker, Dissertation Advisor/Co-AdvisorDr. Squire J. Booker, Committee Chair/Co-ChairDr. Amie K. Boal, Committee MemberDr. J. Martin Bollinger, Committee MemberDr. William Hancock, Outside MemberDr. Carsten Krebs, Committee Member
