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Open Access

Author:: Burgard, Anthony P.
Title:: OPTIMIZATION-BASED FRAMEWORKS FOR THE ANALYSIS AND REDESIGN OF METABOLIC NETWORKS
Graduate Program:: Chemical Engineering
Keywords:: metabolic network
stoichiometric modeling
microbial strain design
File:: Download Thesis_Complete.pdf
Committee Members:: Costas D Maranas, Committee Chair/Co-Chair
Andrew Zydney, Committee Member
Darrell Velegol, Committee Member
Reka Z Albert, Committee Member

Open Access

Author:: Lehmann, Andreas
Title:: Molecular Design in Chemical and Biological Systems
Graduate Program:: Chemical Engineering
Keywords:: quantum chemistry
molecular design
protein design
protein engineering
File:: Download andreas_thesis.pdf
Committee Members:: Costas D Maranas, Committee Chair/Co-Chair
Margaret K Duda, Committee Member
Kristen Ann Fichthorn, Committee Member
Barbara Jane Garrison, Committee Member

Open Access

Author:: Varshney, Amit
Title:: Optimization and control of multiscale process systems using model reduction: Application to thin-film growth
Graduate Program:: Chemical Engineering
Keywords:: Carleman Linearization
System Identification
Optimization
Dynamic Optimization
Modeling
Multiscale
Stochastic
Model Predictive Control
Receding Horizon Control
Thin film growth
Epitaxy
File:: Download mythesis.pdf
Committee Members:: Antonios Armaou, Committee Chair/Co-Chair
Costas D Maranas, Committee Member
Ali Borhan, Committee Member
Joan Marie Redwing, Committee Member
Andrew Zydney, Committee Member

Open Access

Author:: Vital-Lopez, Francisco Gamaliel
Title:: DEVELOPMENT OF HYBRID INTRACELLULAR/EXTRACELLULAR MODELS OF BRAIN TUMOR PROGRESSION AND MEDICATION STRATEGIES
Graduate Program:: Chemical Engineering
Keywords:: Modeling
Brain tumor
Angiogenesis
Temozolomide
Chemotaxis
Simulation
File:: Download Vital-Lopez_Dissertation.pdf
Committee Members:: Antonios Armaou, Dissertation Advisor/Co-Advisor
Antonios Armaou, Committee Chair/Co-Chair
Costas D Maranas, Committee Chair/Co-Chair
Ali Borhan, Committee Member
Patrick Cirino, Committee Member
Christine Dolan Keating, Committee Member
Andrew Zydney, Committee Member

Open Access

Author:: Khoury, George Adeeb
Title:: COMPUTATIONAL DESIGN TO SWITCH PROTEIN COFACTOR SPECIFICITY AND CREATE ENZYMATIC ACTIVITY
Graduate Program:: Chemical Engineering
Keywords:: evolution
protein design
protein engineering
computation
mutagenesis
cofactor
File:: Download thesisdraftfinal.pdf
Committee Members:: Costas D Maranas, Thesis Advisor/Co-Advisor
Costas D Maranas, Thesis Advisor/Co-Advisor

Open Access

Author:: Moore, Gregory Lee
Title:: Modeling and Optimization in Directed Evolution Protocols and Protein Engineering
Graduate Program:: Chemical Engineering
Keywords:: directed evolution
protein engineering
optimization
File:: Download thesis.pdf
Committee Members:: Costas D Maranas, Committee Chair/Co-Chair
Ali Borhan, Committee Member
Patrick Cirino, Committee Member
Stephen James Benkovic, Committee Member
Andrew Zydney, Committee Member

Open Access

Author:: Fazelinia, Hossein
Title:: COMPUTATIONAL DESIGN AND EXPERIMENTAL CHARACTERIZATION OF PROTEINS WITH NOVEL FUNCTIONS
Graduate Program:: Chemical Engineering
Keywords:: OptGraft
Protein engineering
Computational protein design
Enzyme cofactor alteration
IPRO
File:: Download Fazelinia_Dissertation.pdf
Committee Members:: Costas D Maranas, Dissertation Advisor/Co-Advisor
Costas D Maranas, Committee Chair/Co-Chair
Patrick Cirino, Committee Chair/Co-Chair
David D Boehr, Committee Member
Andrew Zydney, Committee Member

Open Access

Author:: Jones, Joseph Francis
Title:: Examining Initial Bacterial Adhesion: Oriented Adhesion and Surface Nanodomains
Graduate Program:: Chemical Engineering
Keywords:: bacterial adhesion
bacterial polarity
laser trap
orientation
adhesion
nanodomain
File:: Download 11-02-05_Thesis.pdf
Committee Members:: Darrell Velegol, Committee Chair/Co-Chair
Seong H Kim, Committee Member
Costas D Maranas, Committee Member
John Michael Regan, Committee Member
Andrew Zydney, Committee Member

Open Access

Author:: Chin, Jonathan W
Title:: ENGINEERING AND ANALYSIS OF COFACTOR PARTITIONING FOR NADPH-DEPENDENT XYLITOL PRODUCTION IN ESCHERICHIA COLI
Graduate Program:: Chemical Engineering
Keywords:: xylitol
cofactor regneration
E. coli
metabolic engineering
biotransformation
File:: Download PS_Thesis_JWC_051810_-_Final.pdf
Committee Members:: Dr Patrick Cirino, Dissertation Advisor/Co-Advisor
Patrick Cirino, Committee Chair/Co-Chair
Costas D Maranas, Committee Member
Wayne Roger Curtis, Committee Member
Ali Demirci, Committee Member

Open Access

Author:: Saraf, Manish Chandra
Title:: DEVELOPMENT OF COMPUTATIONAL TOOLS FOR THE DESIGN AND OPTIMIZATION OF COMBINATORIAL PROTEIN LIBRARIES
Graduate Program:: Chemical Engineering
Keywords:: protein engineering
directed evolution
bioinformatics
protein library design
optimization
File:: Download Thesis.pdf
Committee Members:: Michael Pishko, Committee Member
Patrick Cirino, Committee Member
Stephen James Benkovic, Committee Member
Andrew Zydney, Committee Member
Costas D Maranas, Committee Chair/Co-Chair

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