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Author:

Reiter, Chad

Title:

Constitutive insulin receptor signaling in retina and changes induced by diabetes

Graduate Program:

Physiology

Keywords:

insulin receptor
diabetic retinopathy
retina
insulin
signal transduction

File:

Download pdf_of_thesis2_C_REITER.pdf

Committee Members:

Thomas Wright Gardner, Committee Chair/Co-Chair
David A Antonetti, Committee Member
Scot R Kimball, Committee Member
Charles H Lang, Committee Member
Kathryn F Lanoue, Committee Member
Ian Alexander Simpson, Committee Member

Author:

Rizkalla, Hany Waheeb

Title:

The Role of the Wingless Signaling Pathway in Cell Fate Specification

Graduate Program:

Biology

Keywords:

somatic mesoderm
signal transduction
Wnt
Wingless signaling
Drosophila melanogaster
myogenesis
cell specification
founder cell
Zeste white 3
GSK-3

File:

Download HWR_PhD_Thesis.pdf

Committee Members:

Esther Siegfried, Committee Chair/Co-Chair
David Scott Gilmour, Committee Member
Richard W Ordway, Committee Member
Stephen Wade Schaeffer, Committee Member

Author:

Yang, Polung

Title:

REQUIREMENT AND APPROPRIATION OF ACTIVATING SIGNALS BY HIV-1 IN INFECTED CD4+ T CELLS

Graduate Program:

Integrative Biosciences

Keywords:

Human Immunodeficiency Virus
CD4+ T cells
signal transduction
CD28
Nef
Cbl
PI3K
tyrosine phosphorylation
transcription

File:

Download Polung_Yang_Dissertation_December_2005--eTD.pdf

Committee Members:

Andrew Thomas Henderson, Committee Chair/Co-Chair
Avery August, Committee Member
Richard John Frisque, Committee Member
Biao He, Committee Member
Brian Wigdahl, Committee Member

Author:

Weinberg, Rebecca Bronwyn

Title:

INFLAMMATORY CYTOKINE RESPONSES TO MALARIA PARASITE GLYCOSYLPHOSPHATIDYLINOSITOLS

Graduate Program:

Molecular Medicine

Keywords:

malaria
innate immunity
cytokines
signal transduction
macrophages

File:

Download Weinberg_thesis_final_edits.pdf

Committee Members:

Channe D Gowda, Dissertation Advisor/Co-Advisor
Channe D Gowda, Committee Chair/Co-Chair
Jong Kak Yun, Committee Member
Mark Kester, Committee Member
Pamela Hankey Giblin, Committee Member
Todd Schell, Committee Member
Cara Lynne Schengrund, Committee Member

Author:

Romanelli, Robert John

Title:

IGF TYPE I RECEPTOR LOCALIZATION AND TRAFFICKING IN OLIGODENDROCYTE PROGENITOR CELLS: REGULATION OF THE PI-3 KINASE/AKT PATHWAY

Graduate Program:

Cell and Molecular Biology

Keywords:

oligodendrocytes
Akt
signal transduction
IGF-I
lipid rafts
caveolin
receptor trafficking

File:

Download THESIS_rjromanelli.pdf

Committee Members:

Teresa Wood, Committee Chair/Co-Chair
Sarah Bronson, Committee Chair/Co-Chair
Steve Levison, Committee Member
Mark Kester, Committee Member
Shao Cong Sun, Committee Chair/Co-Chair

Author:

Clardy, Stacey Lynn

Title:

BRAIN IRON DEFICIENCY IN HUMANS AND ANIMAL MODELS

Graduate Program:

Cell and Molecular Biology

Keywords:

H ferritin
hepcidin
iron deficiency
brain iron
developmental brain iron deficiency
brain microarray
myelin
solute carrier family
signal transduction
transferrin
L ferritin
cerebrospinal fluid
CSF
immunoblot

File:

Download edt.pdf

Committee Members:

James Robert Connor, Committee Chair/Co-Chair
Ian Alexander Simpson, Committee Member
John Elliot Beard, Committee Member
David A Antonetti, Committee Member
Gary Alan Clawson, Committee Member

Author:

Huang, Weishan

Title:

IDENTIFICATION AND CHARACTERIZATION OF INTERACTIONS BETWEEN ITK AND Gα13

Graduate Program:

Cell and Molecular Biology

Keywords:

protein-protein interaction
Gα13
signal transduction
T cell receptor
Itk
G protein coupled receptor

File:

Download MSTh_Weishan_CDB.pdf

Committee Members:

Avery August, Thesis Advisor/Co-Advisor
Avery August, Thesis Advisor/Co-Advisor

Author:

Yu, Tian

Title:

Integrative analyses of hippo pathway Mutations in human cancer genome

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

mutation
cancer genome
Hippo Pathway
signal transduction
tumor
mutation correlation

File:

Download Tian_Yus_dissertation_Dec_final.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Francisco Javier Diaz, Committee Member
Graham Hugh Thomas, Committee Member
Robert Paulson, Special Member

Author:

Gresock, Michael George

Title:

Conformational Dynamics of the Escherichia coli TonB Protein and Implications for Energy Transduction

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

TonB
FepA
signal transduction
iron transport

File:

Download Michael_G._Gresock_Revised_Final.pdf

Committee Members:

Kathleen Postle, Dissertation Advisor/Co-Advisor
Kathleen Postle, Committee Chair/Co-Chair
Donald Ashley Bryant, Committee Member
B Tracy Nixon, Committee Member
Lorraine C Santy, Committee Member
Timothy W Mcnellis, Committee Member

Author:

Sun, Zhongyao

Title:

Analysis and Logical Modeling of Biological Signaling Transduction Networks

Graduate Program:

Physics

Keywords:

network science
biological networks
discrete dynamics
Boolean network
system biology
network modeling
signal transduction

File:

Download Dissertation_Zhongyao_Sun.pdf

Committee Members:

Reka Z Albert, Dissertation Advisor/Co-Advisor
Reka Z Albert, Committee Chair/Co-Chair
Dezhe Jin, Committee Member
Jorge Osvaldo Sofo, Committee Member
John Fricks, Committee Member

Author:

Gan, Xiao

Title:

Understanding Signal Transduction in Biological Systems with Network-Based Dynamic Modeling

Graduate Program:

Physics

Keywords:

Biological networks
Dynamical modeling
attractors
network reduction
Stable motifs
signal transduction

File:

Download Dissertation-XiaoGan.pdf

Committee Members:

Réka Albert, Dissertation Advisor/Co-Advisor
Réka Albert, Committee Chair/Co-Chair
Carina Curto, Committee Member
Dezhe Jin, Committee Member
Costas D. Maranas, Outside Member

Author:

Baraniak, James

Title:

REVEALING THE ORAI-STIM BINDING INTERFACE THROUGH THE USE OF NOVEL PEPTIDES

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

calcium
store-operated calcium entry
soce
calcium homeostasis
STIM
Orai
Calcium channels
M4x peptide
peptide modulation
Orai binding interface
SOAR
stormorken
signal transduction
NFAT
pan-specific inhibition
stim-orai interacting interface

File:

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Committee Members:

Salvatore Stella, Outside Unit Member
Thomas Spratt, Outside Field Member
Christopher Yengo, Major Field Member
Donald Gill, Chair & Dissertation Advisor
Ralph Keil, Program Head/Chair

Author:

Potter, Jacob

Title:

Studying the Structure and Interactions of the Globin-Coupled Sensor in P. carotovorum

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology (PHD)

Keywords:

Biochemistry
Microbiology
Molecular Biology
SAXS
Pectobacterium
PccGCS
Diguanylate cyclase
c-di-GMP
cryo-EM
globin
globin coupled sensor
oxygen sensing
structural biology
enzyme
oligomer
domain
signal transduction
bacteria
virulence
cross linking
spectroscopy

File:

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Committee Members:

Lorraine Santy, Major Field Member
Scott Showalter, Outside Unit & Field Member
Timothy Miyashiro, Major Field Member
Timothy Meredith, Major Field Member
Wendy Hanna-Rose, Program Head/Chair
Emily Weinert, Chair & Dissertation Advisor