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Author:

Zahr, Alisar

Title:

SOLID CORE-SHELL DRUG NANOPARTICLES FOR THERAPEUTIC DELIVERY

Graduate Program:

Chemical Engineering

Keywords:

nanoparticles
drug delivery
cancer

File:

Download Alisar_Zahr_Thesis_PhD.pdf

Committee Members:

Michael Pishko, Committee Chair/Co-Chair
Christine Dolan Keating, Committee Member
Themis Matsoukas, Committee Member
Andrew Zydney, Committee Member

Author:

DiNatale, Brett C

Title:

The role of the aryl hydrocarbon receptor in tumor cell phenotype

Graduate Program:

Molecular Medicine

Keywords:

ahr
aryl hydrocarbon receptor
cancer

File:

Download Final_11-02-10.PDF

Committee Members:

Gary H Perdew, Dissertation Advisor/Co-Advisor
Gary H Perdew, Committee Chair/Co-Chair
Jeffrey Maurice Peters, Committee Member
Craig Richard Baumrucker, Committee Member
Andrea Marie Mastro, Committee Member
Kumble Sandeep Prabhu, Committee Member

Author:

Thomas, Georgia K

Title:

A MOLECULAR AND SYSTEMS BIOLOGY ANALYSIS OF PLEIOTROPIC VERTEBRATE PHENOTYPES

Graduate Program:

Cell and Molecular Biology

Keywords:

cancer
gene identification
mutagenesis screens
pleiotropy
zebrafish

File:

Download Thesis_FINAL.pdf

Committee Members:

Keith C Cheng, Dissertation Advisor/Co-Advisor
Edward Joseph Gunther, Committee Member
Victor Alan Canfield, Committee Member
Kent Eugene Vrana, Committee Member
Keith C Cheng, Committee Chair/Co-Chair
Sarah Bronson, Committee Member

Author:

Peng, Hsin-Hsin

Title:

INTERCELLULAR AND INTRACELLULAR SIGNALING DURING LEUKOCYTE-MEDIATED MELANOMA CELL TRANSENDOTHELIAL MIGRATION

Graduate Program:

Bioengineering

Keywords:

cancer
signaling
adherens junction
chemokine
extravasation
cytokine

File:

Download thesis_HHP.pdf

Committee Members:

Cheng Dong, Committee Chair/Co-Chair
Andrew Thomas Henderson, Committee Member
Peter J Butler, Committee Member
Avery August, Committee Member

Author:

Slattery, Margaret June

Title:

Neutrophil-mediated Melanoma Adhesion and Migration in Shear Flow

Graduate Program:

Bioengineering

Keywords:

polymorphonuclear leukocytes
cancer
beta2-integrin
ICAM-1
interleukin-8

File:

Download SlatteryMJ_Thesis.pdf

Committee Members:

Cheng Dong, Committee Chair/Co-Chair
William O Hancock, Committee Member
Peter J Butler, Committee Member
Andrew Thomas Henderson, Committee Member

Author:

Nichenametla, Sailendra Nath

Title:

FUNCTIONAL SIGNIFICANCE OF THE GAG TRINUCLEOTIDE-REPEAT POLYMORPHISM IN THE CATALYTIC SUBUNIT OF THE GLUTATHIONE BIOSYNTHETIC ENZYME, g-GLUTAMYLCYSTEINE LIGASE

Graduate Program:

Integrative Biosciences

Keywords:

cancer
trinucleotide repeat polymorphisms
Oxidative stress
glutathione

File:

Download Nichenametla_Sailendra.pdf

Committee Members:

John Peter Richie Jr., Dissertation Advisor/Co-Advisor
John Peter Richie Jr., Committee Chair/Co-Chair
Philip Lazarus, Committee Member
Joshua Ethan Muscat, Committee Member
Scot R Kimball, Committee Member
Curtis John Omiecinski, Committee Member

Author:

Campbell, Colin Edward

Title:

complex dynamics of biological systems

Graduate Program:

Physics

Keywords:

complex systems
network theory
systems biology
cancer
ecosystem stability
immune system

File:

Download Dissertation_-_Colin_Campbell.pdf

Committee Members:

Reka Z Albert, Dissertation Advisor/Co-Advisor
Dezhe Jin, Committee Member
Alexay Kozhevnikov, Committee Member
Istvan Albert, Committee Member

Author:

Khanna, Payal

Title:

Role of CD82 tetraspanins in regulation of extracellular signals within the tumor microenvironment during transendothelial migration

Graduate Program:

Bioengineering

Keywords:

tetraspanins
cytokines
melanoma
cadherins
cancer
endothelial

File:

Download Thesis_draft_July_3rd.pdf

Committee Members:

Cheng Dong, Dissertation Advisor/Co-Advisor
Peter J Butler, Committee Member
Margaret June Slattery, Committee Member
Costas D Maranas, Special Member
Esther Winter Gomez, Special Member

Author:

Xu, Tongtong

Title:

Anti-Cancer Effects of Phenolic-rich Extracts of Button Mushrooms (Agaricus bisporus)

Graduate Program:

Food Science

Keywords:

Agaricus bisporus
mushrooms
cancer
phenolic compounds
apoptosis
microarray
SCID mice
xenograft tumor

File:

Download Final_dissertation_Tongtong_Xu_4-3-2013.pdf

Committee Members:

Joshua D Lambert, Dissertation Advisor/Co-Advisor
Robert Bruce Beelman, Committee Member
Ryan John Elias, Committee Member
John Patrick Vanden Heuvel, Committee Member

Author:

Huang, Changjin

Title:

A Mechanistic Study on Cellular Uptake of Nanoparticles for Enhanced Drug Delivery

Graduate Program:

Engineering Science and Mechanics

Keywords:

Nanoparticle
cellular uptake
substrate stiffness
topography
thermodynamics
molecular dynamics
drug delivery
cancer

File:

Download CJH_Dissertation.pdf

Committee Members:

Sulin Zhang, Dissertation Advisor/Co-Advisor
Sulin Zhang, Committee Chair/Co-Chair
Bernhard R Tittmann, Committee Member
Melik C Demirel, Committee Member
Jian Xu, Committee Member
Peter J Butler, Committee Member
Cheng Dong, Committee Member

Author:

Louis, Christopher John

Title:

Essays on the Organization and Delivery of Cancer Care

Graduate Program:

Health Policy and Administration

Keywords:

organization
cancer
breast cancer
patient navigation
health system
organizational attention
organization design

File:

Download Essays_on_the_Organization_and_Delivery_of_Cancer_Care.pdf

Committee Members:

Jonathan Rogers Clark, Committee Chair/Co-Chair
Susan Diane Brannon, Committee Member
Marianne Messersmith Hillemeier, Committee Member
Barbara Louise Gray, Committee Member
Eugene Joseph Lengerich, Committee Member

Author:

Steinway, Steven Nathaniel

Title:

Predictive Network Modeling And Experimentation In Complex Biological Systems: Applications To Cancer And Infectious Disease

Graduate Program:

Molecular Medicine

Keywords:

Network analysis
dynamic modeling
discrete dynamic modeling
cancer
microbiome
tumor invasion & metastasis

File:

Download Steinway-Thesis-Full-5-20-15.pdf

Committee Members:

Reka Z Albert, Dissertation Advisor/Co-Advisor
"Thomas P Loughran, Jr", Dissertation Advisor/Co-Advisor
Reka Z Albert, Committee Chair/Co-Chair
David J Feith, Committee Member
James Riley Broach, Committee Member
Diane M Thiboutot, Committee Member

Author:

Chen, Xiangyun

Title:

Novel Self-assemble nanoparticles to inhibit cancer growth -effects on ER stress, autophagy, and multidrug resistance by a small molecule

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

Nanomedicine
Multi-drug resistance
cancer

File:

Download XAC-Thesis-20151209-2.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Lu Bai, Committee Member
Gavin Peter Robertson, Special Member

Author:

Prabhu, Varun Vijay

Title:

Therapeutic targeting of chemotherapy-resistant colorectal cancer stem cells with p73- and TRAIL-based small molecules

Graduate Program:

Molecular Medicine

Keywords:

stem cell
cancer
p73
p53
TRAIL
small molecule
ONC201

File:

Download VPrabhu_PhD_Dissertation_040416_corrected_final.pdf

Committee Members:

Wafik S El Deiry, Dissertation Advisor/Co-Advisor
Charles H Lang, Committee Chair/Co-Chair
Hong Gang Wang, Committee Member
Edward Joseph Gunther, Special Member

Author:

Finch, Emily Rebecca

Title:

The role of endogenous lipid mediators in models of experimental leukemia

Graduate Program:

Immunology and Infectious Diseases

Keywords:

NSAID
omega-3
leukemia stem cell
prostaglandin
cancer
leukemia
BCR-ABL

File:

Download Dissertation_EFINCH.pdf

Committee Members:

K. Sandeep Prabhu, Dissertation Advisor/Co-Advisor
Margherita T. Cantorna, Committee Chair/Co-Chair
Robert F. Paulson, Committee Member
Connie J. Rogers, Committee Member
Penny M. Kris-Etherton, Outside Member

Author:

Teye, Emmanuel Kwame

Title:

THE NOVEL MECHANISTIC ROLE OF PIGN IN LEUKEMIA PROGRESSION

Graduate Program:

Biomedical Sciences

Keywords:

myelodysplastic syndrome
acute myeloid leukemia
PIGN
chromosomal instability
risk-stratification
biomarker
spindle assembly checkpoint
leukemia
mitotic exit
GPI anchor biosynthesis
cancer
cell cycle
mitosis

File:

Download PS-Emmanuel_Kwame_Teye_Thesis.pdf

Committee Members:

Jeffrey J Pu, Dissertation Advisor/Co-Advisor
Jong Kak Yun, Committee Chair/Co-Chair
Hong-Gang Wang, Committee Member
Douglas B Stairs, Committee Member
Gregory Steven Yochum, Outside Member

Author:

Weissenrieder, Jillian

Title:

Dopamine D2 Receptor Antagonists as Potential Therapeutics for Glioblastoma Multiforme

Graduate Program:

Biomedical Sciences

Keywords:

cancer
pharmacology
dopamine D2 receptor
antipsychotic
thioridazine
glioblastoma

File:

Download J_Weissenrieder_Dissertation_FINAL_UPDATE.pdf

Committee Members:

Raymond J. Hohl, Dissertation Advisor/Co-Advisor
Jeffrey D Neighbors, Committee Chair/Co-Chair
Kent Eugene Vrana, Committee Member
David James Degraff, Committee Member
Xuemei Huang, Outside Member

Author:

Tran, Linh

Title:

THREE ESSAYS IN HEALTH ECONOMICS: UNDERSTANDING THE EFFECTS OF HEALTH POLICIES AND INSURANCE COVERAGE ON CANCER OUTCOMES

Graduate Program:

Health Policy and Administration (PHD)

Keywords:

cancer
mammography
breast cancer
renal cell carcinoma
Medicare
insurance
dense breast notification

File:

Download Dissertation-formatted-revised-final.pdf

Committee Members:

Douglas Leslie, Outside Unit & Field Member
David Vanness, Major Field Member
Chris Hollenbeak, Major Field Member
Joel Segel, Chair & Dissertation Advisor
Chris Hollenbeak, Program Head/Chair

Author:

Yusko, Brandon Allen

Title:

The Role of the Aryl Hydrocarbon Receptor in Mediating the Migration and Survival of Head and Neck Squamous Cell Carcinoma

Graduate Program:

Molecular, Cellular, and Integrative Biosciences (PHD)

Keywords:

cancer
toxicology

File:

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Committee Members:

Andrew Patterson, Major Field Member
Adam Glick, Major Field Member
Gary Perdew, Chair & Dissertation Advisor
Joshua Lambert, Outside Unit & Field Member
Melissa Rolls, Program Head/Chair

Author:

Leighow, Scott

Title:

Forecasting and Forward Engineering Anticancer Drug Resistance

Graduate Program:

Bioengineering (PHD)

Keywords:

cancer
drug resistance
systems biology
synthetic biology
stochastic modeling
gene therapy

File:

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Committee Members:

David Kennedy, Outside Unit & Field Member
Xiaojun Lian, Major Field Member
Justin Pritchard, Chair & Dissertation Advisor
Daniel Hayes, Program Head/Chair
William Hancock, Major Field Member

Author:

Torab, Peter

Title:

Collective Invasion In Heterogeneous Bladder Cancer Tumors: A Biomanufacturing Approach

Graduate Program:

Mechanical Engineering

Keywords:

bladder
cancer
heterogeneity
invasion
heterogeneous
biomanufacturing
biosensor
biomanufactured
biomanufacture
3D
extracellular matrix
leader cells
collective invasion
invasion assay
in vitro

File:

Download Peter_Torab_Dissertation.pdf

Committee Members:

Pak Kin Wong, Dissertation Advisor/Co-Advisor
Pak Kin Wong, Committee Chair/Co-Chair
Jing Du, Committee Member
Tak Sing Wong, Committee Member
William O Hancock, Outside Member
Daniel Connell Haworth, Program Head/Chair

Author:

Solares Bucaro, Maria

Title:

The Genome's Guardian Angel: A Structural Exploration of p53 in Cancer

Graduate Program:

Molecular, Cellular, and Integrative Biosciences (PHD)

Keywords:

p53
tumor suppressor
structural biology
cryo-em
cancer
molecular modeling

File:

Login to Download

Committee Members:

Melissa Rolls, Program Head/Chair
Mark Hedglin, Outside Unit Member
Susan Hafenstein, Major Field Member
Justin Pritchard, Outside Field Member
Deb Kelly, Chair & Dissertation Advisor

Author:

Frieben, Emily

Title:

Dopamine D1-like receptors: Structure, function, and role in cancer therapeutics

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

dopamine receptors
dopamine
GPCRs
neuropharmacology
functional selectivity
biased agonism
Parkinson's disease
cancer
chemotherapy
drug discovery

File:

Download Frieben_Dissertation_Final.pdf

Committee Members:

Richard Mailman, Co-Chair & Dissertation Advisor
Elizabeth Proctor, Outside Unit Member
Kent Vrana, Major Field Member
Daniel Morgan, Special Member
Nikolay Dokholyan, Co-Chair & Dissertation Advisor
Victor Ruiz-Velasco, Outside Field Member
Ralph Keil, Program Head/Chair