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1. Chemical Synthesis of Base-Modified Ribonucleosides as Novel Antiviral Agents

open_access
Open Access
Author:
Harki, Daniel Allen
Title:
Chemical Synthesis of Base-Modified Ribonucleosides as Novel Antiviral Agents
Graduate Program:
Chemistry
Keywords:
universal base
coxsackievirus
poliovirus
lethal mutagenesis
RNA virus
RNA-dependent RNA polymerase
nucleotides
nucleosides
ribonucleosides
antiviral agents
nucleoside synthesis
File:
Download Harki_PhD_Thesis.pdf
Committee Members:
Blake Peterson, Committee Chair/Co-Chair
Craig Eugene Cameron, Committee Member
Ken S Feldman, Committee Member
Joseph M Bollinger Jr., Committee Member

2. INSIGHT INTO POLIOVIRUS GENOME REPLICATION AND ENCAPSIDATION REVEALED FROM MOLECULAR CHARACTERIZATION OF 3B-3C CLEAVAGE SITE MUTANTS

open_access
Open Access
Author:
Oh, Hyung Suk
Title:
INSIGHT INTO POLIOVIRUS GENOME REPLICATION AND ENCAPSIDATION REVEALED FROM MOLECULAR CHARACTERIZATION OF 3B-3C CLEAVAGE SITE MUTANTS
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
cleavage site mutant
polyprotein processing
replication
poliovirus
complementation
File:
Download Oh_Dissertation_111809.pdf
Committee Members:
Craig Eugene Cameron, Dissertation Advisor/Co-Advisor
Craig Eugene Cameron, Committee Chair/Co-Chair
Kenneth Charles Keiler, Committee Member
B Tracy Nixon, Committee Member
Joseph C. Reese, Committee Member
Philip C. Bevilacqua, Committee Member

3. DESIGN, SYNTHESIS, ANTIVIRAL EVALUATION AND METABOLISM OF NUCLEOSIDE ANALOGS

open_access
Open Access
Author:
Edathil, Jocelyn P
Title:
DESIGN, SYNTHESIS, ANTIVIRAL EVALUATION AND METABOLISM OF NUCLEOSIDE ANALOGS
Graduate Program:
Chemistry
Keywords:
nucleotides
universal base
poliovirus
lethal mutagenesis
nucleoside synthesis
RNA virus
nucleosides
RNA-dependent RNA polymerase
carbohydrate synthesis
nucleoside phosphorylation
File:
Download EdathilThesisFinal.pdf
Committee Members:
Blake R Peterson, Committee Chair/Co-Chair
Gong Chen, Committee Member
Craig Eugene Cameron, Committee Member
Anthony Edward Pegg, Committee Member

4. POLIOVIRUS RNA-DEPENDENT RNA POLYMERASE (IN)FIDELITY: MECHANISMS, CONSEQUENCES AND APPLICATIONS

open_access
Open Access
Author:
Korneeva, Victoria
Title:
POLIOVIRUS RNA-DEPENDENT RNA POLYMERASE (IN)FIDELITY: MECHANISMS, CONSEQUENCES AND APPLICATIONS
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
RNA-dependent RNA polymerase
fidelity
nucleotide selection
poliovirus
File:
Download KorneevaVictoriaPhDThesis.pdf
Committee Members:
Craig Eugene Cameron, Committee Chair/Co-Chair
Squire J Booker, Committee Member
Michael Teng, Committee Member
Ming Tien, Committee Member
Blake R Peterson, Committee Member

5. Viral polymerase mechanism-based strategies for viral attenuation and vaccine development

open_access
Open Access
Author:
Lee, Cheri Annette
Title:
Viral polymerase mechanism-based strategies for viral attenuation and vaccine development
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
RNA dependent RNA polymerase
polymerase fidelity
poliovirus
RNA virus
picornavirus
vaccine
File:
Download Dissertation_LEE_040115.pdf
Committee Members:
Craig Eugene Cameron, Dissertation Advisor/Co-Advisor
Richard John Frisque, Committee Member
Anthony Paul Schmitt, Committee Member
Andrea Marie Mastro, Committee Member
Avery August, Special Member

6. Targeting Viral Proteins To Sites Of Genome Replication: Discovery And Characterization Of Viral Phosphoinositide-Binding Domains

open_access
Open Access
Author:
Shengjuler, Djoshkun
Title:
Targeting Viral Proteins To Sites Of Genome Replication: Discovery And Characterization Of Viral Phosphoinositide-Binding Domains
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
poliovirus
phosphoinositides
PIP-on-a-chip
PI4P
RNA virus
replication organelle
File:
Download Shengjuler_Dissertation_2017_final.pdf
Committee Members:
Craig E. Cameron, Dissertation Advisor/Co-Advisor
Craig E. Cameron, Committee Chair/Co-Chair
Melissa M. Rolls, Committee Member
Moriah L. Szpara, Committee Member
Esther Winter Gomez, Outside Member
Paul S Cremer, Committee Member
B Tracy Nixon, Committee Member