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Author:

Warner, Brittany A

Title:

A Structural Study of Bacterial Rna Polymerase Conformational Changes During Transcription Elongation

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

RNA polymerase
translocation
Thermus thermophilus
X-ray crystallography

File:

Download Warner-thesis.pdf

Committee Members:

Katsuhiko Murakami, Thesis Advisor/Co-Advisor
David Scott Gilmour, Thesis Advisor/Co-Advisor
Tae Hee Lee, Thesis Advisor/Co-Advisor
Paul Lee Babitzke, Thesis Advisor/Co-Advisor

Author:

Basu, Ritwika

Title:

Mechanistic investigations of nucleotidyl-transfer reaction and de novo initiation in Rna polymerases by X-ray crystallography

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

soak-trigger freeze X-ray crystallography
nucleotidyl-transfer reaction
RNA polymerase
N4 bacteriophage
Thermus thermophilus

File:

Download Final_Dissertation.pdf

Committee Members:

Katsuhiko Murakami, Dissertation Advisor/Co-Advisor
Katsuhiko Murakami, Committee Chair/Co-Chair
Craig Eugene Cameron, Committee Member
Paul Lee Babitzke, Committee Member
Andrey S Krasilnikov, Committee Member
Scott A Showalter, Committee Member