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Author:

Basu, Ritwika

Title:

Mechanistic investigations of nucleotidyl-transfer reaction and de novo initiation in Rna polymerases by X-ray crystallography

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

soak-trigger freeze X-ray crystallography
nucleotidyl-transfer reaction
RNA polymerase
N4 bacteriophage
Thermus thermophilus

File:

Download Final_Dissertation.pdf

Committee Members:

Katsuhiko Murakami, Dissertation Advisor/Co-Advisor
Katsuhiko Murakami, Committee Chair/Co-Chair
Craig Eugene Cameron, Committee Member
Paul Lee Babitzke, Committee Member
Andrey S Krasilnikov, Committee Member
Scott A Showalter, Committee Member

Author:

Wang, Shu

Title:

Peptidylarginine deiminase inhibitors regulate autophagy of human cancer cells and inflammation response of immune cells

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

PAD inhibitor; cancer epigenetics; ChIP-exo; citrullination; ER

File:

Download Shu_Wang_Dissertation_final.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Yanming Wang, Committee Chair/Co-Chair
Andrea Marie Mastro, Committee Member
David Scott Gilmour, Committee Member
Gong Chen, Committee Member
Robert Paulson, Committee Member

Author:

Gresock, Michael George

Title:

Conformational Dynamics of the Escherichia coli TonB Protein and Implications for Energy Transduction

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

TonB
FepA
signal transduction
iron transport

File:

Download Michael_G._Gresock_Revised_Final.pdf

Committee Members:

Kathleen Postle, Dissertation Advisor/Co-Advisor
Kathleen Postle, Committee Chair/Co-Chair
Donald Ashley Bryant, Committee Member
B Tracy Nixon, Committee Member
Lorraine C Santy, Committee Member
Timothy W Mcnellis, Committee Member

Author:

El-mowafi, Shaima

Title:

Development and Validation of Screens For Drugs targeting Gram-negative Bacteria

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Gram-negative pathogens
virulence
σE-sRNA-Hfq pathway
cyclic peptides

File:

Download thesis_Shaima_El-mowafi.pdf

Committee Members:

Kenneth Charles Keiler, Dissertation Advisor/Co-Advisor
Sarah Ellen Ades, Committee Member
Katsuhiko Murakami, Committee Member
Squire J Booker, Committee Member
Michael Axtell, Committee Member

Author:

Muse, Sarah Jane

Title:

Virulence and Infection: Interactions between Bordetella bronchiseptica and The Immune System

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Bordetella bronchiseptica
secretion system
host-pathogen interactions
inflammasome

File:

Download SJM_Dissertation_in_template__v.15_.pdf

Committee Members:

Eric Thomas Harvill, Dissertation Advisor/Co-Advisor
Andrea Marie Mastro, Committee Member
Robert Paulson, Committee Member
Kumble Sandeep Prabhu, Special Member

Author:

Deng, Yaoting

Title:

Regulation of Hippo Signaling for Growth Control

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Hippo pathway
Hippo
transphosphorylation
dimerization
Merlin
Expanded
Kibra
FFA
β-cells
Yap
F-actin
apoptosis

File:

Download Dissertation_Yaoting_Deng.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Pamela Hankey Giblin, Committee Member
Richard W Ordway, Committee Member
Wendy Hanna Rose, Committee Member
Yanming Wang, Committee Member

Author:

Dogan, Nergiz

Title:

Elucidating Biological Function of Genomic DNA with Robust Signals of Biochemical Activity: Integrative Genome-wide Studies of Enhancers

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Functional genomics
Gene regulation
TAL1
GATA1
Histone modifications
Enhancer assay

File:

Download Dogan_PhDThesis_final.pdf

Committee Members:

Ross Cameron Hardison, Dissertation Advisor/Co-Advisor
Ross Cameron Hardison, Committee Chair/Co-Chair
David Scott Gilmour, Committee Member
Robert Paulson, Committee Member
Philip L Reno, Committee Member
Anton Nekrutenko, Committee Member

Author:

Zhao, Na

Title:

Investigation of the molecular genetics of Drosophila synapse assembly

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

synapse development
GluRIIA localization
subsynaptic reticulum
Akt
heparan sulfate proteolycan
autophagy
Acinus
spectrin

File:

Download Dissertation_Thesis-_Na_Zhao_final_submission.pdf

Committee Members:

Scott Brian Selleck, Dissertation Advisor/Co-Advisor
Scott Brian Selleck, Committee Chair/Co-Chair
Bernhard Luscher, Committee Member
Richard W Ordway, Committee Member
Zhi Chun Lai, Committee Member

Author:

Wang, Wenqing

Title:

Tissue specific effects of NAD+ biosynthesis on muscle function, fat metabolism and gonad development in Caenorhabditis elegans

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

NAD+
vitamin B3
nicotinamidase
nicotinamide riboside
quinolinic acid
metabolomics
glucose metabolism
lipid metabolism

File:

Download Dissertation_revised_Wenqing_Wang_fall_2014.pdf

Committee Members:

Wendy Hanna Rose, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Lorraine C Santy, Committee Member
Scott Brian Selleck, Committee Member
Ramesh Ramachandran, Committee Member

Author:

Gan, Fei

Title:

Acclimative remodeling of the photosynthetic apparatus in response to light and iron limitation in Leptolyngbya sp. JSC-1

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

cyanobacteria
photosynthesis
acclimation
far-red light
iron stress

File:

Download Fei_Gan_Thesis_11-25-14.pdf

Committee Members:

Donald Bryant, Dissertation Advisor/Co-Advisor
Ying Gu, Committee Member
Jennifer Macalady, Committee Member
John H Golbeck, Committee Member
B Tracy Nixon, Committee Member