1. Mechanistic investigations of nucleotidyl-transfer reaction and de novo initiation in Rna polymerases by X-ray crystallography Open Access Author: Basu, Ritwika Title: Mechanistic investigations of nucleotidyl-transfer reaction and de novo initiation in Rna polymerases by X-ray crystallography Graduate Program: Biochemistry, Microbiology, and Molecular Biology Keywords: soak-trigger freeze X-ray crystallographynucleotidyl-transfer reactionRNA polymeraseN4 bacteriophageThermus thermophilus File: Download Final_Dissertation.pdf Committee Members: Katsuhiko Murakami, Dissertation Advisor/Co-AdvisorKatsuhiko Murakami, Committee Chair/Co-ChairCraig Eugene Cameron, Committee MemberPaul Lee Babitzke, Committee MemberAndrey S Krasilnikov, Committee MemberScott A Showalter, Committee Member