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Start Over Degree PHD Committee Member Philip C. Bevilacqua Committee Member Squire J Booker

1. Investigation of the Structure, Function, and Regulation of Quinolinate Synthase: the Iron-Sulfur Cluster Enzyme Involved in Prokaryotic NAD+ Biosynthesis

open_access
Open Access
Author:
Saunders, Allison Hoover
Title:
Investigation of the Structure, Function, and Regulation of Quinolinate Synthase: the Iron-Sulfur Cluster Enzyme Involved in Prokaryotic NAD+ Biosynthesis
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
NadA
iron-sulfur cluster
NAD
enzyme
File:
Download Saunders_Thesis.pdf
Committee Members:
Squire J Booker, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Chair/Co-Chair
Joseph M Bollinger Jr., Committee Member
Carsten Krebs, Committee Member
Ming Tien, Committee Member
Philip C. Bevilacqua, Committee Member

2. Protein Control of Dioxygen Activation, Substrate-Hydrogen Abstraction, and Ligand-Radical-Transfer Outcome in the Aliphatic Halogenase, SyrB2

open_access
Open Access
Author:
Matthews, Megan Leigh
Title:
Protein Control of Dioxygen Activation, Substrate-Hydrogen Abstraction, and Ligand-Radical-Transfer Outcome in the Aliphatic Halogenase, SyrB2
Graduate Program:
Chemistry
Keywords:
oxygen activation
carbon-hydrogen bond activation
alpha-ketoglutarate
halogenation
File:
Download thesis_final.pdf
Committee Members:
J Martin Bollinger Jr And Carsten Krebs, Dissertation Advisor/Co-Advisor
Carsten Krebs, Committee Chair/Co-Chair
J Martin Bollinger Jr, Committee Chair/Co-Chair
Squire J Booker, Committee Member
Philip C. Bevilacqua, Committee Member
Christopher Albert Mullin, Committee Member

3. Folding Cooperativity and Its Influence on pKa Shifting in Nucleic Acids

open_access
Open Access
Author:
Siegfried, Nathan A.
Title:
Folding Cooperativity and Its Influence on pKa Shifting in Nucleic Acids
Graduate Program:
Chemistry
Keywords:
pKa shift
RNA
DNA
nucleic acids
cooperativity
acid base catalysis
File:
Download Siegfried_Thesis.pdf
Committee Members:
Philip C. Bevilacqua, Dissertation Advisor/Co-Advisor
Philip C. Bevilacqua, Committee Chair/Co-Chair
Squire J Booker, Committee Member
Scott A Showalter, Committee Member
Katsuhiko Murakami, Committee Member

4. Showcasing two C-h bond-cleaving manifolds through mechanistic studies of isopenicillin N synthase

open_access
Open Access
Author:
Tamanaha, Esta Yuuka
Title:
Showcasing two C-h bond-cleaving manifolds through mechanistic studies of isopenicillin N synthase
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
IPNS
isopenicillin N synthase
ACV
ferryl
ferric-superoxide
File:
Download Esta_Dissertation-GradSchoolFinal5-CorrectedSubmission.pdf
Committee Members:
Joseph M Bollinger Jr., Dissertation Advisor/Co-Advisor
Carsten Krebs, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Member
Ming Tien, Committee Member
Philip C. Bevilacqua, Committee Member

5. Development and utilization of spectroscopic and chemical methodologies for investigating pKa shifting in nucleic acids

open_access
Open Access
Author:
Wilcox, Jennifer Lynn
Title:
Development and utilization of spectroscopic and chemical methodologies for investigating pKa shifting in nucleic acids
Graduate Program:
Chemistry
Keywords:
RNA
nucleic acids
2-aminopurine fluorescence
pKa shifting
File:
Download Wilcox_Thesis.pdf
Committee Members:
Philip C. Bevilacqua, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Member
Scott A Showalter, Committee Member
Andrey S Krasilnikov, Committee Member

6. toward understanding RNA structure, folding, and function in cells

open_access
Open Access
Author:
Strulson, Christopher A
Title:
toward understanding RNA structure, folding, and function in cells
Graduate Program:
Chemistry
Keywords:
RNA
ribozyme
molecular crowding
macromolecular crowding
catalysis
compartmentalization
folding cooperativity
File:
Download Christoper_Strulson_Thesis_Toward_Understanding_RNA__Structure_Folding_and_Function_in_Cells.pdf
Committee Members:
Philip C. Bevilacqua, Dissertation Advisor/Co-Advisor
Christine Dolan Keating, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Member
Tae Hee Lee, Committee Member
Kenneth Charles Keiler, Committee Member

7. Investigations of the Mechanistic Pathways of the Hepatitis Delta Virus Ribozyme

open_access
Open Access
Author:
Thaplyal, Pallavi
Title:
Investigations of the Mechanistic Pathways of the Hepatitis Delta Virus Ribozyme
Graduate Program:
Chemistry
Keywords:
Ribozyme
Kinetics
HDV
pKa
QM/MM
Thio Effects
Metal Ion Rescue
File:
Download Thesis_PTFinal.pdf
Committee Members:
Philip C. Bevilacqua, Dissertation Advisor/Co-Advisor
Philip C. Bevilacqua, Committee Chair/Co-Chair
Squire J Booker, Committee Member
Lasse Jensen, Committee Member
Katsuhiko Murakami, Special Member

8. Structural Basis for Alternative Reaction Outcome by the Iron- and 2-oxoglutarate-dependent Oxygenases

open_access
Open Access
Author:
Mitchell, Andrew James
Title:
Structural Basis for Alternative Reaction Outcome by the Iron- and 2-oxoglutarate-dependent Oxygenases
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
metalloenzymes
x-ray crystallography
halogenation
Fe/2OG oxygenases
File:
Download mitchell_disserataion_2017.pdf
Committee Members:
Amie K. Boal, Dissertation Advisor/Co-Advisor
Wendy Hanna-Rose, Committee Chair/Co-Chair
Carsten Krebs, Committee Member
Joseph M Bollinger Jr., Committee Member
Philip C. Bevilacqua, Outside Member
Squire J Booker, Committee Member
Benjamin D Allen, Special Member