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Open Access

Author:: Pisupati, Aditya
Title:: Structure-Function Relationships and Biochemical Manipulation of 6-TM Superfamily Ion Channels
Graduate Program:: Neuroscience
Keywords:: ion channels
voltage-gated
structure
function
six-transmembrane
6-TM
Shaker
CNBD
TRPV
File:: Download AP_Thesis_Final.pdf
Committee Members:: Timothy J Jegla, Dissertation Advisor/Co-Advisor
Timothy J Jegla, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Bernhard Luscher, Committee Member
William O Hancock, Outside Member
Santhosh Girirajan, Committee Member

Open Access

Author:: Shipley, Mackenzie Marie
Title:: Examining the Link Between Viral Genotype and Disease Phenotype Using Clinical Cases of HSV-1 and a Human Neuronal Model
Graduate Program:: Biochemistry, Microbiology, and Molecular Biology
Keywords:: herpes simplex virus
genomics
infection
genital
neonatal
neurobiology
File:: Download ShipleyMM_PSU_Dissertation2018_Final.pdf
Committee Members:: Moriah Louise Szpara, Dissertation Advisor/Co-Advisor
Moriah Louise Szpara, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Richard J. Frisque, Committee Member
John Warren Wills, Outside Member
Lorraine C Santy, Committee Member

Open Access

Author:: Brittingham, Jacob Charles
Title:: CHARACTERIZATION OF PDX1 AND ITS INTERACTIONS WITH SPOP
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: PDX1
SPOP
File:: Download Emerging_role_of_intrinsically_disordered_protein_regions.pdf
Committee Members:: Scott A Showalter, Thesis Advisor/Co-Advisor
Melissa Rolls, Committee Member
Lorraine C Santy, Committee Member

Open Access

Author:: Lu, Feiyue
Title:: MOLECULAR ANALYSES OF THE DROSOPHILA RNA POLYMERASE II CARBOXY-TERMINAL DOMAIN
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: RNA Pol II CTD
consensus heptads
divergent motifs
transcription compartment
Drosophila genetics
File:: Download Lu_thesis_final_final.pdf
Committee Members:: David Scott Gilmour, Dissertation Advisor/Co-Advisor
David Scott Gilmour, Committee Chair/Co-Chair
Benjamin Franklin Pugh, Committee Member
Melissa Rolls, Committee Member
Scott A Showalter, Outside Member
Joseph C. Reese, Committee Member
Claire Madison Thomas, Committee Member

Open Access

Author:: Glatzer, Laura
Title:: LOCALIZATION AND FUNCTIONALITY OF ION CHANNELS PRESENT IN THE DROSOPHILA MELANOGASTER AXON INTIAL SEGMENT
Graduate Program:: Neuroscience
Keywords:: voltage-gated potassium channels
axon initial segment
drosophila melanogaster
two-electrode voltage clamp
voltage-gated calcium channels
giant-ankyrin
File:: Download Glatzer_Laura_MastersThesis_Final_Version.pdf
Committee Members:: Timothy J Jegla, Thesis Advisor/Co-Advisor
Melissa Rolls, Committee Member
Kevin Douglas Alloway, Committee Member

Open Access

Author:: Feng, Mengyang
Title:: ELUCIDATION OF MECHANISMS THAT DETERMINE THE RESPONSIVENESS TO ANTIDEPRESSANT DRUG TREATMENTS
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: Depression
Antidepressant
Neuroinflammation
High fat diet
Obesity
Ketamine
File:: Download MengyangFeng_Dissertation.pdfDownload Mengyang_Feng_Erratum.pdf
Committee Members:: Bernhard Luscher, Dissertation Advisor/Co-Advisor
Bernhard Luscher, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Timothy J Jegla, Committee Member
Pamela Hankey Giblin, Outside Member
Jeffrey Maurice Peters, Committee Member

Open Access

Author:: Jiang, Xueyuan
Title:: Sequence and Expression Evolution of Animal and Plant Genes
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: Sequence evolution; Expression evolution
File:: Download Xueyuan_Jiang_Dissertation.pdf
Committee Members:: Raquel Assis, Dissertation Advisor/Co-Advisor
Stephen Wade Schaeffer, Committee Chair/Co-Chair
Shaun Mahony, Committee Member
Yifei Huang, Committee Member
Qunhua Li, Outside Member
Melissa Rolls, Program Head/Chair
Raquel Assis, Committee Chair/Co-Chair
Stephen Wade Schaeffer, Dissertation Advisor/Co-Advisor

Open Access

Author:: Hu, Kai
Title:: Bioinformatics discovery of chemical diversity in enzyme superfamilies
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: Ribonucleotide Reductase (RNR)
Bioinformatics
Radical chemistry
Class Ie RNR
Deep Mutational Scanning (DMS) strategy
File:: Download Kai_Hu_dissertation_for_submission.pdf
Committee Members:: Benjamin D Allen, Dissertation Advisor/Co-Advisor
Joseph M Bollinger, Jr., Committee Chair/Co-Chair
Amie Kathleen Boal, Outside Member
Ross Cameron Hardison, Committee Member
Melissa Rolls, Program Head/Chair

Open Access

Author:: Venkatachalam Srinivasan, Sreenidhi
Title:: Improved diagnosis and control of Bovine Tuberculosis
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: Bovine Tuberculosis
endemic
diagnosis
vaccine
File:: Download Thesis_04132020.pdf
Committee Members:: Vivek Kapur, Dissertation Advisor/Co-Advisor
Vivek Kapur, Committee Chair/Co-Chair
P Hudson, Committee Member
Suresh Varma Kuchipudi, Committee Member
Erika Korzune Ganda, Outside Member
Melissa Rolls, Program Head/Chair

Open Access

Author:: Wang, Xin
Title:: neuronal conversion of human glioblastoma cells by single neuronal transcription factor
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: neuronal conversion
Neurog2
NeuroD1
Ascl1
glioblastoma
File:: Download Dissertation_Xin.pdf
Committee Members:: Yingwei Mao, Dissertation Advisor/Co-Advisor
Yingwei Mao, Committee Chair/Co-Chair
Timothy J Jegla, Committee Member
Xiaojun Lance Lian, Committee Member
Adam Bleier Glick, Outside Member
Gong Chen, Committee Chair/Co-Chair
Gong Chen, Dissertation Advisor/Co-Advisor
Melissa Rolls, Program Head/Chair

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