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Author:

Bui, Pho

Title:

Nonadditive Effects of Cosolvent Mixtures on Protein Stability in Aqueous Solutions

Graduate Program:

Chemistry (PHD)

Keywords:

nonadditivity
ion specific effects
ion-pairing
cosolvent
protein stability
complex solutions
vibrational spectroscopy

File:

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Committee Members:

Paul Cremer, Chair & Dissertation Advisor
William Noid, Major Field Member
Tae-Hee Lee, Major Field Member
Lauren Zarzar, Major Field Member
Philip Bevilacqua, Program Head/Chair
Seong Kim, Outside Unit & Field Member

Author:

Judd, Kenneth Duane

Title:

Investigating Specific Cation Interactions with Anionic Surfactant Monolayers at the Air/Water Interface Using Nonlinear Spectroscopy and Thermodynamics

Graduate Program:

Chemistry (PHD)

Keywords:

ion pairing
ion specific effects
monolayers
spectroscopy
nonlinear optics
vibrational spectroscopy
thermodynamics
surfactants

File:

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Committee Members:

Paul Cremer, Chair & Dissertation Advisor
Benjamin Lear, Major Field Member
Seong Kim, Outside Unit & Field Member
Mark Maroncelli, Major Field Member
Philip Bevilacqua, Program Head/Chair

Author:

Dey, Madhuri

Title:

Reconstituting the 3D Breast Cancer Microenvironment for Chemo and Immunotherapy

Graduate Program:

Chemistry (PHD)

Keywords:

Breast cancer
3D tumor models
Chemotherapy
Immunotherapy
MAIT-MR1
3D bioprinting
Perfusion
Tumor Angiogenesis
Cancer Invasion

File:

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Committee Members:

Paul Cremer, Major Field Member
James Connor, Outside Unit & Field Member
Christine Keating, Co-Chair & Dissertation Advisor
Lauren Zarzar, Major Field Member
Philip Bevilacqua, Program Head/Chair
Ibrahim Ozbolat, Co-Chair & Dissertation Advisor

Author:

Crowe, Charles

Title:

Aqueous Phase Separation within Water-in-Oil Emulsions as Cellular Models

Graduate Program:

Chemistry (PHD)

Keywords:

liquid-liquid phase separation
phase separation
microfluidics
neutral polymer phase separation
emulsion
water-in-oil
coacervation
bioinspired
artificial cell
microscopy
droplet

File:

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Committee Members:

Philip Bevilacqua, Program Head/Chair
Paul Cremer, Major Field Member
Peter Butler, Outside Unit & Field Member
Scott Showalter, Major Field Member
Christine Keating, Chair & Dissertation Advisor

Author:

Liu, Chang

Title:

A Fluorescence-Based Investigation into the Mechanisms of Biomimetic-Membrane Component Translocation

Graduate Program:

Chemistry (PHD)

Keywords:

chemotaxis
lipid flip-flop
membrane component translocation
microfluidics
lipid bilayer

File:

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Committee Members:

Paul Cremer, Chair & Dissertation Advisor
William Hancock, Outside Unit & Field Member
Tae-Hee Lee, Major Field Member
Lauren Zarzar, Major Field Member
Philip Bevilacqua, Program Head/Chair

Author:

Glaid, Andrew

Title:

Interesting Interface Interactions: The Synthesis of Metal Metalattices and the Binding of Ions to Lipid Membranes

Graduate Program:

Chemistry (PHD)

Keywords:

Metalattice
Supercritical Fluid Deposition
Supported Lipid Bilayer
Ion Binding
Microfluidic Assay

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Committee Members:

Venkatraman Gopalan, Outside Unit & Field Member
Kenneth Knappenberger, Major Field Member
Lauren Zarzar, Major Field Member
Philip Bevilacqua, Program Head/Chair
Paul Cremer, Chair & Dissertation Advisor

Author:

Graff, Erica

Title:

The Study of Protein and Polymer Phase Separation Kinetics and Thermodynamics Using Temperature Gradient Microfluidics

Graduate Program:

Chemistry (PHD)

Keywords:

phase separation
monoclonal antibodies
temperature gradient microfluidics
apparent activation energies

File:

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Committee Members:

Paul Cremer, Chair & Dissertation Advisor
Philip Bevilacqua, Major Field Member
Alexey Silakov, Major Field Member
Darrell Velegol, Outside Unit & Field Member
Philip Bevilacqua, Program Head/Chair

Author:

Reynolds, Christopher

Title:

Copper (II) Interactions with Phosphatidylserine in Membranes: Biophysical Insights, Binding Mechanisms, and Physiological Consequences

Graduate Program:

Chemistry (PHD)

Keywords:

biophysical chemistry
transition metal ions
membranes
copper (II)
oxidative damage
supported lipid bilayer
microfluidic systems
binding
phosphatidylserine
lipids
stepwise
constants
stoichiometry
densities
concentrations
Gouy-Chapman theory
ionic strength
surface charge density
chelation
complexes
buffer molecules
physiological implications
HeLa cells
plasma membrane
necrotic cell death
hydrogen peroxide
harmful effects
mechanistic explanation
future experiments.
hrmful effects
Phospholipid membranes
oxidation
copper
membrane oxidation
membrane binding model
bivalent binding
Debye-Hukel Theory
Electrostatic screening
electric double layer
Necrotic cell death
copper induced cell death
Alzheimer's disease
Neurodegeneration
microfluidic devices
high-throughput microfluidics

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Committee Members:

Paul Cremer, Chair & Dissertation Advisor
William Hancock, Outside Unit & Field Member
Alexey Silakov, Major Field Member
Lauren Zarzar, Major Field Member
Philip Bevilacqua, Program Head/Chair

Author:

Choi, Saehyun

Title:

COMPLEX COACERVATES AS EXPERIMENTAL MODEL SYSTEMS FOR PREBIOTIC COMPARTMENTS AND CELLULAR BIOCONDENSATES

Graduate Program:

Chemistry (PHD)

Keywords:

Coacervates
liquid-liquid phase separation
origin of life
protocell
biocondensates
RNA chemistry
thermodynamics

File:

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Committee Members:

Paul Cremer, Major Field Member
Christine Keating, Chair & Dissertation Advisor
Philip Bevilacqua, Major Field Member
Philip Bevilacqua, Program Head/Chair
Christopher House, Outside Unit & Field Member

Author:

Zaniewski, Taylor

Title:

Chemomechanical Characterization of the Superprocessive Kinesin-3 KIF1A

Graduate Program:

Chemistry (PHD)

Keywords:

kinesin
enzyme kinetics
single molecule
biochemistry
biophysics

File:

Download Zaniewski_Dissertation_2022Aug29.pdf

Committee Members:

Paul Cremer, Major Field Member
William Hancock, Co-Chair & Dissertation Advisor
Melissa Rolls, Outside Unit & Field Member
Tae-Hee Lee, Major Field Member
Christine Keating, Co-Chair of Committee
Philip Bevilacqua, Program Head/Chair