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Open Access

Author:: Vilchez Mercedes, Samuel
Title:: The Role of NRF2 in Collective Cancer Invasion
Graduate Program:: Bioengineering (PHD)
Keywords:: Hybrid E/M
Cancer
Bladder Cancer
Notch signaling
Leader cells
EMT
Collective Migration
NRF2
File:: Download SV_Dissertation_final_noBoxes.pdf
Committee Members:: Peter Butler, Major Field Member
Yong Wang, Major Field Member
Zhi-Chun Lai, Outside Unit & Field Member
Daniel Hayes, Program Head/Chair
Pak Kin Wong, Chair & Dissertation Advisor

Open Access

Author:: Agrawal, Sumit
Title:: Intelligent Ultrasound and Photoacoustic Imaging Systems: Design, Development and Beyond
Graduate Program:: Bioengineering (PHD)
Keywords:: ultrasound imaging
photoacoustic imaging
artificial intelligence
spectral unmixing
artifact removal
low-cost devices
portable medical imaging device
File:: Download PhD_Thesis_Sumit_Agrawal.pdf
Committee Members:: Sri-Rajasekhar Kothapalli, Chair & Dissertation Advisor
William Higgins, Major Field Member
Nanyin Zhang, Major Field Member
Vishal Monga, Outside Unit & Field Member
Daniel Hayes, Program Head/Chair

Open Access

Author:: Abune, Lidya
Title:: Development of a Biomimetic Extracellular Matrix Using Aptamers and Hydrogels
Graduate Program:: Bioengineering (PHD)
Keywords:: Aptamer
Biomimetic extracellular matrix
Hydrogel
Protein release
Cell attachment
File:: Download Dissertation-Lidya-Abune-2022.pdf
Committee Members:: Peter Butler, Major Field Member
Yong Wang, Chair & Dissertation Advisor
Jian Yang, Major Field Member
Daniel Hayes, Program Head/Chair
Ralph Colby, Outside Unit & Field Member

Open Access

Author:: Yoas, Zachary
Title:: Passive Trailing Edge Noise Attenuation With Porosity, Inspired By Owl Plumage
Graduate Program:: Bioengineering (MS)
Keywords:: aeroacoustics
porosity
trailing edge noise
vortex rings
owl wings
File:: Download MS_Thesis_Zachary_Yoas_v2.pdf
Committee Members:: Daniel Hayes, Program Head/Chair
Michael H Krane, Thesis Advisor/Co-Advisor
Adam S Nickels, Committee Member
William O Hancock, Committee Member

Open Access

Author:: Sloand, Janna
Title:: EXPLOITING THE FLUOROUS EFFECT TO CREATE SUPRAMOLECULAR FLUOROPEPTIDE MATERIALS
Graduate Program:: Bioengineering (PHD)
Keywords:: Fluorous Effect
Perfluorocarbons
Peptides
Self-Assembly
Templated Assembly
Protein Delivery
Ultrasound
File:: Download Janna_Sloand_-_PhD_-_Dissertation_v6.pdf
Committee Members:: William Hancock, Major Field Member
Justin Brown, Major Field Member
Scott Medina, Chair & Dissertation Advisor
Daniel Hayes, Major Field Member
Julianna Simon, Outside Unit & Field Member
Daniel Hayes, Program Head/Chair

Open Access

Author:: Hiller, Gretchen
Title:: Investigation into the Effects of Fixation on the Mechanical Properties of Acute Ischemic Stroke Embolus Analogs
Graduate Program:: Biomedical Engineering (MS)
Keywords:: acute ischemic stroke
stroke
clot
thrombosis
embolization
blood analog
mechanical
viscoelastic
elastic modulus
histology
File:: Download Hiller_Thesis.pdf
Committee Members:: Keefe B Manning, Thesis Advisor/Co-Advisor
Francesco Costanzo, Committee Member
Daniel Hayes, Program Head/Chair
Peter Butler, Committee Member

Restricted (Penn State Only)

Author:: Khandare, Sujata
Title:: Mechanical response of tendons to common therapies and the effects of tendon injury progression
Graduate Program:: Bioengineering (PHD)
Keywords:: Dry needling
Focused ultrasound
Tendon
Mechanical properties
Mechanical testing
Rotator cuff
Computational model
Glenohumeral joint
Muscle activation
Force couple
Tear severity
Rotator cuff tear
File:: Login to Download
Committee Members:: Stephen Piazza, Outside Unit & Field Member
Spencer Szczesny, Major Field Member
Meghan Vidt, Chair & Dissertation Advisor
Julianna Simon, Major Field Member
Daniel Hayes, Program Head/Chair

Restricted

Author:: Alden, Nicholas
Title:: Nanoparticle-Enhanced Drug Delivery: Delivering Small Nucleic Acid Therapeutics to Combat Disease at the Gene Expression Level
Graduate Program:: Bioengineering (PHD)
Keywords:: Plasmonic Nanoparticles
Near-Infrared
Diels-Alder
Synthetic miRNA Mimics
Head & Neck Cancer
Lung Cancer
Poly-Beta(Amino Esters)
Nanoparticles
Drug Delivery Systems
File:: No files available due to restrictions.
Committee Members:: Daniel Hayes, Program Head/Chair
Adam Glick, Outside Unit & Field Member
Pak Kin Wong, Major Field Member
Yong Wang, Major Field Member
Scott Medina, Major Field Member
Daniel Hayes, Chair & Dissertation Advisor

Restricted

Author:: Lawanprasert, Atip
Title:: Investigating the bioeffects of perfluoroalkyls towards advanced image-guided protein delivery technologies
Graduate Program:: Bioengineering (PHD)
Keywords:: Drug Delivery
Fluorine
Ultrasound
Protein
File:: No files available due to restrictions.
Committee Members:: Scott Medina, Chair & Dissertation Advisor
Daniel Hayes, Major Field Member
Daniel Hayes, Program Head/Chair
William Hancock, Major Field Member
Joseph Cotruvo, Outside Unit & Field Member

Open Access

Author:: Inam, Haider
Title:: Using deep mutational scanning to quantify resistance to targeted anticancer therapies at scale
Graduate Program:: Biomedical Engineering (PHD)
Keywords:: Deep mutational scanning
Drug resistance
BCRABL
Functional genomics
Duplex Sequencing
Cancer evolution
File:: Download Thesis_Compiled_07.10.23.pdf
Committee Members:: Pak Kin Wong, Major Field Member
Xiaojun Lian, Major Field Member
Edward O'Brien, Outside Unit & Field Member
Justin Pritchard, Chair & Dissertation Advisor
William Hancock, Major Field Member
Michael Lee, Special Member
Daniel Hayes, Program Head/Chair

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