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Author:

Prabhu, Varun Vijay

Title:

Therapeutic targeting of chemotherapy-resistant colorectal cancer stem cells with p73- and TRAIL-based small molecules

Graduate Program:

Molecular Medicine

Keywords:

stem cell
cancer
p73
p53
TRAIL
small molecule
ONC201

File:

Download VPrabhu_PhD_Dissertation_040416_corrected_final.pdf

Committee Members:

Wafik S El Deiry, Dissertation Advisor/Co-Advisor
Charles H Lang, Committee Chair/Co-Chair
Hong Gang Wang, Committee Member
Edward Joseph Gunther, Special Member

Author:

Karelia, Deepkamal Nilkamal

Title:

DISCOVERY OF NOVEL Se-ASPIRIN MOLECULES AS POTENTIAL THERAPEUTICS FOR GASTROINTESTINAL CANCERS

Graduate Program:

Molecular Toxicology

Keywords:

Pancreatic cancer
colorectal cancer
small molecule
NSAIDs
apoptotsis
inflammatory pathways
selenium
aspirin
cell cycle
MTT
EMSA
Panc-1

File:

Download Final.pdf

Committee Members:

Arun Kumar Sharma, Dissertation Advisor/Co-Advisor
Arun Kumar Sharma, Committee Chair/Co-Chair
Shantu G Amin, Committee Member
Jong Kak Yun, Committee Member
Victor J Ruiz-Velasco, Outside Member
Rosalyn Bryson Irby, Committee Member

Author:

sun, jinquan

Title:

A NOVEL SMALL MOLECULE DNA INTERCALATOR PZ1225 IN CANCER CELL APOPTOSIS AND A HISTONE MODIFIER PAD4 IN MACROPHAGE EXTRACELLULAR TRAP FORMATION

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

DNA damage
DNA intercalator
small molecule
MAPK
mTOR
apoptosis
macrophage
extracellular traps
PAD4
citrullination
stroke

File:

Download Graduation_Thesis-Jinquan-20161201.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Zhi-Chun Lai, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Lu Bai, Committee Member
Robert Paulson, Outside Member