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11. The Role Of Sphingosine Kinase In The Crosstalk Between Apoptosis, Autophagy And Endocytosis

open_access
Open Access
Author:
Young, Megan Marie
Title:
The Role Of Sphingosine Kinase In The Crosstalk Between Apoptosis, Autophagy And Endocytosis
Graduate Program:
Pharmacology
Keywords:
autophagy
apoptosis
endocytosis
iDISC
sphingosine kinase
sphingosine
sphingolipid
SK1i
SKI-I
late endosome
File:
Download Thesis_Young_FINAL.pdf
Committee Members:
Hong Gang Wang, Dissertation Advisor/Co-Advisor
Hong Gang Wang, Committee Chair/Co-Chair
Mark Kester, Committee Chair/Co-Chair
Jin Ming Yang, Committee Member
Lisa M Shantz, Committee Member
Richard Robert Young, Committee Member

12. Anti-tumor effect and destabilization of mutant p53 by CB002, a p53-pathway restoring small molecule that stimulates autophagy

open_access
Open Access
Author:
Hernandez Borrero, Liz Janice
Title:
Anti-tumor effect and destabilization of mutant p53 by CB002, a p53-pathway restoring small molecule that stimulates autophagy
Graduate Program:
Biomedical Sciences
Keywords:
mutant p53
apoptosis
autophagy
p53 pathway restoration
small molecules
NOXA
File:
Download Masters_thesis_Liz_H._2016.pdf
Committee Members:
Wafik El-Deiry, Thesis Advisor/Co-Advisor
Scot R Kimball, Committee Member
Lisa M Shantz, Committee Member
Rosalyn Bryson Irby, Committee Member

14. A NOVEL SMALL MOLECULE DNA INTERCALATOR PZ1225 IN CANCER CELL APOPTOSIS AND A HISTONE MODIFIER PAD4 IN MACROPHAGE EXTRACELLULAR TRAP FORMATION

open_access
Open Access
Author:
sun, jinquan
Title:
A NOVEL SMALL MOLECULE DNA INTERCALATOR PZ1225 IN CANCER CELL APOPTOSIS AND A HISTONE MODIFIER PAD4 IN MACROPHAGE EXTRACELLULAR TRAP FORMATION
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
DNA damage
DNA intercalator
small molecule
MAPK
mTOR
apoptosis
macrophage
extracellular traps
PAD4
citrullination
stroke
File:
Download Graduation_Thesis-Jinquan-20161201.pdf
Committee Members:
Yanming Wang, Dissertation Advisor/Co-Advisor
Zhi-Chun Lai, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Lu Bai, Committee Member
Robert Paulson, Outside Member

15. THE FUNCTION AND REGULATION OF A TRANSCRIPTIONAL CO-ACTIVATOR YAP IN GROWTH CONTROL AND TISSUE HOMEOSTASIS

open_access
Open Access
Author:
Matsui, Yurika
Title:
THE FUNCTION AND REGULATION OF A TRANSCRIPTIONAL CO-ACTIVATOR YAP IN GROWTH CONTROL AND TISSUE HOMEOSTASIS
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
Hippo pathway
Yes-associated protein (YAP)
cell proliferation
apoptosis
isoform
pancreatic beta-cell
large tumor suppressor kinase 1 (LATS1)
File:
Download PhDdissertation_YurikaMatsui.pdf
Committee Members:
Zhi-Chun Lai, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Michael Axtell, Committee Member
Lorraine C Santy, Outside Member

16. ATG2-MEDIATED AUTOPHAGOSOME BIOGENESIS: MOLECULAR MECHANISM AND THERAPEUTIC IMPLICATIONS

open_access
Open Access
Author:
Tang, Zhenyuan
Title:
ATG2-MEDIATED AUTOPHAGOSOME BIOGENESIS: MOLECULAR MECHANISM AND THERAPEUTIC IMPLICATIONS
Graduate Program:
Biomedical Sciences
Keywords:
iDISC
Atg2
TOM40
MAM
mitochondira-associated ER membrane
mitochondira ER contact site
apoptosis
autophagy
File:
Download Zach_Thesis_FINAL.pdf
Committee Members:
Hong-Gang Wang, Dissertation Advisor/Co-Advisor
Hong-Gang Wang, Committee Chair/Co-Chair
Barbara Ann Miller, Committee Member
Rosalyn Bryson Irby, Committee Member
Richard Bernard Mailman, Outside Member
Yoshinori Takahashi, Committee Member