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Author:

Tamanaha, Esta Yuuka

Title:

Showcasing two C-h bond-cleaving manifolds through mechanistic studies of isopenicillin N synthase

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

IPNS
isopenicillin N synthase
ACV
ferryl
ferric-superoxide

File:

Download Esta_Dissertation-GradSchoolFinal5-CorrectedSubmission.pdf

Committee Members:

Joseph M Bollinger Jr., Dissertation Advisor/Co-Advisor
Carsten Krebs, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Member
Ming Tien, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Zaccardi, Margot Joan

Title:

mechanistic analysis of the tryptophan biosynthetic enzyme indole-3-glycerol phosphate synthase

Graduate Program:

Chemistry

Keywords:

indole-3-glycerol phosphate synthase
enzyme kinetics
mechanism of IGPS
thermophilic enzymes
enzyme engineering

File:

Download Zaccardi_Final.pdf

Committee Members:

David D Boehr, Dissertation Advisor/Co-Advisor
Scott A Showalter, Committee Chair/Co-Chair
Philip C. Bevilacqua, Committee Member
Craig Eugene Cameron, Special Member

Author:

Wilcox, Jennifer Lynn

Title:

Development and utilization of spectroscopic and chemical methodologies for investigating pKa shifting in nucleic acids

Graduate Program:

Chemistry

Keywords:

RNA
nucleic acids
2-aminopurine fluorescence
pKa shifting

File:

Download Wilcox_Thesis.pdf

Committee Members:

Philip C. Bevilacqua, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Member
Scott A Showalter, Committee Member
Andrey S Krasilnikov, Committee Member