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Author:

Hwang, Jungwook

Title:

BIOLOGICAL AND BIOCHEMICAL STUDIES OF HCV NS5A PROTEIN: FUNCTIONS IN GENOME REPLICATION AND ANTAGONISM OF THE INNATE IMMUNE RESPONSE

Graduate Program:

Integrative Biosciences

Keywords:

HCV
NS5A
PKA phosphorylation
RNA binding protein
PKR

File:

Download dissertation-Jungwook_Hwang.pdf

Committee Members:

Craig Eugene Cameron, Committee Chair/Co-Chair
Philip C. Bevilacqua, Committee Member
Harriet C Isom, Committee Member
Kouacou Konan, Committee Member
Joseph C. Reese, Committee Member

Author:

Schweiker, Katrina Lynn

Title:

Computational Design and Experimental Characterization of Proteins with Increased Stability and Solubility

Graduate Program:

Integrative Biosciences

Keywords:

protein stability
protein engineering
computational design
protein folding

File:

Download KLSfinal.pdf

Committee Members:

George Makhatadze, Dissertation Advisor/Co-Advisor
George I Makhatadze, Committee Chair/Co-Chair
Judith S Bond, Committee Member
Thomas E Spratt, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Veeraraghavan, Narayanan

Title:

CATALYTIC AND STRUCTURAL ROLES OF NUCLEOBASES AND METAL IONS IN SMALL RIBOZYMES: NEW INSIGHTS FROM CALCULATIONS AND COMPARISON TO EXPERIMENTS

Graduate Program:

Integrative Biosciences

Keywords:

NLPB
reverse GU wobble
wobble
ribozyme
RNA
molecular dynamics
HDV

File:

Download NVeeraraghavan-eTD.pdf

Committee Members:

Prof Sharon Hammes Schiffer, Dissertation Advisor/Co-Advisor
Philip C. Bevilacqua, Committee Chair/Co-Chair
Sharon Hammes Schiffer, Committee Chair/Co-Chair
William George Noid, Committee Member
Andrey S Krasilnikov, Committee Member
Reka Z Albert, Committee Member

Author:

Roy, Sunando

Title:

IDENTIFYING STRUCTURAL CHANGES IN EVOLVING VIRAL PROTEINS

Graduate Program:

Integrative Biosciences

Keywords:

Protein
Structure
Evolution
Adaptation
Viruses
Multivariate Statistics

File:

Download Thesis_Sunando_Roy_Final.pdf

Committee Members:

Mary Poss, Dissertation Advisor/Co-Advisor
Mary Poss, Committee Chair/Co-Chair
Francesca Chiaromonte, Committee Member
Ross Cameron Hardison, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Brown, Trevor S.

Title:

PROBLEM-ORIENTED INVESTIGATION OF THE pKa OF ACTIVE-SITE CYTOSINE 75 IN THE HEPATITIS DELTA VIRUS (HDV) RIBOZYME

Graduate Program:

Integrative Biosciences

Keywords:

31P NMR
hepatitis delta virus (HDV) ribozyme
Leadzyme
RNA folding
RNA structure
CD spectroscopy
UV spectroscopy and fluorescence spectroscopy

File:

Download Trevor_Brown_Thesis_print_for_GradSchool_4.pdf

Committee Members:

Philip C. Bevilacqua, Committee Chair/Co-Chair
Juliette T J Lecomte, Committee Chair/Co-Chair
Anne Milasincic Andrews, Committee Member
Stephen James Benkovic, Committee Member
Craig Eugene Cameron, Committee Member

Author:

Tang, Yin

Title:

HIDDEN RNA CODES REVEALED FROM THE PLANT IN VIVO RNA STRUCTUROME

Graduate Program:

Integrative Biosciences

Keywords:

RNA structure
Arabidopsis thaliana
oryza sativa
high-throughput sequencing

File:

No files available due to restrictions.

Committee Members:

Sarah M. Assmann, Dissertation Advisor/Co-Advisor
Sarah M. Assmann, Committee Chair/Co-Chair
Philip C. Bevilacqua, Committee Member
Anton Nekrutenko, Committee Member
Yu Zhang, Outside Member