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Author:

Szakal, Andrea

Title:

THE HEPATITIS DELTA VIRUS (HDV) RIBOZYME AS A MODEL FOR RNA CATALYSIS AND FOLDING

Graduate Program:

Chemistry

Keywords:

RNA folding
RNA catalysis

File:

Download Szakal_Doctoral_ThesisMaster_041508.pdf

Committee Members:

Sharon Hammes Schiffer, Committee Member
Christine Dolan Keating, Committee Member
Craig Eugene Cameron, Committee Member
Philip C. Bevilacqua, Committee Chair/Co-Chair

Author:

Dutta, Arnob

Title:

UNDERSTANDING HOW DHH1 AND CCR4-NOT COMPLEX REGULATE mRNA METABOLISM IN YEAST

Graduate Program:

Cell and Developmental Biology

Keywords:

transcription
mRNA

File:

Download Arnob_Dutta_PhD_thesis_PSU_Aug_2010.pdf

Committee Members:

Joseph C. Reese, Dissertation Advisor/Co-Advisor
Joseph C. Reese, Committee Chair/Co-Chair
David Scott Gilmour, Committee Member
Craig Eugene Cameron, Committee Member
Yanming Wang, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Oh, Hyung Suk

Title:

INSIGHT INTO POLIOVIRUS GENOME REPLICATION AND ENCAPSIDATION REVEALED FROM MOLECULAR CHARACTERIZATION OF 3B-3C CLEAVAGE SITE MUTANTS

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

cleavage site mutant
polyprotein processing
replication
poliovirus
complementation

File:

Download Oh_Dissertation_111809.pdf

Committee Members:

Craig Eugene Cameron, Dissertation Advisor/Co-Advisor
Craig Eugene Cameron, Committee Chair/Co-Chair
Kenneth Charles Keiler, Committee Member
B Tracy Nixon, Committee Member
Joseph C. Reese, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Hwang, Jungwook

Title:

BIOLOGICAL AND BIOCHEMICAL STUDIES OF HCV NS5A PROTEIN: FUNCTIONS IN GENOME REPLICATION AND ANTAGONISM OF THE INNATE IMMUNE RESPONSE

Graduate Program:

Integrative Biosciences

Keywords:

HCV
NS5A
PKA phosphorylation
RNA binding protein
PKR

File:

Download dissertation-Jungwook_Hwang.pdf

Committee Members:

Craig Eugene Cameron, Committee Chair/Co-Chair
Philip C. Bevilacqua, Committee Member
Harriet C Isom, Committee Member
Kouacou Konan, Committee Member
Joseph C. Reese, Committee Member

Author:

Toroney, Rebecca

Title:

Investigating Roles of Unconventional RNA Primary, Secondary, and Tertiary Motifs in Regulation of the Protein Kinase PKR

Graduate Program:

Chemistry

Keywords:

Hepatitis C Virus
RNA-protein interactions
IRES
PKR
innate immunity
triphosphate

File:

Download Toroney_R_Thesis.pdf

Committee Members:

Philip C. Bevilacqua, Dissertation Advisor/Co-Advisor
Philip C. Bevilacqua, Committee Chair/Co-Chair
Nicholas Winograd, Committee Member
Scott A Showalter, Committee Member
Craig Eugene Cameron, Committee Member

Author:

Hong, Sue-Jean

Title:

REGULATION AND PHYSIOLOGICAL ROLE OF SSRA RNA

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

SsrA
Caulobacter

File:

Download Thesis.pdf

Committee Members:

Kenneth Charles Keiler, Committee Chair/Co-Chair
Philip C. Bevilacqua, Committee Member
Craig Eugene Cameron, Committee Member
Wesley Tsoekjen Ng, Committee Member
B Tracy Nixon, Committee Member

Author:

Brown, Trevor S.

Title:

PROBLEM-ORIENTED INVESTIGATION OF THE pKa OF ACTIVE-SITE CYTOSINE 75 IN THE HEPATITIS DELTA VIRUS (HDV) RIBOZYME

Graduate Program:

Integrative Biosciences

Keywords:

31P NMR
hepatitis delta virus (HDV) ribozyme
Leadzyme
RNA folding
RNA structure
CD spectroscopy
UV spectroscopy and fluorescence spectroscopy

File:

Download Trevor_Brown_Thesis_print_for_GradSchool_4.pdf

Committee Members:

Philip C. Bevilacqua, Committee Chair/Co-Chair
Juliette T J Lecomte, Committee Chair/Co-Chair
Anne Milasincic Andrews, Committee Member
Stephen James Benkovic, Committee Member
Craig Eugene Cameron, Committee Member

Author:

Cordek, Daniel Girard

Title:

Regulation of hepatitis C virus NS5A protein function by host-mediated phosphorylation

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

hepatitis C virus
HCV
NS5A
phosphorylation
intrinsic disorder
IDP
RNA-binding

File:

Download Cordek_PhD_Dissertation_Dec_2012.pdf

Committee Members:

Craig Eugene Cameron, Dissertation Advisor/Co-Advisor
Craig Eugene Cameron, Committee Chair/Co-Chair
Paul Lee Babitzke, Committee Member
Philip C. Bevilacqua, Committee Member
Andrey S Krasilnikov, Committee Member
Lorraine C Santy, Committee Member

Author:

Zaccardi, Margot Joan

Title:

mechanistic analysis of the tryptophan biosynthetic enzyme indole-3-glycerol phosphate synthase

Graduate Program:

Chemistry

Keywords:

indole-3-glycerol phosphate synthase
enzyme kinetics
mechanism of IGPS
thermophilic enzymes
enzyme engineering

File:

Download Zaccardi_Final.pdf

Committee Members:

David D Boehr, Dissertation Advisor/Co-Advisor
Scott A Showalter, Committee Chair/Co-Chair
Philip C. Bevilacqua, Committee Member
Craig Eugene Cameron, Special Member

Author:

Hull, Chelsea Michelle

Title:

Mechanistic Investigation Of Activation Of The Innate Immune Sensor Pkr By Various Levels And Types Of Rna Structure

Graduate Program:

Chemistry

Keywords:

PKR
RNA
bacterial RNA
riboswitch
ribozyme
innate immunity

File:

Download Hull_CM_2016.pdf

Committee Members:

Philip C. Bevilacqua, Dissertation Advisor/Co-Advisor
Scott A Showalter, Committee Member
Christine Dolan Keating, Committee Member
Craig Eugene Cameron, Committee Member

Author:

Acevedo, Roderico

Title:

Investigation of protein-RNA interactions of the TAR-RNA-binding protein (TRBP)

Graduate Program:

Chemistry

Keywords:

Biophysics
Binding
TRBP
miRNA
RNAi

File:

Download Dissertation_RA.pdf

Committee Members:

Scott A Showalter, Dissertation Advisor/Co-Advisor
Philip C. Bevilacqua, Committee Member
Craig Eugene Cameron, Committee Member
Amie Kathleen Boal, Committee Member
Ken S Feldman, Special Member