Design and evaluation of porosity in 3D bone scaffold models-computational insights
Open Access
Author:
Dsa, Jonathan
Graduate Program:
Mechanical Engineering
Degree:
Master of Science
Document Type:
Master Thesis
Date of Defense:
June 17, 2024
Committee Members:
Sheikh Fahad Ferdous, Thesis Advisor/Co-Advisor Anilchandra Attaluri, Committee Member Brian Maicke, Professor in Charge/Director of Graduate Studies Ahm E Rahman, Committee Member
Keywords:
porosity 3d scaffold designs finite element analysis
Abstract:
Bones are important organs that provide support, facilitate movement, and protect internal organs. Many conditions, including osteoarthritis, osteomyelitis, osteoporosis, bone defects resulting from trauma and surgery, require the correct selection of bone. Traditional methods such as autologous bone grafting have limitations, which have led to the development of bone healing materials and methods. This study uses CAD-based methods and finite element analysis (FEA) to investigate the design, fabrication, and evaluation of bone scaffolds. Various scaffold designs were developed, and their mechanical properties and porosity were evaluated. This study highlights the importance of improving scaffold design to balance the artificial strength and biological activity required for good bone formation. The results show that the size of the strut can reduce porosity and compressive stress, while a larger area in the scaffold structure increases its resistance to compressive forces. These findings highlight the development of more effective bone repair solutions in orthopedic applications and suggest the development of better bone healing methods.
