Towards Portable Photoacoustic Imaging Device for Peripheral Arterial Disease
Open Access
Author:
Mitra, Mahaan
Graduate Program:
Electrical Engineering
Degree:
Master of Science
Document Type:
Master Thesis
Date of Defense:
November 07, 2022
Committee Members:
Sri-Rajasekhar Kothapalli, Thesis Advisor/Co-Advisor Zhiwen Liu, Committee Member Thomas La Porta, Program Head/Chair Tim Kane, Thesis Advisor/Co-Advisor
Keywords:
Medical Imaging Photoacoustic Imaging Vascular Imaging Ultrasound Transducer
Abstract:
Medical imaging modalities like ultrasound imaging and optical imaging emit non-ionizing radiations which make it an attractive choice for clinical imaging. Ultrasound imaging is known to image structural anatomies at deep depths. At the same time, optical imaging is known for a higher level of spatial contrast in imaging albeit at only superficial tissue depth. Photoacoustic imaging, discussed in greater detail later, combines the pros of both these modalities by imaging targets based on their optical properties. This ability of photoacoustic imaging consequently makes it possible to use it to image vasculature which ultrasound imaging might not be able to distinguish in tissue. The work presented in this thesis is done towards a portable and scalable photoacoustic imaging system for imaging deep human vasculature to detect peripheral arterial disease, a precursor of cerebral stroke and heart attack. The thesis delves into the transducers being fabricated towards this purpose, measuring signals from them and experiments including interfacing with a data acquisition platform, and image reconstruction from simulations mimicking the architecture of the transducers that are to be used.
