A Low-Cost Pulse Oximeter-Based Device for Monitoring Brain Dynamics
Open Access
- Author:
- Melnick, Chloe
- Graduate Program:
- Engineering Science and Mechanics
- Degree:
- Master of Science
- Document Type:
- Master Thesis
- Date of Defense:
- March 26, 2020
- Committee Members:
- Bruce Gluckman, Thesis Advisor/Co-Advisor
Patrick James Drew, Committee Member
Francesco Costanzo, Committee Member
Judith Todd Copley, Program Head/Chair - Keywords:
- Pulse oximetry
microcontroller
optical brain sensor
epilepsy
animal work
clinical work
Pulse oximetry
microcontroller
clinical work
Pulse oximetry
microcontroller
optical brain sensor
epilepsy
animal work
clinical work
animal work
cerebral oximetry
brain
brain monitoring
brain dynamics
Pulse oximetry
microcontroller
optical brain sensor
epilepsy
animal work
clinical work
epilepsy
optical brain sensor
oxygenation
oxygen sensing - Abstract:
- There is a growing need to understand the intrinsic activity of the brain, such as blood oxygen levels, hemodynamic tissue swelling, and neurovascular coupling. This thesis outlines the development of a pulse oximeter-based back-end device to help accomplish these brain measurements. The development of this device provides the opportunity for long term intrinsic optical measurements of brain activity to be made. The device may be useful for monitoring healthy brain activity in addition to performing neurological disease detection. This thesis outlines the hardware, firmware, and data processing used to develop this device. With the development of this device, an open-source pulse oximeter-based device for small-animals is now available. This device provides insight into future applications for open-source clinical recordings that can be used to treat and diagnose severe diseases. The implications of the device are explored in this paper, demonstrating its capability as a robust tool for measurement and diagnosis.