3D Reconstruction of 2D Endobronchial Ultrasound

Open Access
Breslav, Mikhail
Graduate Program:
Electrical Engineering
Master of Science
Document Type:
Master Thesis
Date of Defense:
June 21, 2010
Committee Members:
  • William Evan Higgins, Thesis Advisor
  • Vishal Monga, Thesis Advisor
  • 3D reconstruction
  • ultrasound
  • EBUS
The Multidimensional Image Processing Lab (MIPL) at The Pennsylvania State University has been developing methods to help stage and diagnose lung cancer for over 15 years now. MIPL has developed Multi Detector Computed Tomography based tools which help physicians navigate to regions of interest (ROIs). However, when an ROI is situated extraluminally to the airway walls, biopsies are performed essentially blindly. This is a result of the physician's inability to see the ROI, which can result in inadvertent puncturing of a blood vessel. Endobronchial Ultrasound (EBUS) is an imaging modality that provides live, in vivo, extraluminal views of biopsy sites. We explore the 3D reconstruction of 2D EBUS images as a possible solution. We develop the theory and practical considerations involved in 3D reconstruction. Then, we design and build three experiments in which an object is imaged through the controlled movement of an EBUS probe. 3D reconstructions are obtained for each of the three experiments and analyzed.