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Author:

Dang Do, An Ngoc

Title:

The eIF2 alpha Kinases GCN2 and PERK Regulate Phosphorylation of TOR Target Proteins and Differential Translation of mRNAs

Graduate Program:

Integrative Biosciences

Keywords:

2
cycloheximide
4-di-tert-butylhydroquinone
translation initiation
translation elongation
eIF2
eIF2B
4E-BP1
GCN2
p70S6K1
PERK
TOR
methionine deprivation
leucine deprivation
polysome
microarray
QRT-PCR
histidinol
leucinol
sucrose gradient
atf4
atf5
slc3a2
slc3a3
trfr
ldlr
stch
hspa5
igfbp-2

File:

Download An_Do_thesis_2008.pdf

Committee Members:

Leonard Shelton Jefferson Jr., Committee Chair/Co-Chair
Scot R Kimball, Committee Member
Ralph Lauren Keil, Committee Member
Douglas Cavener, Committee Member
Robert A Gabbay, Committee Member

Author:

Tuckow, Alexander Paul

Title:

CONTROL OF SKELETAL MUSCLE PROTEIN SYNTHESIS: FUNCTION AND REGULATION OF EUKARYOTIC INITIATION FACTOR 2B EPSILON

Graduate Program:

Physiology

Keywords:

translation initiation
protein synthesis
skeletal muscle

File:

Download Tuckow_Dissertation_FINAL.pdf

Committee Members:

Leonard Shelton Jefferson Jr., Dissertation Advisor/Co-Advisor
Leonard Shelton Jefferson Jr., Committee Chair/Co-Chair
Scot R Kimball, Committee Member
Charles H Lang, Committee Member
Lisa M Shantz, Committee Member
Willard M Freeman, Committee Member

Author:

Reis, Alexander

Title:

Sequence-Level Design of Evolutionary-Robust Genetic Systems

Graduate Program:

Chemical Engineering

Keywords:

synthetic biology
biophysics
CRISPR
genetic circuits
translation initiation

File:

Download Alex_Reis_Dissertation.pdf

Committee Members:

Howard M Salis, Dissertation Advisor/Co-Advisor
Howard M Salis, Committee Chair/Co-Chair
Phillip E Savage, Committee Member
Kristen Fichthorn, Committee Member
Philip C Bevilacqua, Outside Member
Phillip E Savage, Program Head/Chair