1. Advanced algorithms for the design and analysis of synthetic genetic parts Restricted (Penn State Only) Author: Hossain, Ayaan Title: Advanced algorithms for the design and analysis of synthetic genetic parts Graduate Program: Bioinformatics and Genomics (PhD) Keywords: automateddesignsyntheticgeneticpartscombinatorialoptimizationmachinelearningalgorithmpromotermRNAtranscriptiontranslationdecayrepressionCRISPRrepeatsinterferencegraphtheorypathfindingnonrepetitiverepetitivegenesynthesisassemblyoligopooldiscoverybarcodesprimerscountingNGSreadsclassifierclassificationregressorregressionrandomforestLASSOridgehomologousrecombinationinstabilitytuningefficiencyplasmidsgenomeengineeringdegenerateIUPACvertexcoverindependentsetinitiation File: Login to Download Committee Members: Paul Babitzke, Outside Unit MemberHoward Salis, Chair & Dissertation AdvisorCostas Maranas, Major Field MemberReka Albert, Outside Field MemberGeorge Perry, Program Head/Chair