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Author:

Schweiker, Katrina Lynn

Title:

Computational Design and Experimental Characterization of Proteins with Increased Stability and Solubility

Graduate Program:

Integrative Biosciences

Keywords:

protein stability
protein engineering
computational design
protein folding

File:

Download KLSfinal.pdf

Committee Members:

George Makhatadze, Dissertation Advisor/Co-Advisor
George I Makhatadze, Committee Chair/Co-Chair
Judith S Bond, Committee Member
Thomas E Spratt, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Huber-keener, Kathryn Joyce

Title:

Alterations In Gene Expression As A Response of Tumor Cells To Stresses

Graduate Program:

Pharmacology

Keywords:

eEF-2K
tamoxifen
glioma
breast cancer
protein synthesis
next generation-sequencing
protein stability

File:

Download Final_Thesis_Submission_to_School_7-1-12.pdf

Committee Members:

Jin Ming Yang, Dissertation Advisor/Co-Advisor
Robert G Levenson, Committee Member
Rongling Wu, Committee Member
Willard Freeman, Committee Member
Andrea Manni, Committee Member

Author:

Bui, Pho

Title:

Nonadditive Effects of Cosolvent Mixtures on Protein Stability in Aqueous Solutions

Graduate Program:

Chemistry

Keywords:

nonadditivity
ion specific effects
ion-pairing
cosolvent
protein stability
complex solutions
vibrational spectroscopy

File:

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Committee Members:

Paul Cremer, Chair & Dissertation Advisor
William Noid, Major Field Member
Tae-Hee Lee, Major Field Member
Lauren Zarzar, Major Field Member
Philip Bevilacqua, Program Head/Chair
Seong Kim, Outside Unit & Field Member

Author:

Mandalaparthy, Varun

Title:

The Influence of Cosolvent Interactions Upon Interfaces and Macromolecules

Graduate Program:

Chemistry

Keywords:

protein stability
polymers
proteins
osmolytes
thermodynamics
statistical mechanics
lattice models
protein folding
urea
tmao
simulations
theory
solute interactions
molecular dynamics
monte carlo

File:

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Committee Members:

Paul Cremer, Major Field Member
William Noid, Chair & Dissertation Advisor
Edward O'Brien, Major Field Member
Xiantao Li, Outside Unit & Field Member
Philip Bevilacqua, Program Head/Chair