1. understanding the fundamental principles behind the influences of native and non-native entanglements on protein structure, function, and misfolding Open Access Author: Sitarik, Ian Title: understanding the fundamental principles behind the influences of native and non-native entanglements on protein structure, function, and misfolding Graduate Program: Chemistry Keywords: Protein foldingprotein entanglementsprotein misfoldingsynonymous mutationsMD simulationsproteomicsnon-covalent lasso entanglements File: Download Ian_Sitarik_PennState_Thesis_v3.3.pdf Committee Members: William Noid, Major Field MemberArthur Lesk, Outside Unit & Field MemberMark Hedglin, Major Field MemberEdward O'Brien, Chair & Dissertation AdvisorKenneth Knappenberger, Program Head/Chair