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1. Evolution of components of gene regulation in Drosophila and mammals

open_access
Open Access
Author:
Dermitzakis, Emmanouil T
Title:
Evolution of components of gene regulation in Drosophila and mammals
Graduate Program:
Biology
Keywords:
transcirptional regulation
evolution
binding site turnover
promoter
File:
Download Dermitzakis-PHD-thesis-final.pdf
Committee Members:
Andrew G Clark, Committee Chair/Co-Chair
Hiroshi Akashi, Committee Member
Ross Cameron Hardison, Committee Member
Stephen Wade Schaeffer, Committee Member
Esther Siegfried, Committee Member

3. Advanced algorithms for the design and analysis of synthetic genetic parts

restricted_to_institution
Restricted (Penn State Only)
Author:
Hossain, Ayaan
Title:
Advanced algorithms for the design and analysis of synthetic genetic parts
Graduate Program:
Bioinformatics and Genomics (PhD)
Keywords:
automated
design
synthetic
genetic
parts
combinatorial
optimization
machine
learning
algorithm
promoter
mRNA
transcription
translation
decay
repression
CRISPR
repeats
interference
graph
theory
path
finding
nonrepetitive
repetitive
gene
synthesis
assembly
oligopool
discovery
barcodes
primers
counting
NGS
reads
classifier
classification
regressor
regression
random
forest
LASSO
ridge
homologous
recombination
instability
tuning
efficiency
plasmids
genome
engineering
degenerate
IUPAC
vertex
cover
independent
set
initiation
File:
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Committee Members:
Paul Babitzke, Outside Unit Member
Howard Salis, Chair & Dissertation Advisor
Costas Maranas, Major Field Member
Reka Albert, Outside Field Member
George Perry, Program Head/Chair