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1. The eIF2 alpha Kinases GCN2 and PERK Regulate Phosphorylation of TOR Target Proteins and Differential Translation of mRNAs

open_access
Open Access
Author:
Dang Do, An Ngoc
Title:
The eIF2 alpha Kinases GCN2 and PERK Regulate Phosphorylation of TOR Target Proteins and Differential Translation of mRNAs
Graduate Program:
Integrative Biosciences
Keywords:
2
cycloheximide
4-di-tert-butylhydroquinone
translation initiation
translation elongation
eIF2
eIF2B
4E-BP1
GCN2
p70S6K1
PERK
TOR
methionine deprivation
leucine deprivation
polysome
microarray
QRT-PCR
histidinol
leucinol
sucrose gradient
atf4
atf5
slc3a2
slc3a3
trfr
ldlr
stch
hspa5
igfbp-2
File:
Download An_Do_thesis_2008.pdf
Committee Members:
Leonard Shelton Jefferson Jr., Committee Chair/Co-Chair
Scot R Kimball, Committee Member
Ralph Lauren Keil, Committee Member
Douglas Cavener, Committee Member
Robert A Gabbay, Committee Member

2. The regulation of mTORC1 signaling in immobilized rat hindlimb skeletal muscle

open_access
Open Access
Author:
Kelleher, Andrew Ryan
Title:
The regulation of mTORC1 signaling in immobilized rat hindlimb skeletal muscle
Graduate Program:
Physiology
Keywords:
disuse atrophy
anabolic resistance
casting
REDD1
REDD2
Ddit4
Ddit4l
p70S6K1
muscle wasting
fixed muscle length
File:
Download Kelleher_AR.Doct_Dissertation_text.pdf
Committee Members:
Leonard Shelton Jefferson Jr., Dissertation Advisor/Co-Advisor
Scot R Kimball, Committee Member
Christopher Martin Yengo, Committee Member
Lisa M Shantz, Committee Member
Ian Alexander Simpson, Committee Member
Donald Leon Gill, Special Member