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Author:

Gandhi, Ujjawal Hitendra

Title:

The Role of Arachidonic Acid - Cyclooxygenase Pathway in the Anti-leukemic Properties of Selenium

Graduate Program:

Molecular Toxicology

Keywords:

Selenium
leukemia
15d-prostaglandin J2
gambogic acid
arachidonic acid
inflammation
leukemia stem cell
BCR-ABL
H-PGDS

File:

Download UHG_Thesis_FINAL.pdf

Committee Members:

Kumble Sandeep Prabhu, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Member
Dr Jack Vanden Heuvel, Committee Member
Shantu G Amin, Committee Member
Dr Ramesh Ramachandran, Committee Member

Author:

Olson, Thomas Lynn

Title:

Identification of Somatic Mutations in LGL Leukemia through Whole Genome Sequencing and Correlation of STAT3 Y640F Mutation with Treatment Response to Methotrexate.

Graduate Program:

Molecular Medicine

Keywords:

large granular lymphocytes
leukemia
STAT3
TBET
genomics

File:

Download Thomas_L_Olson.pdf

Committee Members:

"Thomas P Loughran, Jr", Dissertation Advisor/Co-Advisor
Rosalyn Bryson Irby, Committee Chair/Co-Chair
Thomas E Spratt, Committee Member
Richard James Courtney, Committee Member
Bruce A Stanley, Special Member

Author:

Finch, Emily Rebecca

Title:

The role of endogenous lipid mediators in models of experimental leukemia

Graduate Program:

Immunology and Infectious Diseases

Keywords:

NSAID
omega-3
leukemia stem cell
prostaglandin
cancer
leukemia
BCR-ABL

File:

Download Dissertation_EFINCH.pdf

Committee Members:

K. Sandeep Prabhu, Dissertation Advisor/Co-Advisor
Margherita T. Cantorna, Committee Chair/Co-Chair
Robert F. Paulson, Committee Member
Connie J. Rogers, Committee Member
Penny M. Kris-Etherton, Outside Member

Author:

Liu, Qiang

Title:

Autophagy and apoptosis in acute myeloid leukemia

Graduate Program:

Pharmacology

Keywords:

Bcl-2
Mcl-1
leukemia
autophagy
apoptosis
acute myeloid leukemia
small molecule inhibitors

File:

Download 2016-11-09_Thesis.pdf

Committee Members:

Hong-Gang Wang, Dissertation Advisor/Co-Advisor
Hong-Gang Wang, Committee Chair/Co-Chair
Jennifer Xavier, Committee Member
Shantu Amin, Committee Member
Qing Yang, Outside Member

Author:

Teye, Emmanuel Kwame

Title:

THE NOVEL MECHANISTIC ROLE OF PIGN IN LEUKEMIA PROGRESSION

Graduate Program:

Biomedical Sciences

Keywords:

myelodysplastic syndrome
acute myeloid leukemia
PIGN
chromosomal instability
risk-stratification
biomarker
spindle assembly checkpoint
leukemia
mitotic exit
GPI anchor biosynthesis
cancer
cell cycle
mitosis

File:

Download PS-Emmanuel_Kwame_Teye_Thesis.pdf

Committee Members:

Jeffrey J Pu, Dissertation Advisor/Co-Advisor
Jong Kak Yun, Committee Chair/Co-Chair
Hong-Gang Wang, Committee Member
Douglas B Stairs, Committee Member
Gregory Steven Yochum, Outside Member

Author:

Xu, Jie

Title:

From Structure Variation to Chromatin Spatial Reorganization, Uncovering the Genetic and Cis-regulatory Alteration in Primary Cancer Genomes

Graduate Program:

Biomedical Sciences

Keywords:

structure variants
cancer genome
chromatin structure
leukemia

File:

Download 0525.pdf

Committee Members:

Feng Yue, Dissertation Advisor/Co-Advisor
James Riley Broach, Committee Chair/Co-Chair
Zhonghua Gao, Committee Member
Hong-Gang Wang, Committee Member
Ross Cameron Hardison, Outside Member
Feng Yue, Committee Chair/Co-Chair
Barbara Ann Miller, Committee Member
Ralph Lauren Keil, Program Head/Chair

Author:

Qian, Fenghua

Title:

investigation of cyclopentenone prostaglandins and associated receptor GPR44 in acute myeloid leukemia

Graduate Program:

Pathobiology

Keywords:

leukemia
selenium
cyclopentenone prostaglandin
crth2
DP2
PPARγ
interleukin-4
androgen receptor
EPHA7
RTK
tumor microenvironment
leukemic stem cell

File:

No files available due to restrictions.

Committee Members:

Robert Paulson, Major Field Member
Kumble Prabhu, Chair & Dissertation Advisor
John Vanden Heuvel, Major Field Member
Anthony Paul Schmitt, Professor in Charge/Director of Graduate Studies
Vishal Singh, Outside Unit & Field Member