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Author:

Behan, Rachel Koren

Title:

SPECTROSCOPIC CHARACTERIZATION OF HIGH-VALENT INTERMEDIATES IN CYTOCHROME P450 AND OTHER HEME ENZYMES

Graduate Program:

Chemistry

Keywords:

ferryl
heme
cytochrome P450
peroxynitrite

File:

Download rkb_FinalThesis.pdf

Committee Members:

Michael Thomas Green, Committee Chair/Co-Chair
Joseph M Bollinger Jr., Committee Member
Carsten Krebs, Committee Member
Patrick Cirino, Committee Member

Author:

Tamanaha, Esta Yuuka

Title:

Showcasing two C-h bond-cleaving manifolds through mechanistic studies of isopenicillin N synthase

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

IPNS
isopenicillin N synthase
ACV
ferryl
ferric-superoxide

File:

Download Esta_Dissertation-GradSchoolFinal5-CorrectedSubmission.pdf

Committee Members:

Joseph M Bollinger Jr., Dissertation Advisor/Co-Advisor
Carsten Krebs, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Member
Ming Tien, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Vavra, Joseph

Title:

INVESTIGATIONS INTO THE DESATURATION OF AN ALIPHATIC SUBSTRATE BY CLAVAMINATE SYNTHASE

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology (MS)

Keywords:

Iron
2-oxoglutarate
clavaminic acid
ferryl
hydroxylation
desaturation
oxacyclization
hydrogen atom transfer

File:

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Committee Members:

Joseph M Bollinger, Jr., Thesis Advisor/Co-Advisor
Amie Kathleen Boal, Thesis Advisor/Co-Advisor
Ken Keiler, Professor in Charge/Director of Graduate Studies
Carsten Krebs, Thesis Advisor/Co-Advisor