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Author:

Wright, Ato Obrumah

Title:

ROLE OFCYLD, A DEUBIQUITINATING ENZYME, IN MAST CELL FUNCTION AND SPERMATOGENESIS

Graduate Program:

Cell and Molecular Biology

Keywords:

deubiquitination
K63
DUB
K48
Mast cells
FceRI
BMMC
degranulation
cytokines
type I allergy
allergy
IgE
tyrosine kinases
anaphylaxis
spermatogenesis
bcl-2
male infertility
germ cells
TNF-alpha
TRAF
LOH
loss of heterozygosity
ubiquitination
apoptosis
cylindromatosis
NF-kB
CYLD
RIP
Receptor interacting protein
caspase
IKK

File:

Download ATOWRIGHTthesis8-12-08.pdf

Committee Members:

Shao Cong Sun, Committee Chair/Co-Chair
Todd Schell, Committee Chair/Co-Chair
Robert Harold Bonneau, Committee Member
Neil David Christensen, Committee Member
Diane M Thiboutot, Committee Member

Author:

Miller, Jennifer Lynn

Title:

Phosphoproteomic Analysis of Ribosomal Proteins: Implications in Translation and Apoptosis

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

ribosomal proteins
apoptosis
phosphorylation
mitochondria
proteomics
translation

File:

Download FINAL_GRAD_SCHOOL.pdf

Committee Members:

Emine Koc, Dissertation Advisor/Co-Advisor
Ming Tien, Committee Member
Robert Allen Schlegel, Committee Member
Wendy Hanna Rose, Committee Member
Erin Elizabeth Sheets, Committee Member
Emine C Koc, Committee Chair/Co-Chair

Author:

Han, Min-Joon

Title:

MAMMALIAN MITOCHONDRIAL RIBOSOMAL PROTEINS : A MATTER OF LIFE AND DEATH

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

translation
mitochondria
apoptosis

File:

Download Min-Joon-upload-final.pdf

Committee Members:

Dr Emine Koc, Dissertation Advisor/Co-Advisor
Emine C Koc, Committee Chair/Co-Chair
Hasan Koc, Committee Chair/Co-Chair
Craig Eugene Cameron, Committee Member
Wendy Hanna Rose, Committee Member
Teh Hui Kao, Committee Member
Seogchan Kang, Committee Member

Author:

Cole, Sara L.

Title:

The DNA damage response of rodent fibroblasts expressing all or part of Simian Virus 40 large T antigen

Graduate Program:

Microbiology and Immunology

Keywords:

cell stress
Rb
Bcl-2
J-domain
SV40
5-fluorouracil
p53
apoptosis
DNA damage
large t antigen
transformation

File:

Download SColeThesis1201.pdf

Committee Members:

John Warren Wills, Committee Member
Anita Klein Hopper, Committee Member
Craig Matthew Meyers, Committee Member
Mary Judith Tevethia, Committee Chair/Co-Chair
Satvir Singh Tevethia, Committee Member

Author:

Fuentes, Sandra M

Title:

FUNCTIONS OF THE RESPIRATORY SYNCYTIAL VIRUS SH AND P PROTEINS

Graduate Program:

Pathobiology

Keywords:

apoptosis
small hydrophobic protein
RSV
AKT
P protein phosphorylation

File:

Download Fuentes_S_Dissertation_Final.pdf

Committee Members:

Biao He, Dissertation Advisor/Co-Advisor
Biao He, Committee Chair/Co-Chair
Anthony Paul Schmitt, Committee Chair/Co-Chair
Pamela Hankey Giblin, Committee Member
Michael N Teng, Committee Member
Avery August, Committee Member

Author:

Kivovich, Violetta

Title:

Examination of the mechanism of parvovirus B19 NS1 induced cellular toxicity.

Graduate Program:

Cell and Molecular Biology

Keywords:

homology modeling
B19
NS1
apoptosis
DNA damage
parvovirus
singla-strand breaks

File:

Download VKivovich_Thesis_Final.pdf

Committee Members:

Mark Kester, Ph D, Dissertation Advisor/Co-Advisor
Mark Kester, Committee Chair/Co-Chair
Stanley J Naides, Committee Member
Robert Harold Bonneau, Committee Member
Robert G Levenson, Committee Member
Leslie Joan Parent, Committee Member

Author:

Wang, Xibin

Title:

EFFECTS OF ZINC DEFICIENCY ON LONGITUDINAL BONE GROWTH IN JUVENILE CHICKENS AND YOUNG GROWING RATS

Graduate Program:

Nutrition

Keywords:

bone
zinc deficiency
cell proliferation
apoptosis
growth plate
in situ hybridization
immunohistochemistry

File:

Download etd.pdf

Committee Members:

Gary J Fosmire, Committee Member
Ronald Scott Kensinger, Committee Member
Sally E Johnson, Committee Member
Carol V Gay, Committee Member
Roland M Leach, Committee Chair/Co-Chair

Author:

Xu, Tongtong

Title:

Anti-Cancer Effects of Phenolic-rich Extracts of Button Mushrooms (Agaricus bisporus)

Graduate Program:

Food Science

Keywords:

Agaricus bisporus
mushrooms
cancer
phenolic compounds
apoptosis
microarray
SCID mice
xenograft tumor

File:

Download Final_dissertation_Tongtong_Xu_4-3-2013.pdf

Committee Members:

Joshua D Lambert, Dissertation Advisor/Co-Advisor
Robert Bruce Beelman, Committee Member
Ryan John Elias, Committee Member
John Patrick Vanden Heuvel, Committee Member

Author:

Lloyd, Shane

Title:

The Role of Connexin43 Gap Junction Protein in the Musculoskeletal Changes Induced by Mechanical Unloading

Graduate Program:

Cell and Molecular Biology

Keywords:

connexin43
unloading
bone loss
sclerostin
osteocyte
apoptosis
RANKL
muscle
spaceflight
atrophy
osteopenia

File:

Download Shane_Lloyd_PhD_Dissertation.pdf

Committee Members:

Henry Joseph Donahue, Dissertation Advisor/Co-Advisor
Henry Joseph Donahue, Committee Chair/Co-Chair
Charles H Lang, Committee Member
Neil Sharkey, Committee Member
James Robert Connor, Committee Member
Alicia Ellen Bateman, Special Member

Author:

Deng, Yaoting

Title:

Regulation of Hippo Signaling for Growth Control

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Hippo pathway
Hippo
transphosphorylation
dimerization
Merlin
Expanded
Kibra
FFA
β-cells
Yap
F-actin
apoptosis

File:

Download Dissertation_Yaoting_Deng.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Pamela Hankey Giblin, Committee Member
Richard W Ordway, Committee Member
Wendy Hanna Rose, Committee Member
Yanming Wang, Committee Member

Author:

Young, Megan Marie

Title:

The Role Of Sphingosine Kinase In The Crosstalk Between Apoptosis, Autophagy And Endocytosis

Graduate Program:

Pharmacology

Keywords:

autophagy
apoptosis
endocytosis
iDISC
sphingosine kinase
sphingosine
sphingolipid
SK1i
SKI-I
late endosome

File:

Download Thesis_Young_FINAL.pdf

Committee Members:

Hong Gang Wang, Dissertation Advisor/Co-Advisor
Hong Gang Wang, Committee Chair/Co-Chair
Mark Kester, Committee Chair/Co-Chair
Jin Ming Yang, Committee Member
Lisa M Shantz, Committee Member
Richard Robert Young, Committee Member

Author:

Hernandez Borrero, Liz Janice

Title:

Anti-tumor effect and destabilization of mutant p53 by CB002, a p53-pathway restoring small molecule that stimulates autophagy

Graduate Program:

Biomedical Sciences

Keywords:

mutant p53
apoptosis
autophagy
p53 pathway restoration
small molecules
NOXA

File:

Download Masters_thesis_Liz_H._2016.pdf

Committee Members:

Wafik El-Deiry, Thesis Advisor/Co-Advisor
Scot R Kimball, Committee Member
Lisa M Shantz, Committee Member
Rosalyn Bryson Irby, Committee Member

Author:

Liu, Qiang

Title:

Autophagy and apoptosis in acute myeloid leukemia

Graduate Program:

Pharmacology

Keywords:

Bcl-2
Mcl-1
leukemia
autophagy
apoptosis
acute myeloid leukemia
small molecule inhibitors

File:

Download 2016-11-09_Thesis.pdf

Committee Members:

Hong-Gang Wang, Dissertation Advisor/Co-Advisor
Hong-Gang Wang, Committee Chair/Co-Chair
Jennifer Xavier, Committee Member
Shantu Amin, Committee Member
Qing Yang, Outside Member

Author:

sun, jinquan

Title:

A NOVEL SMALL MOLECULE DNA INTERCALATOR PZ1225 IN CANCER CELL APOPTOSIS AND A HISTONE MODIFIER PAD4 IN MACROPHAGE EXTRACELLULAR TRAP FORMATION

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

DNA damage
DNA intercalator
small molecule
MAPK
mTOR
apoptosis
macrophage
extracellular traps
PAD4
citrullination
stroke

File:

Download Graduation_Thesis-Jinquan-20161201.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Zhi-Chun Lai, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Lu Bai, Committee Member
Robert Paulson, Outside Member

Author:

Matsui, Yurika

Title:

THE FUNCTION AND REGULATION OF A TRANSCRIPTIONAL CO-ACTIVATOR YAP IN GROWTH CONTROL AND TISSUE HOMEOSTASIS

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

Hippo pathway
Yes-associated protein (YAP)
cell proliferation
apoptosis
isoform
pancreatic beta-cell
large tumor suppressor kinase 1 (LATS1)

File:

Download PhDdissertation_YurikaMatsui.pdf

Committee Members:

Zhi-Chun Lai, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Michael Axtell, Committee Member
Lorraine C Santy, Outside Member

Author:

Tang, Zhenyuan

Title:

ATG2-MEDIATED AUTOPHAGOSOME BIOGENESIS: MOLECULAR MECHANISM AND THERAPEUTIC IMPLICATIONS

Graduate Program:

Biomedical Sciences

Keywords:

iDISC
Atg2
TOM40
MAM
mitochondira-associated ER membrane
mitochondira ER contact site
apoptosis
autophagy

File:

Download Zach_Thesis_FINAL.pdf

Committee Members:

Hong-Gang Wang, Dissertation Advisor/Co-Advisor
Hong-Gang Wang, Committee Chair/Co-Chair
Barbara Ann Miller, Committee Member
Rosalyn Bryson Irby, Committee Member
Richard Bernard Mailman, Outside Member
Yoshinori Takahashi, Committee Member

Author:

Zhang, Ruoheng

Title:

Schweinfurthins And Immunogenic Cell Death

Graduate Program:

Biomedical Sciences

Keywords:

Schweinfurthins
Immunogenic Cell Death (ICD)
calreticulin (CRT)
ER stress
apoptosis

File:

Download SCHWEINFURTHINS_AND_IMMUNOGENIC_CELL_DEATH.pdf

Committee Members:

Jong Yun, Major Field Member
Hong Zheng, Major Field Member
Todd Schell, Outside Unit & Field Member
Raymond Hohl, Chair & Dissertation Advisor
Jeffrey Neighbors, Major Field Member
Lisa Shantz, Program Head/Chair

Author:

Sankhe, Chinmay

Title:

Regulation of Epithelial-Mesenchymal Transition via Matrix Stiffness and Histone Methyltransferases

Graduate Program:

Chemical Engineering

Keywords:

Hyaluronic acid
atomic force microscopy
cytoskeleton
integrin-linked kinase
apoptosis
hydrogels
Hyaluronic Acid
Atomic Force Microscopy
Cytoskeleton
Apoptosis
Hydrogels
epigenetics
H3K9Me2
chromatin
Hippo Signaling
nuclear localization
biosensor

File:

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Committee Members:

Andrew Zydney, Major Field Member
Esther Gomez, Chair & Dissertation Advisor
Amir Sheikhi, Major Field Member
Sergei Grigoryev, Outside Unit & Field Member
Robert Rioux, Professor in Charge/Director of Graduate Studies