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Author:

Lugo, Alex J.

Title:

Biochemical Characterization of Dengue Non-structural Protein 5 (NS5) and General Acid Derivatives

Graduate Program:

Molecular Medicine

Keywords:

Dengue NS5
RNA-dependent RNA polymerase
Enzyme Kinetics

File:

Download Alex_Lugo-Thesis.pdf

Committee Members:

Craig Eugene Cameron, Thesis Advisor/Co-Advisor
Craig Eugene Cameron, Thesis Advisor/Co-Advisor

Author:

Harki, Daniel Allen

Title:

Chemical Synthesis of Base-Modified Ribonucleosides as Novel Antiviral Agents

Graduate Program:

Chemistry

Keywords:

universal base
coxsackievirus
poliovirus
lethal mutagenesis
RNA virus
RNA-dependent RNA polymerase
nucleotides
nucleosides
ribonucleosides
antiviral agents
nucleoside synthesis

File:

Download Harki_PhD_Thesis.pdf

Committee Members:

Blake Peterson, Committee Chair/Co-Chair
Craig Eugene Cameron, Committee Member
Ken S Feldman, Committee Member
Joseph M Bollinger Jr., Committee Member

Author:

Edathil, Jocelyn P

Title:

DESIGN, SYNTHESIS, ANTIVIRAL EVALUATION AND METABOLISM OF NUCLEOSIDE ANALOGS

Graduate Program:

Chemistry

Keywords:

nucleotides
universal base
poliovirus
lethal mutagenesis
nucleoside synthesis
RNA virus
nucleosides
RNA-dependent RNA polymerase
carbohydrate synthesis
nucleoside phosphorylation

File:

Download EdathilThesisFinal.pdf

Committee Members:

Blake R Peterson, Committee Chair/Co-Chair
Gong Chen, Committee Member
Craig Eugene Cameron, Committee Member
Anthony Edward Pegg, Committee Member

Author:

Korneeva, Victoria

Title:

POLIOVIRUS RNA-DEPENDENT RNA POLYMERASE (IN)FIDELITY: MECHANISMS, CONSEQUENCES AND APPLICATIONS

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

RNA-dependent RNA polymerase
fidelity
nucleotide selection
poliovirus

File:

Download KorneevaVictoriaPhDThesis.pdf

Committee Members:

Craig Eugene Cameron, Committee Chair/Co-Chair
Squire J Booker, Committee Member
Michael Teng, Committee Member
Ming Tien, Committee Member
Blake R Peterson, Committee Member