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Author:

Fazelinia, Hossein

Title:

COMPUTATIONAL DESIGN AND EXPERIMENTAL CHARACTERIZATION OF PROTEINS WITH NOVEL FUNCTIONS

Graduate Program:

Chemical Engineering

Keywords:

OptGraft
Protein engineering
Computational protein design
Enzyme cofactor alteration
IPRO

File:

Download Fazelinia_Dissertation.pdf

Committee Members:

Costas D Maranas, Dissertation Advisor/Co-Advisor
Costas D Maranas, Committee Chair/Co-Chair
Patrick Cirino, Committee Chair/Co-Chair
David D Boehr, Committee Member
Andrew Zydney, Committee Member

Author:

Grisewood, Matthew Jeffery

Title:

Development and Applications of Computational Enzyme Engineering Tools

Graduate Program:

Chemical Engineering

Keywords:

Iterative Protein Redesign and Optimization
IPRO
Computational
Enzyme
Redesign
Methyl-coenzyme M reductase
acyl-ACP thioesterase
Mcr
'TesA
OptZyme
Optimization
beta-glucuronidase
Protein engineering
Specificity
Activity

File:

Download MGrisewood_Dissertation.pdf

Committee Members:

Costas D Maranas, Dissertation Advisor/Co-Advisor
Costas D Maranas, Committee Chair/Co-Chair
Michael John Janik, Committee Member
Howard M Salis, Committee Member
James Gregory Ferry, Outside Member

Author:

Chen, Jiaxing

Title:

ENGINEERING A NON-COMMUTATIVE COMBINATORIAL PROTEIN LOGIC CIRCUIT TO CONTROL CELL ORIENTATION

Graduate Program:

Bioinformatics and Genomics (PhD)

Keywords:

Protein logic circuit
Synthetic biology
Protein engineering
Cell engineering
Src kinase
Chemogenetic
Optogenetic

File:

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Committee Members:

Dajiang Liu, Major Field Member
Scott Showalter, Outside Unit Member
Nikolay Dokholyan, Chair & Dissertation Advisor
Keith Cheng, Outside Field Member
David Koslicki, Program Head/Chair