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Author:

Kuzu, Omer Faruk

Title:

COMBINING PROTEOMICS and SYSTEMS BIOLOGY to IDENTIFY THEAPEUTIC TARGETS & PATHWAYS OF CANCER DRUGS

Graduate Program:

Genetics

Keywords:

Leelamine
Melanoma
Alox5

File:

Download thesis.pdf

Committee Members:

Gavin Peter Robertson, Thesis Advisor/Co-Advisor
Gavin Peter Robertson, Thesis Advisor/Co-Advisor
Jiyue Zhu, Thesis Advisor/Co-Advisor
Jin Ming Yang, Thesis Advisor/Co-Advisor
Philip Lazarus, Thesis Advisor/Co-Advisor

Author:

Chung, Chin-ying

Title:

Strategies to Overcome Drug Resistance in Melanoma

Graduate Program:

Molecular Toxicology

Keywords:

Melanoma
B-Raf(V600E)
Vemurafenib
Epigenetics
Cell invasion
Integrin

File:

Download Chin-Yingfinal_pdf.pdf

Committee Members:

Gavin Peter Robertson, Dissertation Advisor/Co-Advisor
Gavin Peter Robertson, Committee Chair/Co-Chair
Gary Alan Clawson, Committee Member
Rogerio I Neves, Special Member
Jiyue Zhu, Committee Member

Author:

Weston, Cody Lee

Title:

Understanding the role of HFE polymorphism in cancer

Graduate Program:

Neuroscience

Keywords:

Cancer
Iron
HFE
H67D
Melanoma
Mouse

File:

Download Thesis_Final__Repaired_.pdf

Committee Members:

James Robert Connor, Dissertation Advisor/Co-Advisor
James Robert Connor, Committee Chair/Co-Chair
Wafik El Deiry, Committee Member
Willard Freeman, Committee Member
Jennifer W Baccon, Committee Member

Author:

Kuzu, Omer Faruk

Title:

Lysosomotropic Cholesterol Transport Inhibitors as Potential Chemotherapeutic Agents

Graduate Program:

Genetics

Keywords:

Melanoma
tricyclic antidepressant
antipsychotic
FIASMA
lysosomotropic
intracellular cholesterol transport inhibitor

File:

Download Thesis_Last.pdf

Committee Members:

Gavin Peter Robertson, Dissertation Advisor/Co-Advisor
Robert G Levenson, Committee Member
Jin Ming Yang, Committee Member
Sinisa Dovat, Committee Member

Author:

Su, Yixue

Title:

Immune Cell-Mediated Biodegradable Theranostic Nanoparticles for Melanoma Targeting and Drug Delivery

Graduate Program:

Bioengineering

Keywords:

Nanoparticles
Immune cells
Theranostics
Melanoma
Drug Delivery

File:

Download Yixue_Su_Mater_Thesis_.pdf

Committee Members:

Jian Yang, Thesis Advisor/Co-Advisor
Justin Lee Brown, Thesis Advisor/Co-Advisor
Yong Wang, Thesis Advisor/Co-Advisor

Author:

Johnson, Hannah

Title:

Discovery of Novel Small Molecule Activators of Protein Phosphatase 2A (PP2A) in the Treatment of Cancer

Graduate Program:

Biomedical Sciences

Keywords:

PP2A
Activators
Cancer
Therapeutics
Colorectal Cancer
Melanoma

File:

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Committee Members:

Lisa Shantz, Program Head/Chair
Vladimir Spiegelman, Outside Field Member
Arun Sharma, Chair & Dissertation Advisor
Gail Matters, Major Field Member
Junxuan Lu, Major Field Member
Todd Schell, Outside Unit Member
Satya Narayan, Special Member