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Author:

Veeraraghavan, Narayanan

Title:

CATALYTIC AND STRUCTURAL ROLES OF NUCLEOBASES AND METAL IONS IN SMALL RIBOZYMES: NEW INSIGHTS FROM CALCULATIONS AND COMPARISON TO EXPERIMENTS

Graduate Program:

Integrative Biosciences

Keywords:

NLPB
reverse GU wobble
wobble
ribozyme
RNA
molecular dynamics
HDV

File:

Download NVeeraraghavan-eTD.pdf

Committee Members:

Prof Sharon Hammes Schiffer, Dissertation Advisor/Co-Advisor
Philip C. Bevilacqua, Committee Chair/Co-Chair
Sharon Hammes Schiffer, Committee Chair/Co-Chair
William George Noid, Committee Member
Andrey S Krasilnikov, Committee Member
Reka Z Albert, Committee Member

Author:

Thaplyal, Pallavi

Title:

Investigations of the Mechanistic Pathways of the Hepatitis Delta Virus Ribozyme

Graduate Program:

Chemistry

Keywords:

Ribozyme
Kinetics
HDV
pKa
QM/MM
Thio Effects
Metal Ion Rescue

File:

Download Thesis_PTFinal.pdf

Committee Members:

Philip C. Bevilacqua, Dissertation Advisor/Co-Advisor
Philip C. Bevilacqua, Committee Chair/Co-Chair
Squire J Booker, Committee Member
Lasse Jensen, Committee Member
Katsuhiko Murakami, Special Member