Search

Author:

Lazzaro, Brian Paul

Title:

A population and quantitative genetic analysis of the Drosophila melanogaster antibacterial immune response

Graduate Program:

Biology

Keywords:

Drosophila melanogaster
population genetics
quantitative genetics
innate immunity
antibacterial
SNP
association study
pathogen
bacteria

File:

Download thesis.PDF

Committee Members:

Stephen Wade Schaeffer, Committee Chair/Co-Chair
Thomas Whittam, Committee Member
Andrew Clark, Committee Chair/Co-Chair
Hiroshi Akashi, Committee Member
Diana Lynn Cox Foster, Committee Member

Author:

Rizkalla, Hany Waheeb

Title:

The Role of the Wingless Signaling Pathway in Cell Fate Specification

Graduate Program:

Biology

Keywords:

somatic mesoderm
signal transduction
Wnt
Wingless signaling
Drosophila melanogaster
myogenesis
cell specification
founder cell
Zeste white 3
GSK-3

File:

Download HWR_PhD_Thesis.pdf

Committee Members:

Esther Siegfried, Committee Chair/Co-Chair
David Scott Gilmour, Committee Member
Richard W Ordway, Committee Member
Stephen Wade Schaeffer, Committee Member

Author:

Iyer, Janani

Title:

Genetic Analysis of Synaptic Transmission

Graduate Program:

Genetics

Keywords:

Genetic Analysis
Synaptic Transmission
Drosophila melanogaster
Neurotransmission

File:

Download Janani_Iyer_Dissertation.pdfDownload Proquest_Agreement.pdfDownload doctoral_approval_page001.pdfDownload eTD_approval_form002.pdfDownload Survey_of_earned_doctorates_005.pdf

Committee Members:

Fumiko Kawasaki, Dissertation Advisor/Co-Advisor
Richard W Ordway, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Wendy Hanna Rose, Committee Member

Author:

Wang, Qingyu

Title:

Evaluation of whole exome sequencing technology in cohort dataset and quantification of phenotypic alterations in a model organism

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

Whole Exome Sequencing
low coverage
unevenness
Drosophila melanogaster
eye phenotype
image processing
quantitative assessment

File:

Download QWFinal_dissertation.pdf

Committee Members:

Naomi S Altman, Dissertation Advisor/Co-Advisor
Santhosh Girirajan, Dissertation Advisor/Co-Advisor
Ross Cameron Hardison, Committee Member
Shaun A Mahony, Committee Member
Cooduvalli S Shashikant, Committee Member

Author:

Reynolds, Claire Elizabeth

Title:

Identification of Genetic Factors That Affect Neuronal Patterning, Function, and Disease in Drosophila Melanogaster

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Autophagy
Neurodegenerative Disease
Drosophila melanogaster
Proteoglycan
Heparan Sulfate
Multiple Sulfatase Deficiency
Drosophila behavior
Behavioral screening
Alzheimer's disease
Mucopolysaccharidosis
Neuromuscular Junction

File:

Download CR-thesis-Final-final.pdf

Committee Members:

Scott Brian Selleck, Dissertation Advisor/Co-Advisor
Scott Brian Selleck, Committee Chair/Co-Chair
Joseph C. Reese, Committee Member
Santhosh Girirajan, Committee Member
Richard W Ordway, Outside Member
Marylyn Deriggi Ritchie, Committee Member

Author:

Deal, Jack

Title:

Modeling the Dynamics of Elk Subfamily Ion Channels for Physiological Modulation

Graduate Program:

Bioengineering

Keywords:

Elk
Voltage-gated ion channels
Potassium channels
Drosophila melanogaster
Xenopus
Kinetic model
Fluorescent Microscopy
Ankyrin
Axon Initial Segment
Boltzmann
Heme

File:

Download MODELING_THE_DYNAMICS_OF_ELK_SUBFAMILY_ION_CHANNELS_FOR_PHYSIOLOGICAL_MODULATION.pdf

Committee Members:

Timothy J Jegla, Thesis Advisor/Co-Advisor
William O Hancock, Program Head/Chair
William O Hancock, Committee Member
Justin Lee Brown, Committee Member

Author:

Jensen, Matthew

Title:

Complex genetic interaction patterns determine the phenotypic trajectory of neurodevelopmental disorders

Graduate Program:

Bioinformatics and Genomics (PhD)

Keywords:

Neurodevelopmental disorders
Copy-number variants
Genomics
Transcriptomics
Drosophila melanogaster
Whole genome sequencing
Network analysis

File:

Download Matthew_Jensen_dissertation.pdf

Committee Members:

Dajiang Liu, Outside Unit & Field Member
Ross Hardison, Major Field Member
Santhosh Girirajan, Chair & Dissertation Advisor
Reka Albert, Major Field Member
George Perry, Program Head/Chair

Author:

Ingraham, Phoebe

Title:

Assessment of Sex-biased Phenotypic Patterns in Drosophila Homologs of Neurodevelopmental Disease-associated Genes

Graduate Program:

Molecular, Cellular, and Integrative Biosciences

Keywords:

Drosophila melanogaster
Sex-bias
Neurodevelopment
Genetics
Genetic interaction
CNVs
Genetic models
Neurodevelopmental disease

File:

Download Thesis_PMI_06.25.2021.pdf

Committee Members:

Melissa Rolls, Program Head/Chair
Santhosh Girirajan, Thesis Advisor/Co-Advisor
Stephen Wade Schaeffer, Committee Member
Laura Carrel, Committee Member

Author:

Govindarajan, Maalavika

Title:

Mechanisms that influence microtubule nucleation machinery localization in Drosophila melanogaster dendritic branchpoints

Graduate Program:

Neuroscience

Keywords:

microtubule
nucleation
Drosophila melanogaster
neurons
dendritic branchpoints
cytoskeleton
cell biology
confocal microscopy

File:

Download MS_Thesis-_PSU-Final-_Maalavika_Govindarajan.pdf

Committee Members:

Melissa Rolls, Thesis Advisor/Co-Advisor
Aimin Liu, Committee Member
Sonia Cavigelli, Professor in Charge/Director of Graduate Studies
William O Hancock, Committee Member

Author:

Kulkarni, Yash

Title:

Uncovering the mechanism of small molecule RAA-47 in ALS

Graduate Program:

Neuroscience

Keywords:

ALS
TDP-43
small molecule
Spermidine synthase
stress granule
Drosophila melanogaster

File:

No files available due to restrictions.

Committee Members:

Daniela Zarnescu, Thesis Advisor/Co-Advisor
Anirban Paul, Committee Member
Alistair Barber, Program Head/Chair
Wesley M Raup-Konsavage, Committee Member