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1. Development of Ultrafiltration and Diafiltration Processes for Batch and Continuous Formulation of Monoclonal Antibodies

open_access
Open Access
Author:
Jabra, Mario
Title:
Development of Ultrafiltration and Diafiltration Processes for Batch and Continuous Formulation of Monoclonal Antibodies
Graduate Program:
Chemical Engineering (PHD)
Keywords:
Ultrafiltration
Diafiltration
Continuous
Multistage countercurrent
pH shift
Excipient Shift
Bioprocessing
membrane filtration
Single Pass tangential flow filtration
SPTFF
Mechanistic Modelling
SPTFF optimization
Buffer Exchange
Countercurrent Dialysis
Continuous Ultrafiltration
Continuous Diafiltration
Membrane Processing
Monoclonal Antibody
IgG
Therapeutic Protein
Formulation
File:
Download Final_Thesis_by_Mario_Jabra.pdf
Committee Members:
Andrew Zydney, Chair & Dissertation Advisor
William Hancock, Outside Unit & Field Member
Wayne Curtis, Major Field Member
Darrell Velegol, Major Field Member
Seong H. Kim, Professor in Charge/Director of Graduate Studies

2. The Novel Exploration And Development of Single-use, Single-pass Continuous Downstream Bioprocessing Technologies Using Hollow Fiber Membranes

open_access
Open Access
Author:
Yehl, Christopher
Title:
The Novel Exploration And Development of Single-use, Single-pass Continuous Downstream Bioprocessing Technologies Using Hollow Fiber Membranes
Graduate Program:
Chemical Engineering (PHD)
Keywords:
Biotherapeutics
Downstream Processing
Hollow Fibers
Continuous Processing
Single-use
Single-Pass
Ultrafiltration
Diafiltration
Countercurrent Dialysis
Monoclonal Antibodies
High Performance Countercurrent Membrane Purification
Hollow Fiber Characterization
Hollow Fiber Modification
File:
Download Dissertation_2021_11_05_CJY.pdf
Committee Members:
Andrew Zydney, Chair & Dissertation Advisor
William Hancock, Outside Unit & Field Member
Esther Gomez, Major Field Member
Stephanie Velegol, Major Field Member
Seong Han Kim, Professor in Charge/Director of Graduate Studies