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Author:

Watson, Alan Michael

Title:

PEPTIDE-MHC-STABILITY DETERMINES THE SIZE OF THE CD8+ T CELL RESPONSE TOWARD AN IMMUNORECESSIVE TUMOR ANTIGEN DETERMINANT

Graduate Program:

Microbiology and Immunology

Keywords:

Antigen Presentation
Cross-Priming
Peptide MHC Stability
Peptide
T cell
SV40 T Antigen
Tumor
Cancer
Mouse

File:

Download AlanWatson_eTD_Submitted.pdf

Committee Members:

Todd Schell, Dissertation Advisor/Co-Advisor
Todd Schell, Committee Chair/Co-Chair
Neil David Christensen, Committee Member
David Joseph Spector, Committee Member
Mary E Truckenmiller, Committee Member
Ronald Paul Wilson, Committee Member

Author:

Punekar, Rajeshwari S

Title:

MENTAL HEALTH, AMBULATORY MENTAL HEALTH VISITS, AND PSYCHOTHERAPEUTIC MEDICATIONS OF U.S. CANCER SURVIVORS AND THEIR SPOUSES

Graduate Program:

Health Policy and Administration

Keywords:

Cancer Survivors
Cancer
Psychotherapeutic Medications
Ambulatory Mental Health Visits
Mental Health

File:

Download Thesis__with_CV_.pdf

Committee Members:

Pamela Farley Short, Dissertation Advisor/Co-Advisor
Pamela Farley Short, Committee Chair/Co-Chair
John Raymond Moran Jr., Committee Member
Marianne Messersmith Hillemeier, Committee Member
Elana Farace, Committee Member

Author:

Ali-rahmani, Fatima Ghazanfar

Title:

HFE GENE VARIANTS AND DYSREGULATION OF CHOLESTEROL AND IRON METABOLISM IN ALZHEIMER DISEASE AND CANCER

Graduate Program:

Molecular Medicine

Keywords:

Iron
HFE
Cholesterol
Alzheimer disease
Cancer
mouse model

File:

Download Ali-Rahmani_Fatima-Thesis-Final.pdf

Committee Members:

James Robert Connor, Dissertation Advisor/Co-Advisor
Cara Lynne Schengrund, Dissertation Advisor/Co-Advisor
Ian Alexander Simpson, Committee Member
Patricia Sue Grigson, Committee Member
Jong Kak Yun, Committee Member

Author:

Weston, Cody Lee

Title:

Understanding the role of HFE polymorphism in cancer

Graduate Program:

Neuroscience

Keywords:

Cancer
Iron
HFE
H67D
Melanoma
Mouse

File:

Download Thesis_Final__Repaired_.pdf

Committee Members:

James Robert Connor, Dissertation Advisor/Co-Advisor
James Robert Connor, Committee Chair/Co-Chair
Wafik El Deiry, Committee Member
Willard Freeman, Committee Member
Jennifer W Baccon, Committee Member

Author:

Stewart, Renee Ruth

Title:

An Analysis of Recruitment for a Non-treatment Based Advance Care Planning Research Study in Terminal Cancer Patients

Graduate Program:

Public Health Sciences

Keywords:

Recruitment
Advance Care Planning
End of Life
Cancer
non-treatment

File:

Download RStewartThesisMSPHS.pdf

Committee Members:

Benjamin H Levi, Thesis Advisor/Co-Advisor
Michael Jay Green, Thesis Advisor/Co-Advisor
Jane Ruth Schubart, Thesis Advisor/Co-Advisor
Elana Farace, Thesis Advisor/Co-Advisor
Chengwu Yang, Thesis Advisor/Co-Advisor

Author:

Ward-kavanagh, Lindsay Kate

Title:

The broad applicability of adoptive immunotherapy in cancer: optimization through host conditioning and target selection

Graduate Program:

Cell and Molecular Biology

Keywords:

Immunotherapy
Cancer
Adoptive Cell Therapy
Radiation
Anti-CD40
Conditioning
SV40 T Antigen
CD8+ T cell

File:

Download WardKavanaghDissertation.pdf

Committee Members:

Todd Schell, Dissertation Advisor/Co-Advisor
Todd Schell, Committee Chair/Co-Chair
Kristin Ann Eckert, Committee Member
Christopher Charles Norbury, Committee Member
Clare E Sample, Committee Member
Jianxun Song, Committee Member

Author:

Gomez Tejeda Zanudo, Jorge

Title:

Network-based dynamic modeling and control strategies in complex diseases

Graduate Program:

Physics

Keywords:

Systems Biology
Complex Networks
Network models
Cancer

File:

Download Dissertation-JGTZanudo-Final.pdf

Committee Members:

Reka Z Albert, Dissertation Advisor/Co-Advisor
Reka Z Albert, Committee Chair/Co-Chair
Dezhe Jin, Committee Member
Lu Bai, Committee Member
Timothy Reluga, Committee Member
Richard Wallace Robinett, Special Member

Author:

Keller, Ross Richard

Title:

Elucidating Evolutionary Constraints of Mouse Mammary Cancer Using Adenomatous Polyposis Coli Mutations

Graduate Program:

Biomedical Sciences

Keywords:

Cancer
Evolution
Genetics

File:

Download Keller_Dissertation.pdf

Committee Members:

Edward Joseph Gunther, Dissertation Advisor/Co-Advisor
Edward Joseph Gunther, Committee Chair/Co-Chair
Kristin Ann Eckert, Committee Member
Lisa M Shantz, Committee Member
James Riley Broach, Outside Member
Sarah Bronson, Committee Member

Author:

Daniels, Silvano Rakeem

Title:

THE ROLE OF LOSS-OF-FUNCTION CBL-C MUTATIONS IN SOLID TUMORS

Graduate Program:

Biomedical Sciences

Keywords:

Cbl
Cbl-c
EGFR
Cancer
Receptor Tyrosine Kinase
RTK
Ubiquitin Ligase
E3
Ubiquitin
RING

File:

Download FINAL_PSU_Masters_Thesis__Rakeem_Daniels_2018___EDITED.pdf

Committee Members:

Lisa M Shantz, Thesis Advisor/Co-Advisor
Edward Joseph Gunther, Committee Member
Sheldon L Holder, Committee Member
Irina A Elcheva, Committee Member
Stanley Lipkowitz, Thesis Advisor/Co-Advisor

Author:

Doosthosseini, Mahsa

Title:

On the Accuracy of Drug-Resistant Cell Population Estimation from Total Cancer Size Measurements

Graduate Program:

Mechanical Engineering

Keywords:

Cancer
Drug-Resistant
Fisher Information Matrix
CRLB
Parameter Estimation Accuracy

File:

Download Mahsa_Master_Thesis_2019_Final__2_.pdf

Committee Members:

Hosam K. Fathy, Thesis Advisor/Co-Advisor
Christopher Rahn, Committee Member

Author:

Xia, Yiqiu

Title:

MICROFLUIDIC PLATFORMS TOWARDS VIRUS DETECTION AND CANCER DIAGNOSIS BASED ON TUMOR CELLS

Graduate Program:

Bioengineering

Keywords:

Microfluidic
Diagnosis
Cancer
Virus detection

File:

Download Dissertation_Yiqiu.pdf

Committee Members:

Siyang Zheng, Dissertation Advisor/Co-Advisor
Siyang Zheng, Committee Chair/Co-Chair
Yong Wang, Committee Member
Xiaojun Lance Lian, Committee Member
Huaguang Lu, Outside Member

Author:

Clayman, Carly

Title:

RNA Sequencing and Clinical Data Analysis of Multiple Cancer Types on the National Cancer Institute's Genomic Data Commons

Graduate Program:

Engineering Science

Keywords:

RNA Sequencing
Genomic Data Commons
TCGA
Prostate Cancer
Survival Analysis
Boruta Random Forest
Feature Selection
Clustering Analysis
Principal Component Analysis
Clinical Data
RNA-Seq
Cancer
Landmark Genes

File:

Download MS_Thesis_Clayman_2019.pdf

Committee Members:

Satish Mahadevan Srinivasan, Thesis Advisor/Co-Advisor
Raghu Sangwan, Committee Member
Youakim Badr, Committee Member
Colin Neill, Program Head/Chair

Author:

Sundberg, Kyle

Title:

Targeting pro-survival protein Mcl-1 in cancer cells by activating an alternative proteasomal degradation pathway

Graduate Program:

Biomedical Sciences

Keywords:

Mcl-1
MCL!
Cancer
Cancer therapeutics
proteasome
cancer metabolism
mitochondria

File:

Download Kyle_Sundberg_s_Masters_Thesis_-_FINAL.pdf

Committee Members:

Hong-Gang Wang, Thesis Advisor/Co-Advisor
George Lucian Moldovan, Committee Member
Barbara Ann Miller, Committee Member
David James Degraff, Committee Member
Ralph Lauren Keil, Program Head/Chair

Author:

Vilchez Mercedes, Samuel

Title:

The Role of NRF2 in Collective Cancer Invasion

Graduate Program:

Bioengineering

Keywords:

Hybrid E/M
Cancer
Bladder Cancer
Notch signaling
Leader cells
EMT
Collective Migration
NRF2

File:

Download SV_Dissertation_final_noBoxes.pdf

Committee Members:

Peter Butler, Major Field Member
Yong Wang, Major Field Member
Zhi-Chun Lai, Outside Unit & Field Member
Daniel Hayes, Program Head/Chair
Pak Kin Wong, Chair & Dissertation Advisor

Author:

Ba, Djibril

Title:

Association of mushroom consumption with major chronic diseases and mortality

Graduate Program:

Epidemiology (PhD)

Keywords:

Mushrooms
Cancer
Mortality
Cardiometabolic Diseases
Depression
Epidemiology
NHANES

File:

Download PhD_EPI_Final_Dissertation_Djibril_M_Ba.pdf

Committee Members:

Xiang Gao, Outside Unit & Field Member
Laila Al-Shaar, Major Field Member
Vernon Chinchilli, Major Field Member
Joshua Muscat, Dissertation Advisor
John Richie, Chair of Committee
Douglas Leslie, Program Head/Chair

Author:

Lesko, Elizabeth

Title:

An Investigation of the Spontaneous Regression of Chemically-Induced Neoplastic Skin Lesions in Mice Lacking Autoimmune Regulator

Graduate Program:

Biomedical Sciences

Keywords:

Autoimmune Regulator
Non-melanoma skin cancer
Squamous Cell Carcinoma
Mouse model
Cancer
Regression
Chemical carcinogenesis

File:

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Committee Members:

Ryan Hobbs, Thesis Advisor/Co-Advisor
Amanda Marie Nelson, Committee Member
Ralph Keil, Program Head/Chair
Lisa M Shantz, Thesis Advisor/Co-Advisor
Christopher Charles Norbury, Committee Member

Author:

Johnson, Hannah

Title:

Discovery of Novel Small Molecule Activators of Protein Phosphatase 2A (PP2A) in the Treatment of Cancer

Graduate Program:

Biomedical Sciences

Keywords:

PP2A
Activators
Cancer
Therapeutics
Colorectal Cancer
Melanoma

File:

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Committee Members:

Lisa Shantz, Program Head/Chair
Vladimir Spiegelman, Outside Field Member
Arun Sharma, Chair & Dissertation Advisor
Gail Matters, Major Field Member
Junxuan Lu, Major Field Member
Todd Schell, Outside Unit Member
Satya Narayan, Special Member

Author:

Pale, Lindsey

Title:

Identifying Novel Factors Involved in Cancer Therapy Sensitivity and Resistance using Genome-Wide CRISPR Screens

Graduate Program:

Biomedical Sciences

Keywords:

CRISPR
DNA Repair
DNA Damage
Cancer
BRCA
Cisplatin
PARP Inhibitor
PRIMPOL

File:

Login to Download

Committee Members:

James Broach, Major Field Member
Zhonghua Gao, Major Field Member
George Moldovan, Chair & Dissertation Advisor
Lisa Shantz, Program Head/Chair
Lisa Shantz, Outside Unit & Field Member