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Author:

Chapman, Brittany

Title:

Evaluation of CRISPR-Based Approaches for Precision Poultry Gene Modulation and Delivery

Graduate Program:

Animal Science

Keywords:

CRISPR
Gene Editing
ReMOT
CRISPRa/i
dCas9
QVtg

File:

Download B._Chapman___Master_s_Thesis.pdf

Committee Members:

Tae Hyun Kim, Thesis Advisor/Co-Advisor
Jason Laurence Rasgon, Committee Member
Adele Turzillo, Program Head/Chair
Francisco Javier Diaz, Committee Member

Author:

Shih, Justin

Title:

Precise Genome Editing in Oryza Sativa and Magnaporthe Oryzae

Graduate Program:

Plant Pathology

Keywords:

genome editing
CRISPR
plant genetics
crop improvement
rice
HDR
base editing
prime editing
rice blast

File:

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Committee Members:

Cristina Rosa, Major Field Member
Timothy Mcnellis, Major Field Member
Claude Depamphilis, Outside Unit & Field Member
Yinong Yang, Chair & Dissertation Advisor
Maria Del Mar Jimenez Gasco, Program Head/Chair

Author:

Hossain, Ayaan

Title:

Advanced algorithms for the design and analysis of synthetic genetic parts

Graduate Program:

Bioinformatics and Genomics (PhD)

Keywords:

automated
design
synthetic
genetic
parts
combinatorial
optimization
machine
learning
algorithm
promoter
mRNA
transcription
translation
decay
repression
CRISPR
repeats
interference
graph
theory
path
finding
nonrepetitive
repetitive
gene
synthesis
assembly
oligopool
discovery
barcodes
primers
counting
NGS
reads
classifier
classification
regressor
regression
random
forest
LASSO
ridge
homologous
recombination
instability
tuning
efficiency
plasmids
genome
engineering
degenerate
IUPAC
vertex
cover
independent
set
initiation

File:

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Committee Members:

Paul Babitzke, Outside Unit Member
Howard Salis, Chair & Dissertation Advisor
Costas Maranas, Major Field Member
Reka Albert, Outside Field Member
George Perry, Program Head/Chair

Author:

O'Connor, Michael

Title:

PARP14 regulates cyclin D1 expression to promote cell cycle progression

Graduate Program:

Biomedical Sciences

Keywords:

cell cycle
cyclin D1
CDK4/6 inhibitors
CRISPR
PARP14
breast cancer

File:

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Committee Members:

Thomas Spratt, Committee Member & Major Field Represnt
James Broach, Committee Member & Major Field Represnt
Ralph Keil, Committee Member & Major Field Represnt
Lisa Shantz, Committee Member & Related Areas Repres
George Moldovan, Chair & Major Field Represnt
Ralph Keil, Program Head/Chair

Author:

Sokirniy, Ivan

Title:

Functional Genomics Approaches to Characterizing Resistance to Targeted Therapies

Graduate Program:

Molecular, Cellular, and Integrative Biosciences

Keywords:

Functional Genomics
Genomics
BCR-ABL
CML
Leukemia
Deep Mutational Scanning
CRISPR
Base Editing
Targeted Therapies
Asciminib
Imatinib
Epistasis
Resistance
DMS
ABL
ABL1
FRET
Cancer

File:

Download IvanDissert250407.pdf

Committee Members:

Melissa Rolls, Program Head/Chair
Mark Hedglin, Major Field Member
Justin Pritchard, Chair & Dissertation Advisor
Sinisa Dovat, Outside Unit Member
C Okafor, Outside Field Member

Author:

Pale, Lindsey

Title:

Identifying Novel Factors Involved in Cancer Therapy Sensitivity and Resistance using Genome-Wide CRISPR Screens

Graduate Program:

Biomedical Sciences

Keywords:

CRISPR
DNA Repair
DNA Damage
Cancer
BRCA
Cisplatin
PARP Inhibitor
PRIMPOL

File:

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Committee Members:

James Broach, Major Field Member
Zhonghua Gao, Major Field Member
George Moldovan, Chair & Dissertation Advisor
Lisa Shantz, Program Head/Chair
Lisa Shantz, Outside Unit & Field Member

Author:

Howells, Alessandro

Title:

Genetic Engineering of Human Pluripotent Stem Cells: Approaches and Applications in Regenerative Medicine

Graduate Program:

Biomedical Engineering

Keywords:

Human pluripotent stem cells
Genetic engineering
Focused ultrasound
CRISPR
Heat shock promoters
Acoustic reporter genes
modRNA
Immune rejection

File:

No files available due to restrictions.

Committee Members:

Xiaojun Lian, Chair & Dissertation Advisor
Shaun Mahony, Outside Unit & Field Member
Daniel Hayes, Major Field Member
Daniel Hayes, Program Head/Chair
Yuguo Lei, Major Field Member