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Author:

Messina, Kyle

Title:

Influence of biological small molecules on the twister ribozyme and development of methodologies to study and discover small ribozymes

Graduate Program:

Chemistry

Keywords:

RNA
Twister Ribozyme
Kinetics
Small Molecule
Cryo-EM
Bioinformatics

File:

Download Messina_KJ_2019_Dissertation.pdf

Committee Members:

Philip C Bevilacqua, Dissertation Advisor/Co-Advisor
Philip C Bevilacqua, Committee Chair/Co-Chair
Carsten Krebs, Committee Member
David D Boehr, Committee Member
Craig Eugene Cameron, Outside Member
Philip C Bevilacqua, Program Head/Chair

Author:

Hu, Kai

Title:

Bioinformatics discovery of chemical diversity in enzyme superfamilies

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

Ribonucleotide Reductase (RNR)
Bioinformatics
Radical chemistry
Class Ie RNR
Deep Mutational Scanning (DMS) strategy

File:

Download Kai_Hu_dissertation_for_submission.pdf

Committee Members:

Benjamin D Allen, Dissertation Advisor/Co-Advisor
Joseph M Bollinger, Jr., Committee Chair/Co-Chair
Amie Kathleen Boal, Outside Member
Ross Cameron Hardison, Committee Member
Melissa Rolls, Program Head/Chair

Author:

Wafula, Eric

Title:

Computational methods for comparative genomics of non-model species: a case study in the parasitic plant family Orobanchaceae

Graduate Program:

Biology

Keywords:

Computational biology
Evolutionary biology
Bioinformatics
Comparative genomics
Next-generation sequencing
de novo assembly
Genome annotation
Gene expression
Whole genome duplication
Gene duplication
Phylogenomics
Ancestral reconstruction
Transcriptomics
Orthogroups
Gene family evolution
Parasitic plants
Orobanchaceae
Striga

File:

Download Eric_wafula_dissertation_final_submission.pdf

Committee Members:

Claude Walker Depamphilis, Dissertation Advisor/Co-Advisor
James Harold Marden, Committee Chair/Co-Chair
Istvan Albert, Outside Member
Naomi S Altman, Outside Member
Stephen Wade Schaeffer, Program Head/Chair