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Author:

Nelms, Brian Lewis

Title:

SUPPRESSION OF egl-13 SOX DOMAIN MUTANTS REVEALS A NOVEL FUNCTION FOR SOME MEIOTIC GENES

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

C. elegans
egl-13
him-8
uterine
development

File:

Download PhD_eTD_BLN_August_2006.pdf

Committee Members:

Wendy Hanna Rose, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Pamela J Mitchell, Committee Member
David Scott Gilmour, Committee Member
Richard W Ordway, Committee Member

Author:

Zou, Beiyan

Title:

A ROLE FOR MAP1 IN SYNAPTIC FUNCTION REVEALED THROUGH INTERACTIONS WITH PRESYNAPTIC CALCIUM CHANNELS IN DROSOPHILA

Graduate Program:

Genetics

Keywords:

synaptic transmission
MAP1
presynaptic calcium channel
cacophony
futsch
Drosophila

File:

Download Ph.D_dissertation_from_Beiyan_Zou.pdf

Committee Members:

Douglas Cavener, Committee Chair/Co-Chair
Gong Chen, Committee Member
Kyung An Han, Committee Member
Zhi Chun Lai, Committee Member
Richard W Ordway, Committee Member

Author:

Walsh, Elizabeth Rose

Title:

Eosinophil Functions in the Development of Allergic Asthma

Graduate Program:

Pathobiology

Keywords:

allergic
asthma
eosinophil
T cell
Th2

File:

Download Walsh_ER_Doctoral_Thesis_Final_Version.pdf

Committee Members:

Avery August, Dissertation Advisor/Co-Advisor
Avery August, Committee Member
Margherita Teresa Anna Cantorna, Committee Member
Zhi Chun Lai, Committee Member
Andrea Marie Mastro, Committee Member
Pamela Hankey, Committee Chair/Co-Chair

Author:

Ramos, Edward

Title:

UNRAVELING THE FUNCTIONAL MOTIFS OF THE YAN ENHANCER IN DROSOPHILA MELANOGASTER

Graduate Program:

Genetics

Keywords:

Drosphila
Yan
Module
Enhancer
Gene Regulation

File:

Download ERThesis040903.pdf

Committee Members:

Zhi Chun Lai, Committee Chair/Co-Chair
Andrew G Clark, Committee Member
Stephen Wade Schaeffer, Committee Member
David Scott Gilmour, Committee Member

Author:

Lee, Hyun-Gwan

Title:

ROLES OF THE OCTOPAMINE RECEPTOR OAMB IN ASSOCIATIVE LEARNING, MEMORY, AND REPRODUCTION IN DROSOPHILA MELANOGASTER

Graduate Program:

Genetics

Keywords:

octpamine receptor
OAMB
Conditioned courtship
Ovulation
CaMKII

File:

Download Hyun-thesis.pdf

Committee Members:

Kyung An Han, Committee Member
Richard W Ordway, Committee Member
Zhi Chun Lai, Committee Chair/Co-Chair
Graham Hugh Thomas, Committee Member
David Scott Gilmour, Committee Member

Author:

Sun, Hongliu

Title:

Modulation of C. elegans transcription factor activity by HIM-8 and the related zinc finger ZIM proteins

Graduate Program:

Genetics

Keywords:

HIM-8 suppression
zinc finger ZIM proteins
chromatin modification

File:

Download Thesis_0713.pdf

Committee Members:

Zhi Chun Lai, Committee Chair/Co-Chair
Wendy Hanna Rose, Committee Member
Pamela Hankey Giblin, Committee Member
Pamela J Mitchell, Committee Member
Diana Lynn Cox Foster, Committee Member

Author:

Chen, Jianping

Title:

MOLECULAR, BIOCHEMICAL, AND FUNCTIONAL CHARACTERIZATION OF RICE MAP KINASE SUBSTRATES

Graduate Program:

Integrative Biosciences

Keywords:

CDPK
ethylene signaling
phosphorylation screening
OsMPK5
stresses

File:

Download Jianping_Dissertation_2009.pdf

Committee Members:

Yinong Yang, Dissertation Advisor/Co-Advisor
Yinong Yang, Committee Chair/Co-Chair
Richard Cyr, Committee Member
Zhi Chun Lai, Committee Member
Timothy W Mcnellis, Committee Member

Author:

Yao, Jun

Title:

FUNCTIONAL ROLE OF CYTOSKELETON PROTEIN ACTIN IN SYNAPSE MATURATION AND PLASTICITY

Graduate Program:

Biology

Keywords:

actin
activity
synaptic platicity
presynaptic
silent synapse
hippocampus

File:

Download Yao_Final_Thesis.pdf

Committee Members:

Gong Chen, Committee Chair/Co-Chair
Richard W Ordway, Committee Member
Zhi Chun Lai, Committee Member
Si Qiong Liu, Committee Member
Pamela J Mitchell, Committee Member

Author:

Wei, Jianwen

Title:

PERK IS ESSENTIAL FOR NEONATAL SKELETAL DEVELOPMENT TO REGULATE OSTEOBLAST BIOLOGY

Graduate Program:

Genetics

Keywords:

PERK
osteoblast
Runx2
procollagen
proliferation
endoplasmic reticulum

File:

Download Jianwen_Thesis.pdf

Committee Members:

Zhi Chun Lai, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Richard W Ordway, Committee Member
Carol V Gay, Committee Member
Pamela J Mitchell, Committee Member

Author:

Zou, Jizhong

Title:

Cis-elements for Notch-dependent expression and autoregulation of Drosophila AP-2 in developing leg and antenna

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

comparative genomics
Drosophila
enhancer
Notch signaling
leg development
transcription factor AP-2

File:

Download ZouThesisFinalHQ.pdf

Committee Members:

David Scott Gilmour, Committee Member
Ross Cameron Hardison, Committee Member
Zhi Chun Lai, Committee Member
Pamela J Mitchell, Committee Chair/Co-Chair
Kyung An Han, Committee Member

Author:

Estes, Kathleen Anne

Title:

ANALYSIS OF C. ELEGANS VULVAL MORPHOGENESIS REVEALS NOVEL MECHANISMS FOR INITIATION AND MAINTENANCE OF BIOLOGICAL TUBES

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

tubulogenesis
lumen
anchor cell
c. elegans
development
vulva
egl-26
NlpC/p60

File:

Download ThesisMaster_FINAL.pdf

Committee Members:

Wendy Hanna Rose, Dissertation Advisor/Co-Advisor
Wendy Hanna Rose, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Lorraine C Santy, Committee Member
Douglas Cavener, Committee Member
Zhi Chun Lai, Committee Member

Author:

Markell, Lauren Mordasky

Title:

PHARMACOLOGICAL INHIBITION OF THE TGF-BETA TYPE I RECEPTOR REVEALS A DUAL ROLE OF TGF-BETA IN CARCINOGENESIS

Graduate Program:

Integrative Biosciences

Keywords:

skin
skin carcinogenesis
TGF-beta
chemically-induced carcinogenesis

File:

Download Lauren_Mordasky_Markell_Dissertation.pdf

Committee Members:

Adam Bleier Glick, Dissertation Advisor/Co-Advisor
Adam Bleier Glick, Committee Chair/Co-Chair
John Patrick Vanden Heuvel, Committee Member
Gary H Perdew, Committee Member
Zhi Chun Lai, Committee Member
Jeffrey Maurice Peters, Committee Member

Author:

Hao, Li

Title:

Evolution of Natural Killer Cell Receptor Genes

Graduate Program:

Biology

Keywords:

birth-and-death
Natural killer receptors
Evolution
duplication

File:

Download thesis_2006-3-21.pdf

Committee Members:

Masatoshi Nei, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Wojciech Makalowski, Committee Member
Robert Paulson, Committee Member

Author:

Ho, Li-Lun

Title:

MOB as Tumor Suppressor is Activated at the Plasma Membrane to Control Tissue Growth and Organ size in Drosophila

Graduate Program:

Integrative Biosciences

Keywords:

Mats
tumor suppressor
Hippo signaling
organ size control

File:

Download Thesis__Li-Lun_Ho.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Avery August, Committee Member
Douglas Cavener, Committee Member
Richard John Frisque, Committee Member
Aimin Liu, Committee Member
Robert Paulson, Committee Member
Peter John Hudson, Committee Member

Author:

Quan, Li

Title:

FUNCTIONAL AND EVOLUTIONARY ANALYSES OF KINESIN AND MEIOTIC GENES IN PLANTS

Graduate Program:

Biology

Keywords:

kinesin
meiosis
spindle
gene duplication
homologous recombination
functional divergence

File:

Download Dissertation-Li_Quan.pdf

Committee Members:

Hong Ma, Committee Chair/Co-Chair
Teh Hui Kao, Committee Member
Richard Cyr, Committee Member
Zhi Chun Lai, Committee Member

Author:

Huang, Li

Title:

MOLECULAR CLONING OF A C. elegans LONGEVITY GENE pnc-1 AND INVESTIGATION OF ITS NOVEL FUNCTION IN DEVELOPMENT

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

nicotiamidase
gonad development
egg-laying defect
EGF signaling
uv1 cells
NAD

File:

Download LiHuang_Thesis_2008.pdf

Committee Members:

Wendy Hanna Rose, Committee Chair/Co-Chair
Diana Lynn Cox Foster, Committee Member
Emine Koc, Committee Member
Zhi Chun Lai, Committee Member
Pamela J Mitchell, Committee Member

Author:

Shi, Lei

Title:

The role of Sf-Stk in stress erythropoiesis

Graduate Program:

Integrative Biosciences

Keywords:

stress erythropoiesis
Sf-Stk
Friend Virus

File:

Download Thesis_Lei_Shi.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
Pamela Hankey, Committee Member
Wendy Hanna Rose, Committee Member
Zhi Chun Lai, Committee Member
Naomi S Altman, Committee Member

Author:

Fetchko, Michael John

Title:

MOLECULAR GENETIC ANALYSIS OF DROSOPHILA EYE DEVELOPMENT: INVESTIGATION OF A LEUCINE-RICH REPEAT PROTEIN'S ROLE IN CELL-CELL COMMUNICATION

Graduate Program:

Biochemistry and Molecular Biology

Keywords:

DROSOPHILA
EYE DEVELOPMENT
DEVELOPMENT
TISSUE PATTERNING
NOTCH PATHWAY
CELL-CELL SIGNALING

File:

Download FinalThesisMJF180.pdf

Committee Members:

Zhi Chun Lai, Committee Chair/Co-Chair
Esther Siegfried, Committee Member
Richard W Ordway, Committee Member
Susan Abmayr, Committee Member
Olanrewaju A Sodeinde, Committee Member

Author:

Rohrbaugh, Margaret C.

Title:

MOLECULAR AND GENETIC STUDIES OF CELLULAR REGULATORY MECHANISMS USING DROSOPHILA MELANOGASTER AS A MODEL SYSTEM

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Drosophila
Yan
Cell Cycle
Notch Signaling
Development
Gp150

File:

Download Rohrbaugh.pdf

Committee Members:

Zhi Chun Lai, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
Richard W Ordway, Committee Member
Benjamin Franklin Pugh, Committee Member
Esther Siegfried, Committee Member

Author:

Piontkivska, Olena

Title:

Evolution of multigene families: histone and major histocompatibility complex genes

Graduate Program:

Genetics

Keywords:

histone
H3
H4
multigene family
concerted evolution
birth-and-death evolution
purifying selection
MHC
class I
divergence time
primates

File:

Download thesis.pdf

Committee Members:

Masatoshi Nei, Committee Chair/Co-Chair
Claude Walker Depamphilis, Committee Member
David Michael Geiser, Committee Member
Zhi Chun Lai, Committee Member
Richard W Ordway, Committee Member

Author:

Kalantari, Parisa

Title:

POSITIVE AND NEGATIVE REGULATION OF HIV REPLICATION IN MACROPHAGES: ROLE OF RON RECEPTOR TYROSINE KINASE

Graduate Program:

Pathobiology

Keywords:

HIV
RON receptor tyrosine kinase
Tat
proteosome dependent degradation

File:

Download Thesis_submission.pdf

Committee Members:

Andrew Thomas Henderson, Committee Chair/Co-Chair
Pamela Hankey Giblin, Committee Member
Avery August, Committee Member
Richard John Frisque, Committee Member
Zhi Chun Lai, Committee Member

Author:

Li, Pingxin

Title:

ANALYSIS OF PEPTIDYLARGININE DEIMINASE 4 AND HISTONE CITRULLINATION IN TRANSCRIPTIONAL REGULATION AND INNATE IMMUNITY

Graduate Program:

Genetics

Keywords:

Peptidylarginine Deiminase 4
Histone Citrullination
p53
p21
Histone Deacetylase 2
Neutrophil Extracellular Traps

File:

Download Pingxin_Li_Dissertation.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Yanming Wang, Committee Member
David Scott Gilmour, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Joseph C. Reese, Committee Member
Robert Paulson, Committee Member

Author:

Qi, Qian

Title:

ROLE OF ITK IN THE DEVELOPMENT OF INNATE T CELLS

Graduate Program:

Immunology and Infectious Diseases

Keywords:

gammadelta T cell
Itk structure
innate T cell
Itk
BiFC assay

File:

Download Graduation_Thesis_Qian_Qi.pdf

Committee Members:

Avery August, Dissertation Advisor/Co-Advisor
Avery August, Committee Chair/Co-Chair
Biao He, Committee Member
Margherita Teresa Anna Cantorna, Committee Member
Pamela Hankey Giblin, Committee Member
Robert Paulson, Committee Member
Zhi Chun Lai, Committee Member

Author:

Acharjee, Shaona

Title:

A GENETIC SCREEN FOR SECOND CHROMOSOME MODIFIERS OF A TEMPERATURE-SENSITIVE PRESYNAPTIC CALCIUM CHANNEL MUTANT OF DROSOPHILA

Graduate Program:

Biology

Keywords:

Drosophila
neurotransmission
cac
temperature- sensitive
paralysis
calcium channel

File:

Download thesis-shaona1.pdf

Committee Members:

Richard W Ordway, Committee Chair/Co-Chair
Kyuang Han, Committee Member
Zhi Chun Lai, Committee Member
Wendy Hanna Rose, Committee Member

Author:

Gupta, Sounak

Title:

PERK (EIF2AK3) REGULATES PROINSULIN TRAFFICKING AND QUALITY CONTROL IN THE SECRETORY PATHWAY

Graduate Program:

Molecular Medicine

Keywords:

DIABETES
TRAFFICKING
PERK
INSULINOMA
ENDOPLASMIC RETICULUM
PROINSULIN

File:

Download SounakGupta-Thesis-Aug2010.pdf

Committee Members:

Douglas Cavener, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Member
Robert Paulson, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Wendy Hanna Rose, Committee Member
Kouacou Konan, Committee Member

Author:

He, Shihan

Title:

MECHANISM OF GP55 MEDIATED SF-STK ACTIVATION

Graduate Program:

Pathobiology

Keywords:

erythroid progenitor cell
short form Stk receptor tyrosine kinase
murine erythroleukemia
Friend virus
protein inteaction
cell signaling

File:

Download Shihan_thesis.pdf

Committee Members:

Pamela Hankey Giblin, Dissertation Advisor/Co-Advisor
Pamela Hankey Giblin, Committee Chair/Co-Chair
Avery August, Committee Member
Biao He, Committee Member
Robert Paulson, Committee Member
Zhi Chun Lai, Committee Member

Author:

Vrablik, Tracy Lynn

Title:

NICOTINAMIDASE MODULATION OF NICOTINAMIDE LEVELS AND NAD+ SYNTHESIS SEPARATELY AFFECT DEVELOPMENT AND PHYSIOLOGY OF MULTIPLE ORGAN SYSTEMS IN C. ELEGANS

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

NAD+ metabolism
niacin
development

File:

Download VrablikThesis022811.pdf

Committee Members:

Wendy Hanna Rose, Dissertation Advisor/Co-Advisor
Wendy Hanna Rose, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Zhi Chun Lai, Committee Member
Troy Ott, Committee Member
Squire J Booker, Committee Member

Author:

Shimizu, Takeshi

Title:

The Drosophila Model of Cancer: Characterization of a Conserved Tumour Suppressor and Its Role in the Control of Cell Proliferation and Apoptosis

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

cancer biology
tumor suppressor
wts
lats
hpo
mats
Drosophila

File:

Download VersionR04.pdf

Committee Members:

Zhi Chun Lai, Committee Chair/Co-Chair
Carol V Gay, Committee Member
Richard W Ordway, Committee Member
Robert Paulson, Committee Member
Wendy Hanna Rose, Committee Member

Author:

Yu, Wenhua

Title:

IN VIVO FUNCTION AND INTERACTION OF SNARES, NSF AND SNAP DURING PRESYNAPTIC VESICLE TRAFFICKING IN DROSOPHILA

Graduate Program:

Genetics

Keywords:

synaptic function
NSF
SNAP
SNAREs
live imaging
FRET
Drosophila

File:

Download Wenhua_Yu_Dissertation.pdf

Committee Members:

Richard W Ordway, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Richard W Ordway, Committee Member
Wendy Hanna Rose, Committee Member
Aimin Liu, Committee Member
Douglas Cavener, Committee Member

Author:

Ye, Xin

Title:

GROWTH CONTROL BY HIPPO AND AKT SIGNALING PATHWAYS IN DROSOPHILA MELANOGASTER

Graduate Program:

Genetics

Keywords:

growth control
Hippo
Akt
Drosophila

File:

Download final_thesis_07272010.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Member
Robert Paulson, Committee Chair/Co-Chair
Richard W Ordway, Committee Member
Wendy Hanna Rose, Committee Member
Yanming Wang, Committee Member

Author:

Xu, Xu

Title:

The GCN2 eIF2alpha kinase regulates lipid and glucose homeostasis

Graduate Program:

Cell and Developmental Biology

Keywords:

GCN2
FSP27
Triglyceride Storage
Insig2a
C/EBPbeta
Gluconeogenesis

File:

Download 11282011_Xu_Xu_Ph.D_thesis_final_eTD.pdf

Committee Members:

Douglas Cavener, Dissertation Advisor/Co-Advisor
Gong Chen, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Zhi Chun Lai, Committee Member
Robert Paulson, Committee Member

Author:

Zhou, Xiaofan

Title:

UNDERSTANDING EVOLUTIONARY HISTORY USING MOLECULAR PHYLOGENETICS: FROM GENES TO GENOMES

Graduate Program:

Cell and Developmental Biology

Keywords:

genome duplication
gene duplication
histone demethylase
epigenetics
evolution
tree of life
single-copy gene

File:

Download ZhouX_PhD_Dissertation.pdf

Committee Members:

Hong Ma, Dissertation Advisor/Co-Advisor
Hong Ma, Committee Chair/Co-Chair
Claude Walker Depamphilis, Committee Member
Zhi Chun Lai, Committee Member
David Michael Geiser, Committee Member

Author:

Wei, Xiaomu

Title:

Control of Cell Proliferation and Apoptosis by Mob as Tumor Suppressor Protein

Graduate Program:

Genetics

Keywords:

hippo
growth inhibition and tumor suppression
Drosophila
mats
warts

File:

Download Xiaomu_Wei.pdf

Committee Members:

Richard W Ordway, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Douglas Cavener, Committee Member
Gong Chen, Committee Member
Wendy Hanna Rose, Committee Member

Author:

Wu, Xianting

Title:

The role of barren inflorescence genes, barren inflorescence2 (bif2), barren stalk1 (ba1)and suppressor of sessile spikelet1 (sos1), in maize inflorescence development

Graduate Program:

Biology

Keywords:

barren inflorescence
maize
inflorescence development

File:

Download Xianting_Wu_Ph.D_thesis.pdf

Committee Members:

Paula Mc Steen, Committee Chair/Co-Chair
Hong Ma, Committee Member
Zhi Chun Lai, Committee Member
Kathleen Marie Brown, Committee Member

Author:

Lin, Zhenguo

Title:

THE ORIGINS AND EVOLUTION OF HIGHLY CONSERVED GENE FAMILIES CONCERNED WITH BASIC CELLULAR AND DEVELOPMENT PROCESSES

Graduate Program:

Biology

Keywords:

evolution
origin
DNA repair
development
RAD51
recA
MutS
MutL
Hox

File:

Download LinZ_PhD_Thesis_2008.pdf

Committee Members:

Hong Ma, Committee Chair/Co-Chair
Masatoshi Nei, Committee Chair/Co-Chair
Teh Hui Kao, Committee Member
Zhi Chun Lai, Committee Member

Author:

Iyer, Janani

Title:

Genetic Analysis of Synaptic Transmission

Graduate Program:

Genetics

Keywords:

Genetic Analysis
Synaptic Transmission
Drosophila melanogaster
Neurotransmission

File:

Download Janani_Iyer_Dissertation.pdfDownload Proquest_Agreement.pdfDownload doctoral_approval_page001.pdfDownload eTD_approval_form002.pdfDownload Survey_of_earned_doctorates_005.pdf

Committee Members:

Fumiko Kawasaki, Dissertation Advisor/Co-Advisor
Richard W Ordway, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Wendy Hanna Rose, Committee Member

Author:

Sun, Chicheng

Title:

The function of neuroligin-2 in neuronal development and neuropsychiatric disorders

Graduate Program:

Cell and Developmental Biology

Keywords:

Neuroligin
Synapse
GABA
Schizophrenia
KCC2

File:

Download Chicheng_Sun_Thesis.pdf

Committee Members:

Gong Chen, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Richard W Ordway, Committee Member
Rick Owen Gilmore, Committee Member

Author:

Wang, Xin

Title:

The Juxtamembrane Domain: a Central Guardian of the Ron Receptor Tyrosine Kinase Activity

Graduate Program:

Cell and Developmental Biology

Keywords:

Juxtamembrane domain
Ron Receptor Tyrosine Kinase
Autoinhibition

File:

Download final_Dissertation_of_Xin_Wang.pdf

Committee Members:

Pamela Hankey Giblin, Dissertation Advisor/Co-Advisor
Pamela Hankey Giblin, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Avery August, Special Member
B Tracy Nixon, Committee Member
Kumble Sandeep Prabhu, Committee Member

Author:

Hu, Jing

Title:

Roles of hepatoma-derived growth factor related protein 2 and ovary kidney and liver protein 38 in cell growth, apoptosis and DNA damage response

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

HDGF2
OKL38
Cell growth
Apoptosis
DNA damage response

File:

Download JingHu_Thesis_2013.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Yanming Wang, Committee Chair/Co-Chair
David Scott Gilmour, Committee Member
Ying Gu, Committee Member
Zhi Chun Lai, Committee Member
Na Xiong, Committee Member

Author:

Xu, Pei

Title:

study of a mumps virus from a outbreak in Iowa in 2006

Graduate Program:

Cell and Developmental Biology

Keywords:

mumps virus vaccine rhesus macaque V SH attenuation

File:

Download pei_xu_thesis-final__7-19-2013.pdf

Committee Members:

Biao He, Dissertation Advisor/Co-Advisor
Anthony Paul Schmitt, Dissertation Advisor/Co-Advisor
Na Xiong, Committee Member
Zhi Chun Lai, Committee Member
Pamela Hankey Giblin, Committee Member

Author:

Ravindran, Anand

Title:

The Role Of TGFβ Signaling In Ultraviolet Radiation (UVB)-Induced Cutaneous Inflammation And Carcinogenesis

Graduate Program:

Pathobiology

Keywords:

Skin Cancer
Ultraviolet Radiation
Transforming Growth Factor-Beta
Inflammation
Dendritic cell
T lymphocyte Activation

File:

Download Anand_Ravindran_Pathobiology_PhD_Dissertation.pdf

Committee Members:

Adam Bleier Glick, Dissertation Advisor/Co-Advisor
Adam Bleier Glick, Committee Chair/Co-Chair
Gary H Perdew, Committee Member
Pamela Hankey Giblin, Committee Member
Sagarika Kanjilal, Committee Member
Zhi Chun Lai, Special Member

Author:

Wang, Rong

Title:

PERK eIF2alpha kinase regulates cell proliferation, insulin synthesis and secretion in pancreatic beta cells

Graduate Program:

Genetics

Keywords:

PERK eIF2alpha kinase
Ca2+ dynamics
insulin secretion
insulin biosynthesis
diabetes
ER stress
beta cell proliferation

File:

Download Rong_Wang_Thesis_Dissertation.pdf

Committee Members:

Douglas Cavener, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Richard W Ordway, Committee Member
Gong Chen, Committee Member
Melissa Rolls, Committee Member

Author:

Yu, Tian

Title:

Integrative analyses of hippo pathway Mutations in human cancer genome

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

mutation
cancer genome
Hippo Pathway
signal transduction
tumor
mutation correlation

File:

Download Tian_Yus_dissertation_Dec_final.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Francisco Javier Diaz, Committee Member
Graham Hugh Thomas, Committee Member
Robert Paulson, Special Member

Author:

Deng, Yaoting

Title:

Regulation of Hippo Signaling for Growth Control

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Hippo pathway
Hippo
transphosphorylation
dimerization
Merlin
Expanded
Kibra
FFA
β-cells
Yap
F-actin
apoptosis

File:

Download Dissertation_Yaoting_Deng.pdf

Committee Members:

Zhi Chun Lai, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Pamela Hankey Giblin, Committee Member
Richard W Ordway, Committee Member
Wendy Hanna Rose, Committee Member
Yanming Wang, Committee Member

Author:

Zhao, Na

Title:

Investigation of the molecular genetics of Drosophila synapse assembly

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

synapse development
GluRIIA localization
subsynaptic reticulum
Akt
heparan sulfate proteolycan
autophagy
Acinus
spectrin

File:

Download Dissertation_Thesis-_Na_Zhao_final_submission.pdf

Committee Members:

Scott Brian Selleck, Dissertation Advisor/Co-Advisor
Scott Brian Selleck, Committee Chair/Co-Chair
Bernhard Luscher, Committee Member
Richard W Ordway, Committee Member
Zhi Chun Lai, Committee Member

Author:

Xiang, Jie

Title:

REGULATION OF STRESS ERYTHROPOIESIS: INTERACTION BETWEEN MICROENVIRONMENT AND STRESS ERYTHROID PROGENITORS

Graduate Program:

Integrative Biosciences

Keywords:

Stress erythropoiesis
Stem cell
Epo
progenitors
Anemia

File:

Download Jie_Xiang-Phd_Thesis-_final_updated.pdf

Committee Members:

Robert Paulson, Dissertation Advisor/Co-Advisor
Robert Paulson, Committee Chair/Co-Chair
Ross Cameron Hardison, Committee Member
Zhi Chun Lai, Committee Member
Kumble Sandeep Prabhu, Committee Member
Yanming Wang, Committee Member
Naomi S Altman, Committee Member

Author:

Liu, Jinling

Title:

Genetic analyses of the cilia-dependent hedgehog signal transduction in the mouse

Graduate Program:

Biology

Keywords:

hedgehog
spinal cord patterning
Gli
Sufu
cilia

File:

Download Jinling_Liu_Dissertation_Dec_2_Final.pdf

Committee Members:

Aimin Liu, Dissertation Advisor/Co-Advisor
Zhi Chun Lai, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Robert Paulson, Committee Member

Author:

Tao, Juan

Title:

Microtubule destabilizers control axon and dendrite disassembly after injury and during pruning

Graduate Program:

Biochemistry and Molecular Biology

Keywords:

Drosophila axon dendrite degeneration

File:

Download After_thesis_defense_23_Juan_Tao_Thesis.pdf

Committee Members:

Melissa Rolls, Dissertation Advisor/Co-Advisor
Melissa Rolls, Committee Chair/Co-Chair
Lorraine C Santy, Committee Member
Zhi Chun Lai, Committee Member
Richard W Ordway, Special Member

Author:

Chen, Li

Title:

Investigation of the molecular basis underlying a multi-step model of axon injury responses

Graduate Program:

Cell and Developmental Biology

Keywords:

axon regeneration
neuroprotection
microtubules
gamma-tubulin
Nmnat
DLK
JNK
fos
caspases
mitochondria

File:

Download ChenDissertationJuly15.pdf

Committee Members:

Melissa Rolls, Dissertation Advisor/Co-Advisor
William O Hancock, Committee Member
Richard W Ordway, Committee Member
Douglas Cavener, Committee Member
Zhi Chun Lai, Committee Member

Author:

Chen, Xiangyun

Title:

Novel Self-assemble nanoparticles to inhibit cancer growth -effects on ER stress, autophagy, and multidrug resistance by a small molecule

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

Nanomedicine
Multi-drug resistance
cancer

File:

Download XAC-Thesis-20151209-2.pdf

Committee Members:

Yanming Wang, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Chair/Co-Chair
Zhi Chun Lai, Committee Member
Lu Bai, Committee Member
Gavin Peter Robertson, Special Member

Author:

Sun, Tianyanxin

Title:

The Roles of Hippo Signaling Pathway in Mouse Ovarian Function

Graduate Program:

Physiology

Keywords:

Hippo Signaling
Follicular Development
Ovulation
YAP1
LATS1
Mouse

File:

Download Dissertation_Tian_Sun_20160413.pdf

Committee Members:

Francisco Javier Diaz, Dissertation Advisor/Co-Advisor
Alan Leslie Johnson, Committee Member
Kevin John Harvatine, Committee Member
Ramesh Ramachandran, Committee Member
Zhi Chun Lai, Committee Member