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Author:

Gaskin, Byron Jerrod

Title:

Coupled biophysical simulations of cell-cell interaction and drug delivery microrobots

Graduate Program:

Bioengineering

Keywords:

computational mechanics
personalized medicine
computational fluid dynamics
computational structural mechanics
biochemistry
fluid dynamics
solid mechanics
continuum mechanics
blood flow
blood cells
drug delivery
drug targeting
microrobotics
flowing bodies
hyperelasticity
rigid body motion

File:

Download BJG_PhD_Final.pdf

Committee Members:

Robert Francis Kunz, Dissertation Advisor/Co-Advisor
Robert Francis Kunz, Committee Chair/Co-Chair
Cheng Dong, Committee Member
William O Hancock, Committee Member
Robert Lee Campbell, Outside Member
Sean Michael Mcintyre, Special Member

Author:

Unsal, Hayreddin Said

Title:

Measuring Resting State Functional Connectivity in Awake Mouse’s Brain Using fMRI

Graduate Program:

Bioengineering

Keywords:

functional connectivity
resting state fMRI
brain
mouse
awake animal

File:

Download HayreddinSaidUnsal_MastersThesis_FinalSubmission_revised.pdf

Committee Members:

Nanyin Zhang, Thesis Advisor/Co-Advisor
Jian Yang, Committee Member
William O Hancock, Committee Member

Author:

Saravanan, Pratima

Title:

THE EFFECT OF GEOMETRY, HEMODYNAMICS, AND TISSUE FACTOR ON CLOT FORMATION IN ANEURYSM MODELS

Graduate Program:

Bioengineering

Keywords:

aneurysm
hemodynamics
tissue factor
thrombus
wall shear stress
poly (1
8 - octane diol citrate)

File:

Download Pratima_Saravanan_Thesis.pdf

Committee Members:

Keefe B Manning, Thesis Advisor/Co-Advisor
Jian Yang, Committee Member
William O Hancock, Committee Member

Author:

Turrigiano, Antonino Vincent

Title:

A QUANTIFIED METHOD OF DISTINGUISHING PATTERNS IN SESSILE DROPLETS OF WHOLE HUMAN BLOOD

Graduate Program:

Bioengineering

Keywords:

Sessile drop
Blood
Desiccation
Quantitative analysis
Medical
Diagnostic

File:

Download Final_Thesis.AVT.pdf

Committee Members:

Tak Sing Wong, Thesis Advisor/Co-Advisor
William O Hancock, Committee Member
Pak Kin Wong, Committee Member

Author:

Son, Seoyoung

Title:

THE ROLE OF THE MEMBRANE IN INTEGRIN-MEDIATED ADHESION OF CELLS TO SURFACES

Graduate Program:

Bioengineering

Keywords:

Integrin
Membrane mechanical Properties
Time-correlated single photon microscopy
Cell adhesion
Fluorescence correlation spectroscopy
Optical trap

File:

Download Dissertation_Final.pdf

Committee Members:

Peter J Butler, Dissertation Advisor/Co-Advisor
Peter J Butler, Committee Chair/Co-Chair
William O Hancock, Committee Member
Justin Lee Brown, Committee Member
Tae-Hee Lee, Outside Member
Esther Winter Gomez, Committee Member

Author:

Roby, Alison C

Title:

The functional connectivity changes in the rat brain following acute and chronic nicotine administration

Graduate Program:

Bioengineering

Keywords:

functional connectivity
nicotine addiction
individual difference
acute administration

File:

Download grad_template_final2.pdf

Committee Members:

Nanyin Zhang, Thesis Advisor/Co-Advisor
William O Hancock, Committee Member
David John Vandenbergh, Committee Member

Author:

Li, Harvey S

Title:

THE EFFECTS OF CELL MORPHOLOGY ON NANOPARTICLE UPTAKE AND UPTAKE AT THE LEADING EDGE IN MC3T3 CELLS

Graduate Program:

Bioengineering

Keywords:

cell
cell morphology
nanoparticles
endocytosis
immunostaining
live-cell imaging
MC3T3 cells
microcontact printing
y-27632

File:

Download MASTERS_Thesis_FINAL.pdf

Committee Members:

Justin Lee Brown, Thesis Advisor/Co-Advisor
William O Hancock, Committee Member
Xiaojun Lian, Committee Member

Author:

Steltz, Austin E

Title:

THE EFFECT OF MICROFIBER MORPHOLOHY AND CELL DENSITY ON THE LOCALIZATION OF YAP PROTEIN IN MESENCHYMAL STEM CELLS

Graduate Program:

Bioengineering

Keywords:

mesenchymal stem cell
msc
mouse
YAP
Yes Associated Protein
Transduce
Mechanotransduction
biology
biomedical engineering
microfibers
fibers
flat
electrospinning
confluence
cell density

File:

Download Austin_Steltz_Thesis_Graduate_School.pdf

Committee Members:

Justin Lee Brown, Thesis Advisor/Co-Advisor
William O Hancock, Committee Member
Yong Wang, Committee Member

Author:

Blaszczyk, Anthony J

Title:

IN VITRO STUDIES OF CLASS B METHYLASES, AN ELUSIVE CLASS OF COBALAMIN-DEPENDENT RADICAL SAM ENZYMES

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

enzyme
cobalamin
s-adenosylmethionine
radical sam
protein purification
biochemistry
mechanistic enzymology
methylation
Class B methylase
TsrM
Fom3
PhpK

File:

Download Thesis_Blaszczyk_Final_II.docx.pdf

Committee Members:

Squire J Booker, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Chair/Co-Chair
Carsten Krebs, Committee Member
Joseph M Bollinger Jr., Committee Member
William O Hancock, Outside Member
Amie Kathleen Boal, Committee Member

Author:

Schwalm, Erica Lynne

Title:

Investigation of the Radical SAM RNA Methylases RlmN and Cfr

Graduate Program:

Chemistry

Keywords:

radical SAM
RNA
enzymes
methylation

File:

Download Schwalm_Dissertation.pdf

Committee Members:

Squire J Booker, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Chair/Co-Chair
Amie Kathleen Boal, Committee Member
Carsten Krebs, Committee Member
William O Hancock, Outside Member

Author:

Aragon Sanabria, Virginia

Title:

CELL-CELL INTERACTIONS IN THE TUMOR MICROENVIRONMENT: OVERCOMING THE ENDOTHELIAL BARRIER FOR TARGETED DRUG DELIVERY STRATEGIES

Graduate Program:

Biomedical Engineering

Keywords:

Endothelial cells
Gap formation
Tumor Microenvironment
Nanoparticles
Immune-mediated therapy
Metastasis
Cell-cell interactions

File:

Download VAS_-_Final_Thesis.pdf

Committee Members:

Cheng Dong, Dissertation Advisor/Co-Advisor
Cheng Dong, Committee Chair/Co-Chair
Esther Winter Gomez, Committee Member
William O Hancock, Committee Member
Andrea M. Mastro, Outside Member

Author:

Chen, Geng Yuan

Title:

CONTRIBUTION OF KINESIN-MEDIATED MICROTUBULE DYNAMICS TO THE REGULATION OF MITOTIC SPINDLE STABILITY: MOLECULAR MECHANISM OF KINESIN-MICROTUBULE INTERACTION

Graduate Program:

Bioengineering

Keywords:

Kinesin
Microtubule
Microtubule-associated protein
Eg5 inhibitors
Mitosis
Size-scaling problem
Single-molecule
transient kinetics
Tubulin dynamics

File:

Download _20180720__Geng-Yuan_Chen_Dissertation.pdf

Committee Members:

William O Hancock, Dissertation Advisor/Co-Advisor
William O Hancock, Committee Chair/Co-Chair
Peter J Butler, Committee Member
Justin Lee Brown, Committee Member
Melissa Rolls, Outside Member

Author:

Pisupati, Aditya

Title:

Structure-Function Relationships and Biochemical Manipulation of 6-TM Superfamily Ion Channels

Graduate Program:

Neuroscience

Keywords:

ion channels
voltage-gated
structure
function
six-transmembrane
6-TM
Shaker
CNBD
TRPV

File:

Download AP_Thesis_Final.pdf

Committee Members:

Timothy J Jegla, Dissertation Advisor/Co-Advisor
Timothy J Jegla, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Bernhard Luscher, Committee Member
William O Hancock, Outside Member
Santhosh Girirajan, Committee Member

Author:

Yan, Chao

Title:

Gene Regulation By Divergent Gene Pairs and Nucleosome Depleting Factors

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

Nucleosome depleting factors
divergent gene pairs
divergent transcription
transcription
gene regulation

File:

Download 1810_Thesis_Draft_Chao_final.pdf

Committee Members:

Lu Bai, Dissertation Advisor/Co-Advisor
Lu Bai, Committee Chair/Co-Chair
Joseph C. Reese, Committee Member
Benjamin Franklin Pugh, Committee Member
William O Hancock, Outside Member
Shaun A Mahony, Committee Member