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Open Access

Author:: Kline, Christina Leah Banta
Title:: Potential of Prostate Apoptosis Response protein-4 (Par-4) in colon cancer therapy
Graduate Program:: Integrative Biosciences
Keywords:: c-Src
Par-4
prostate apoptosis response protein-4
colon cancer
5-fluorouracil
File:: Download KlineCLPar42011.pdf
Committee Members:: Rosalyn Bryson Irby, Dissertation Advisor/Co-Advisor
Harriet C Isom, Committee Member
Shantu G Amin, Committee Member
Rosalyn Bryson Irby, Committee Chair/Co-Chair
Thomas E Spratt, Committee Member

Open Access

Author:: Shuman, Laurie Ann
Title:: Interaction of Metastatic Breast Cancer Cells with Osteoblasts
Graduate Program:: Immunology and Infectious Diseases
Keywords:: transcription factor
cytokine
metastasis
osteoblast
Breast cancer
File:: Download ShumanThesis2009.pdf
Committee Members:: Andrea Marie Mastro, Dissertation Advisor/Co-Advisor
Andrea Marie Mastro, Committee Chair/Co-Chair
Adam Bleier Glick, Committee Member
Rosalyn Bryson Irby, Committee Member
Robert Paulson, Committee Member
Danny Welch, Committee Member

Open Access

Author:: Shah, Mithun Vinod
Title:: ROLE OF SPHINGOLIPID SIGNALING IN PATHOGENESIS OF LARGE GRANULAR LYMPHOCYTE LEUKEMIA
Graduate Program:: Molecular Medicine
Keywords:: SPHINGOLIPID
LGL LEUKEMIA
FTY720
File:: Download Mithun_Shah.pdf
Committee Members:: Andrew Paul Loughran, Dissertation Advisor/Co-Advisor
"Thomas P Loughran, Jr", Committee Chair/Co-Chair
Rosalyn Bryson Irby, Committee Chair/Co-Chair
Gary Alan Clawson, Committee Member
Edward Joseph Gunther, Committee Member

Open Access

Author:: Fino, Kristin Kelly
Title:: Role of the Cholecystokinin-B Receptor in Proliferation of Pancreatic Cancer
Graduate Program:: Cell and Molecular Biology
Keywords:: pancreatic cancer
gastrin
CCK-BR
G-protein coupled receptor
RNAi
File:: Download THESIS_KFINO_FINAL.pdf
Committee Members:: Jill P Smith, Dissertation Advisor/Co-Advisor
Dr Mark Kester, Committee Chair/Co-Chair
Rosalyn Bryson Irby, Committee Member
Lisa M Shantz, Committee Member
Hong Gang Wang, Special Member

Open Access

Author:: Olson, Thomas Lynn
Title:: Identification of Somatic Mutations in LGL Leukemia through Whole Genome Sequencing and Correlation of STAT3 Y640F Mutation with Treatment Response to Methotrexate.
Graduate Program:: Molecular Medicine
Keywords:: large granular lymphocytes
leukemia
STAT3
TBET
genomics
File:: Download Thomas_L_Olson.pdf
Committee Members:: "Thomas P Loughran, Jr", Dissertation Advisor/Co-Advisor
Rosalyn Bryson Irby, Committee Chair/Co-Chair
Thomas E Spratt, Committee Member
Richard James Courtney, Committee Member
Bruce A Stanley, Special Member

Open Access

Author:: Haakenson, Jeremy Kenneth
Title:: The Role of Ceramide in Metastatic Processes in Breast Cancer
Graduate Program:: Cell and Molecular Biology
Keywords:: ceramide
anoikis
metastasis
breast cancer
CD44
extravasation
carcinoma
epithelial-mesenchymal transition
File:: Download FINAL_FINAL.pdf
Committee Members:: Mark Kester, Dissertation Advisor/Co-Advisor
Mark Kester, Committee Chair/Co-Chair
Andrea Manni, Dissertation Advisor/Co-Advisor
Andrea Manni, Committee Chair/Co-Chair
Gary Alan Clawson, Committee Member
Cheng Dong, Committee Member
Rosalyn Bryson Irby, Committee Member

Open Access

Author:: Pang, Min
Title:: Down-regulation of H-ferritin in Glioma
Graduate Program:: Integrative Biosciences
Keywords:: Glioma
radiosensitization
H-ferritin
iron metabolism
glioma stem cells
liposomes
File:: Download 1-Thesis-Min_Pang.pdf
Committee Members:: James Robert Connor, Dissertation Advisor/Co-Advisor
James Robert Connor, Committee Chair/Co-Chair
Thomas E Spratt, Committee Member
Rosalyn Bryson Irby, Committee Member
Richard Bernard Mailman, Special Member

Open Access

Author:: Karelia, Deepkamal Nilkamal
Title:: DISCOVERY OF NOVEL Se-ASPIRIN MOLECULES AS POTENTIAL THERAPEUTICS FOR GASTROINTESTINAL CANCERS
Graduate Program:: Molecular Toxicology
Keywords:: Pancreatic cancer
colorectal cancer
small molecule
NSAIDs
apoptotsis
inflammatory pathways
selenium
aspirin
cell cycle
MTT
EMSA
Panc-1
File:: Download Final.pdf
Committee Members:: Arun Kumar Sharma, Dissertation Advisor/Co-Advisor
Arun Kumar Sharma, Committee Chair/Co-Chair
Shantu G Amin, Committee Member
Jong Kak Yun, Committee Member
Victor J Ruiz-Velasco, Outside Member
Rosalyn Bryson Irby, Committee Member

Open Access

Author:: Hernandez Borrero, Liz Janice
Title:: Anti-tumor effect and destabilization of mutant p53 by CB002, a p53-pathway restoring small molecule that stimulates autophagy
Graduate Program:: Biomedical Sciences
Keywords:: mutant p53
apoptosis
autophagy
p53 pathway restoration
small molecules
NOXA
File:: Download Masters_thesis_Liz_H._2016.pdf
Committee Members:: Wafik El-Deiry, Thesis Advisor/Co-Advisor
Scot R Kimball, Committee Member
Lisa M Shantz, Committee Member
Rosalyn Bryson Irby, Committee Member

Open Access

Author:: Nguyen, Jeffrey Quoc-Hung
Title:: INVESTIGATING THE FUNCTION AND REGULATION OF PROSTATE APOPTOSIS RESPONSE-4 IN CANCER
Graduate Program:: Molecular Medicine
Keywords:: Par-4
colon cancer
pancreatic cancer
glioblastoma
Trim21
migration
invasion
ubiquitination
proteasome
ISC-4
File:: Download Final_Dissertation_Revisions_12-01-2016.pdf
Committee Members:: Rosalyn Bryson Irby, Dissertation Advisor/Co-Advisor
Rosalyn Bryson Irby, Committee Chair/Co-Chair
Jennifer Baccon, Committee Member
Arun Kumar Sharma, Committee Member
Robert G Levenson, Outside Member

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