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Author:

Saunders, Allison Hoover

Title:

Investigation of the Structure, Function, and Regulation of Quinolinate Synthase: the Iron-Sulfur Cluster Enzyme Involved in Prokaryotic NAD+ Biosynthesis

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

NadA
iron-sulfur cluster
NAD
enzyme

File:

Download Saunders_Thesis.pdf

Committee Members:

Squire J Booker, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Chair/Co-Chair
Joseph M Bollinger Jr., Committee Member
Carsten Krebs, Committee Member
Ming Tien, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Tamanaha, Esta Yuuka

Title:

Showcasing two C-h bond-cleaving manifolds through mechanistic studies of isopenicillin N synthase

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

IPNS
isopenicillin N synthase
ACV
ferryl
ferric-superoxide

File:

Download Esta_Dissertation-GradSchoolFinal5-CorrectedSubmission.pdf

Committee Members:

Joseph M Bollinger Jr., Dissertation Advisor/Co-Advisor
Carsten Krebs, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Member
Ming Tien, Committee Member
Philip C. Bevilacqua, Committee Member

Author:

Mitchell, Andrew James

Title:

Structural Basis for Alternative Reaction Outcome by the Iron- and 2-oxoglutarate-dependent Oxygenases

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

metalloenzymes
x-ray crystallography
halogenation
Fe/2OG oxygenases

File:

Download mitchell_disserataion_2017.pdf

Committee Members:

Amie K. Boal, Dissertation Advisor/Co-Advisor
Wendy Hanna-Rose, Committee Chair/Co-Chair
Carsten Krebs, Committee Member
Joseph M Bollinger Jr., Committee Member
Philip C. Bevilacqua, Outside Member
Squire J Booker, Committee Member
Benjamin D Allen, Special Member