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Open Access

Author:: Fang, Cheng
Title:: Structural and Functional Modulation of Inhibitory Synapses by GODZ-mediated Palmitoylation of GABAA Receptors
Graduate Program:: Biology
Keywords:: trafficking
synaptogenesis
inhibitory synapses
palmitoylation
GABAA receptors
DHHC-CRD proteins
File:: Download Cheng_Thesis_April17.pdf
Committee Members:: Bernhard Luscher, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Gong Chen, Committee Member
Erin Elizabeth Sheets, Committee Member
Wendy Hanna Rose, Committee Member

Open Access

Author:: Chalkia, Dimitra
Title:: ORIGINS AND EVOLUTION OF THREE MULTIDOMAIN GENE FAMILIES CONCERNED WITH BASIC CELLULAR AND DEVELOPMENTAL PROCESSES IN EUKARYOTES
Graduate Program:: Biology
Keywords:: evolution
protein domain
functional divergence
formin
File:: Download Dimitra_Chalkia_PhD_Thesis.pdf
Committee Members:: Douglas Cavener, Committee Chair/Co-Chair
Masatoshi Nei, Committee Member
Jan Klein, Committee Member
Bernhard Luscher, Committee Member
Ross Cameron Hardison, Committee Member

Open Access

Author:: Alldred, Melissa J
Title:: AN INVESTIGATION OF THE DOMAINS OF THE GAMMA TWO SUBUNIT OF GABAA RECEPTORS, GEPHYRIN AND COLLYBISTIN REQUIRED FOR SYNAPTIC LOCALIZATION
Graduate Program:: Biochemistry, Microbiology, and Molecular Biology
Keywords:: GABA-A receptors
gephyrin
collybistin
synaptic localization
File:: Download Mel_PHD_thesis1.pdf
Committee Members:: Bernhard Luscher, Committee Chair/Co-Chair
Graham Hugh Thomas, Committee Member
Douglas Cavener, Committee Member
Randen Patterson, Committee Member
Benjamin Franklin Pugh, Committee Member

Open Access

Author:: Wang, Qian
Title:: REGULATION OF NEUROPEPTIDE Y EXPRESSION AND THE SYMPATHO-ADRENAL RESPONSE TO STRESS
Graduate Program:: Cell and Developmental Biology
Keywords:: neuropeptide Y
catecholamines
stress
adrenal medulla
File:: Download Qian_Wang_923512678_CDB_PhD_Dissertation_2011_Aug_Final_submission_.pdf
Committee Members:: Douglas Cavener, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Chair/Co-Chair
Matthew Whim, Committee Chair/Co-Chair
Bernhard Luscher, Committee Member
Melissa Rolls, Committee Member
Byron C Jones, Committee Member

Open Access

Author:: Shen, Qiuying
Title:: INVESTIGATION OF THE BRAIN SUBSTRATES OF ANXIOUS DEPRESSION
Graduate Program:: Biochemistry, Microbiology, and Molecular Biology
Keywords:: HPA axis
GABA
anxious depression
critical period
File:: Download Qiuying_thesis_0714.pdf
Committee Members:: Bernhard Luscher, Dissertation Advisor/Co-Advisor
Bernhard Luscher, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Wendy Hanna Rose, Committee Member
Debashis Ghosh, Committee Member
Jeffrey Maurice Peters, Committee Member
Robert Paulson, Committee Member

Open Access

Author:: Yuan, Xu
Title:: STRUCTURAL AND FUNCTIONAL ANALYSES OF A NOVEL INTERACTION BETWEEN GABA-A RECEPTORS AND CAML
Graduate Program:: Genetics
Keywords:: calcium modulating cyclophilin ligand
trafficking
GABA-A receptor
File:: Download xu_yuan_thesis.PDF
Committee Members:: Richard W Ordway, Committee Chair/Co-Chair
Bernhard Luscher, Committee Member
Gong Chen, Committee Member
Douglas Cavener, Committee Member
Pamela Hankey Giblin, Committee Member

Open Access

Author:: LI, YULIN
Title:: The growth retardation and liver dysfunction of PERK knockout mice
Graduate Program:: Genetics
Keywords:: PERK
Liver dysfunction
Steatosis
Wolcott-Rallison syndrome
growth retardation
EIF2AK3
File:: Download Thesis-YULIN--format_review.pdf
Committee Members:: Douglas Cavener, Committee Member
Gong Chen, Committee Member
Bernhard Luscher, Committee Chair/Co-Chair
Richard W Ordway, Committee Member
Robert Paulson, Committee Member

Open Access

Author:: Tang, Xin
Title:: Use of Human induced-pluripotent Stem Cells to Understand Molecular Mechanisms of Autism
Graduate Program:: Biology
Keywords:: Human iPSC
astrocyte
neuron
functional maturation
synapse
KCC2
GABA functional switch
MeCP2
REST
Rett syndrome
Autism
File:: Download Xin_Tang_Dissertation_The_Final_Version_20140409.pdf
Committee Members:: Gong Chen, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Chair/Co-Chair
Bernhard Luscher, Committee Member
Melissa Rolls, Committee Member
Yingwei Mao, Committee Member

Open Access

Author:: Ren, Zhen
Title:: Homeostatic control of glutamate receptor expression by GABAergic deficits and ketamine
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: Major depressive disorder (MDD)
ketamine
glutamate receptors
GABAA receptors
homeostatic adaptation
File:: Download 1-Thesis__Zhen_Ren_final.pdf
Committee Members:: Bernhard Luscher, Dissertation Advisor/Co-Advisor
Bernhard Luscher, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Douglas Cavener, Committee Member
Timothy J Jegla, Committee Member
Pamela Hankey Giblin, Committee Member

Restricted

Author:: Wang, Yue
Title:: MECHANISTIC STUDY OF ALZHEIMER’S DISEASE AND NEUROD1-MEDIATED IN VIVO CELL CONVERSION
Graduate Program:: Molecular, Cellular and Integrative Biosciences
Keywords:: Alzheimer's disease
NeuroD1
Cell conversion
Beneficial effect
GAD67
Haploinsufficiency
Small molecule cocktail
Therapy
In vivo
File:: No files available due to restrictions.
Committee Members:: Gong Chen, Dissertation Advisor/Co-Advisor
Douglas Cavener, Committee Chair/Co-Chair
Bernhard Luscher, Committee Member
Kevin Douglas Alloway, Committee Member
Yingwei Mao, Outside Member

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