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Author:

Weiner, Alexis

Title:

Dendritic Microtubule Polarity is Maintained by Kinesin-2 Steering and Positioning of Nucleation Sites by Endosomal Wnt Signaling Proteins

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

neurons
microtubules
nucleation
APC2
gTub
dendrite

File:

Download Dissertation_AW.pdf

Committee Members:

Melissa Rolls, Dissertation Advisor/Co-Advisor
Melissa Rolls, Committee Chair/Co-Chair
Timothy J Jegla, Committee Member
Lorraine C Santy, Committee Member
William O Hancock, Outside Member
Melissa Rolls, Program Head/Chair

Author:

Feng, Qingzhou

Title:

Motor dynamics underling bidirectional cargo transport by kinesin and dynein

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

kinesin
dynein
microtubule
bidirectional transport

File:

Download Thesis_May2020QF.pdf

Committee Members:

William O Hancock, Dissertation Advisor/Co-Advisor
Melissa Rolls, Committee Member
Lu Bai, Committee Member
Charles T Anderson, Committee Member
Christopher Martin Yengo, Outside Member
Melissa Rolls, Program Head/Chair
William O. Hancock, Committee Chair/Co-Chair

Author:

Radford, Thomas

Title:

Differentiation of mesenchymal stem cells to tendon-like progenitor cells via growth factor stimulation

Graduate Program:

Bioengineering

Keywords:

GDF7
mesenchymal stem cells
tenocyte differentiation
scleraxis
runx2

File:

Download Tom_Radford_master_thesis_final_draft_1.2.pdf

Committee Members:

Justin L. Brown, Thesis Advisor/Co-Advisor
William O Hancock, Committee Member
Spencer Szczesny, Committee Member
William O Hancock, Program Head/Chair

Author:

Carrozzi, Sabrina

Title:

Development of an in vitro culture and loading protocol to study the mechanobiology of rabbit anterior cruciate ligaments

Graduate Program:

Biomedical Engineering

Keywords:

anterior cruciate ligament
ACL
mechanobiology
ligament
tendon
allograft
autograft
biomechanics

File:

Download Final_Master_s_Thesis.pdf

Committee Members:

Spencer Szczesny, Thesis Advisor/Co-Advisor
William O Hancock, Committee Member
John Vairo, Committee Member
Cheng Dong, Program Head/Chair

Author:

Mc Ilroy, Kyle

Title:

MODELING SERUM-DRUG KINETICS FOR THE PREDICTION OF CANCER RESISTANCE TO SECOND LINE THERAPEUTICS

Graduate Program:

Bioengineering

Keywords:

cancer

File:

Download KyleChristopherMcIlroy_MastersThesis.pdf

Committee Members:

Justin R Pritchard, Thesis Advisor/Co-Advisor
William O Hancock, Program Head/Chair
Deb Kelly, Committee Member
William O Hancock, Committee Member

Author:

Feng, Chengye

Title:

Investigation of microtubule polarity regulation in dendrites of drosophila sensory neurons

Graduate Program:

Molecular, Cellular and Integrative Biosciences

Keywords:

microtubule polarity
Patronin
Trim9
kinesin-5
dendrite development
dynamic instability

File:

Download Thesis_draft_Chengye_Feng_Spring_2020_final.pdf

Committee Members:

Melissa Rolls, Dissertation Advisor/Co-Advisor
Melissa Rolls, Committee Chair/Co-Chair
Yingwei Mao, Committee Member
Richard W Ordway, Committee Member
William O Hancock, Outside Member
Melissa Rolls, Program Head/Chair

Author:

Haselden, William

Title:

Spatial and temporal patterns of nitric oxide diffusion and degradation drive emergent cerebrovascular dynamics

Graduate Program:

Neuroscience

Keywords:

nitric oxide
neurovascular coupling
vasomotion
computational model
hemoglobin
hemodynamics

File:

Download Dissertation_in_Neuroscience_-_Haselden.pdf

Committee Members:

Patrick James Drew, Dissertation Advisor/Co-Advisor
Patrick James Drew, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Kevin Douglas Alloway, Committee Member
William O Hancock, Outside Member
Kevin Douglas Alloway, Program Head/Chair

Author:

Houtz, Brady

Title:

A Study of the Effect of Hematocrit on an Elevated Beat Rate in the 12cc Penn State Pediatric Ventricular Assist Device

Graduate Program:

Bioengineering

Keywords:

artificial heart
pediatric
hematocrit
ventricular assist device
cardiovascular fluid dynamics
elevated beat rate

File:

Download Houtz_MastersThesis.pdf

Committee Members:

Keefe B Manning, Thesis Advisor/Co-Advisor
William Joseph Weiss, Committee Member
William Hancock, Committee Member
William O Hancock, Program Head/Chair

Author:

Deal, Jack

Title:

Modeling the Dynamics of Elk Subfamily Ion Channels for Physiological Modulation

Graduate Program:

Bioengineering

Keywords:

Elk
Voltage-gated ion channels
Potassium channels
Drosophila melanogaster
Xenopus
Kinetic model
Fluorescent Microscopy
Ankyrin
Axon Initial Segment
Boltzmann
Heme

File:

Download MODELING_THE_DYNAMICS_OF_ELK_SUBFAMILY_ION_CHANNELS_FOR_PHYSIOLOGICAL_MODULATION.pdf

Committee Members:

Timothy J Jegla, Thesis Advisor/Co-Advisor
William O Hancock, Program Head/Chair
William O Hancock, Committee Member
Justin Lee Brown, Committee Member

Author:

Manzano Garcia, Jesus

Title:

Therapeutic grade RNA purification by ultrafiltration

Graduate Program:

Chemical Engineering

Keywords:

Nucleic Acids
Purification
Ultrafiltration

File:

Download Ivan_Manzano-Dissertation_rev.pdf

Committee Members:

Andrew Zydney, Dissertation Advisor/Co-Advisor
Andrew Zydney, Committee Chair/Co-Chair
Themis Matsoukas, Committee Member
Hee Jeung Oh, Committee Member
William O Hancock, Outside Member
Phillip E Savage, Program Head/Chair