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Author:

Geathers, Jasmine

Title:

Development of a Rapid and Clinically Relevant Model of AMD

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Hyperreflective Foci
AMD
R345W fibulin-3
Sodium Iodate
Retinal Degeneration

File:

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Committee Members:

Salvatore Stella, Major Field Member
Ralph Keil, Program Head/Chair
John Hulleman, Special Member
Vladimir Spiegelman, Outside Unit & Field Member
Jeffrey Sundstrom, Chair & Dissertation Advisor
James Connor, Dissertation Co-Advisor

Author:

Bricker, Kristen

Title:

MIR-21 REGULATION OF SYSTEMIC AUTOIMMUNITY AND IMMUNITY

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

B cells
Autoimmunity
Germinal Center
Antibody
Infection
Influenza
Plasma Cells
miRNA

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Committee Members:

Aron Lukacher, Major Field Member
Ziaur Rahman, Chair & Dissertation Advisor
Todd Schell, Major Field Member
Zissis Chroneos, Outside Unit & Field Member
Ralph Keil, Program Head/Chair
Aron Eliot Lukacher, Special Member
S. Rameeza Allie, Major Field Member

Author:

Shenoy, Ganesh

Title:

The Role of Iron in Glioblastoma

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

glioblastoma
iron

File:

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Committee Members:

Jeffrey Sundstrom, Outside Unit & Field Member
James Connor, Chair & Dissertation Advisor
Todd Schell, Major Field Member
Zissis Chroneos, Major Field Member
Ralph Keil, Program Head/Chair
Sheldon Holder, Special Member

Author:

Crawford, Lataijah

Title:

Characterization Of Decursinol Efficacy, Tolerance, And Mechanism In Models Of Pain

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

AGN; Angelica gigas Nakai
DOH; Decursinol
CENP; Chemotherapy-evoked neuropathic pain
MOR; Morphine
NXO; Naloxone
TRPA1; Transient receptor potential ankyrin 1
TRPV1
Transient receptor vanilloid receptor 1
TRPV1; Transient receptor vanilloid receptor 1
5-HT2; Serotonin receptor 2
5-HT2A; Serotonin receptor 2A
5-HT2C; Serotonin receptor 2C
CB1; Cannabinoid receptor type 1
CB2; Cannabinoid receptor type 2
WT; Wild-type mouse

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Committee Members:

Junxuan Lu, Outside Field Member
Patricia Grigson Kennedy, Outside Unit Member
Ralph Keil, Program Head/Chair
John Ellis, Major Field Member
Daniel Morgan, Special Member
Lisa Shantz, Chair & Dissertation Advisor

Author:

Baringer, Stephanie

Title:

Regulation of Brain Iron Acquisition and Misappropriation in Alzheimer's Disease

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

blood-brain barrier
iron
transferrin
Alzheimer's disease

File:

Download SBaringer_Dissertation_Final_post_defense.pdf

Committee Members:

Xuemei Huang, Major Field Member
David Degraff, Outside Field Member
Elizabeth Proctor, Major Field Member
Yongsoo Kim, Outside Unit Member
James Connor, Chair & Dissertation Advisor
Ralph Keil, Program Head/Chair

Author:

Stein, MaryElizabeth

Title:

G-Quadruplexes and Inflammation: A Tale of Two Paradoxes Challenging Genome Stability and the Response of Two Specialized Polymerases

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Genome instability
DNA replication
non-B DNA
G-quadruplexes
DNA polymerase δ
DNA polymerase η
DNA polymerase κ
Chronic inflammation
Ulcerative colitis

File:

Download Stein_Thesis_FINAL.pdf

Committee Members:

Neil Christensen, Major Field Member
Gregory Yochum, Major Field Member
Amanda Nelson, Major Field Member
Kristin Eckert, Chair & Dissertation Advisor
Lisa M Shantz, Program Head/Chair
Lisa Shantz, Outside Unit & Field Member

Author:

Fleeman, Rebecca

Title:

Alzheimer’s Disease Risk Conveyed by Apolipoprotein E ε4: Immunometabolism and the Brain-Body Connection

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

immunometabolism
alzheimer's disease
APOE4
cytokine signaling
multivariate modeling
neurodegeneration
aging
astrocytes
neurons

File:

Download Fleeman_Dissertation_2023.pdf

Committee Members:

Richard Mailman, Outside Field Member
Elizabeth Proctor, Co-Chair & Dissertation Advisor
Yongsoo Kim, Major Field Member
Amy Arnold, Outside Unit Member
Ralph Keil, Program Head/Chair
Kent Vrana, Co-Chair of Committee

Author:

Liu, Xiaoming

Title:

Mechanisms of resistance to anti-GD2 immunotherapy in neuroblastoma

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Neuroblastoma
Small extracellular vesicles
Tumor microenvironment
NK cells
anti-GD2 immunotherapy
CRISPR screen

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Committee Members:

Vladimir Spiegelman, Major Field Member
Jeffrey Sundstrom, Outside Unit Member
Hong-Gang Wang, Chair & Dissertation Advisor
Todd Schell, Major Field Member
Edward Harhaj, Outside Field Member
Ralph Keil, Program Head/Chair

Author:

Walston, Joshua

Title:

Epstein-Barr virus Glycoproteins BDLF2 and BMRF2 are Important for Efficient Infection and Spread in Oral Epithelia

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

EBV
BDLF2
BMRF2
Cell-to-cell
Stratified Epithelium
Herpesvirus

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Committee Members:

Ralph Keil, Program Head/Chair
Neil Christensen, Major Field Member
Gregory Yochum, Outside Unit & Field Member
Jianming Hu, Major Field Member
Jeffery Sample, Major Field Member
Clare Sample, Chair & Dissertation Advisor

Author:

Hayman, Ian

Title:

Infection and Intercellular Spread of Epstein-Barr Virus in Stratified Epithelium

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Epstein-Barr virus
EBV
intercellular spread
epithelial infection
initial site of infection
persistence
latency
BDLF2
entry

File:

Download IanHayman_Dissertation_FinalSubmission.pdf

Committee Members:

Jianming Hu, Major Field Member
Nicholas Buchkovich, Major Field Member
Charles Lang, Outside Unit & Field Member
Clare Sample, Chair & Dissertation Advisor
Ralph Keil, Program Head/Chair