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Start Over Degree PHD Year 2018 Committee Member William O Hancock

1. Coupled biophysical simulations of cell-cell interaction and drug delivery microrobots

open_access
Open Access
Author:
Gaskin, Byron Jerrod
Title:
Coupled biophysical simulations of cell-cell interaction and drug delivery microrobots
Graduate Program:
Bioengineering
Keywords:
computational mechanics
personalized medicine
computational fluid dynamics
computational structural mechanics
biochemistry
fluid dynamics
solid mechanics
continuum mechanics
blood flow
blood cells
drug delivery
drug targeting
microrobotics
flowing bodies
hyperelasticity
rigid body motion
File:
Download BJG_PhD_Final.pdf
Committee Members:
Robert Francis Kunz, Dissertation Advisor/Co-Advisor
Robert Francis Kunz, Committee Chair/Co-Chair
Cheng Dong, Committee Member
William O Hancock, Committee Member
Robert Lee Campbell, Outside Member
Sean Michael Mcintyre, Special Member

2. THE ROLE OF THE MEMBRANE IN INTEGRIN-MEDIATED ADHESION OF CELLS TO SURFACES

open_access
Open Access
Author:
Son, Seoyoung
Title:
THE ROLE OF THE MEMBRANE IN INTEGRIN-MEDIATED ADHESION OF CELLS TO SURFACES
Graduate Program:
Bioengineering
Keywords:
Integrin
Membrane mechanical Properties
Time-correlated single photon microscopy
Cell adhesion
Fluorescence correlation spectroscopy
Optical trap
File:
Download Dissertation_Final.pdf
Committee Members:
Peter J Butler, Dissertation Advisor/Co-Advisor
Peter J Butler, Committee Chair/Co-Chair
William O Hancock, Committee Member
Justin Lee Brown, Committee Member
Tae-Hee Lee, Outside Member
Esther Winter Gomez, Committee Member

3. IN VITRO STUDIES OF CLASS B METHYLASES, AN ELUSIVE CLASS OF COBALAMIN-DEPENDENT RADICAL SAM ENZYMES

open_access
Open Access
Author:
Blaszczyk, Anthony J
Title:
IN VITRO STUDIES OF CLASS B METHYLASES, AN ELUSIVE CLASS OF COBALAMIN-DEPENDENT RADICAL SAM ENZYMES
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
enzyme
cobalamin
s-adenosylmethionine
radical sam
protein purification
biochemistry
mechanistic enzymology
methylation
Class B methylase
TsrM
Fom3
PhpK
File:
Download Thesis_Blaszczyk_Final_II.docx.pdf
Committee Members:
Squire J Booker, Dissertation Advisor/Co-Advisor
Squire J Booker, Committee Chair/Co-Chair
Carsten Krebs, Committee Member
Joseph M Bollinger Jr., Committee Member
William O Hancock, Outside Member
Amie Kathleen Boal, Committee Member

5. CELL-CELL INTERACTIONS IN THE TUMOR MICROENVIRONMENT: OVERCOMING THE ENDOTHELIAL BARRIER FOR TARGETED DRUG DELIVERY STRATEGIES

open_access
Open Access
Author:
Aragon Sanabria, Virginia
Title:
CELL-CELL INTERACTIONS IN THE TUMOR MICROENVIRONMENT: OVERCOMING THE ENDOTHELIAL BARRIER FOR TARGETED DRUG DELIVERY STRATEGIES
Graduate Program:
Biomedical Engineering
Keywords:
Endothelial cells
Gap formation
Tumor Microenvironment
Nanoparticles
Immune-mediated therapy
Metastasis
Cell-cell interactions
File:
Download VAS_-_Final_Thesis.pdf
Committee Members:
Cheng Dong, Dissertation Advisor/Co-Advisor
Cheng Dong, Committee Chair/Co-Chair
Esther Winter Gomez, Committee Member
William O Hancock, Committee Member
Andrea M. Mastro, Outside Member

6. CONTRIBUTION OF KINESIN-MEDIATED MICROTUBULE DYNAMICS TO THE REGULATION OF MITOTIC SPINDLE STABILITY: MOLECULAR MECHANISM OF KINESIN-MICROTUBULE INTERACTION

open_access
Open Access
Author:
Chen, Geng Yuan
Title:
CONTRIBUTION OF KINESIN-MEDIATED MICROTUBULE DYNAMICS TO THE REGULATION OF MITOTIC SPINDLE STABILITY: MOLECULAR MECHANISM OF KINESIN-MICROTUBULE INTERACTION
Graduate Program:
Bioengineering
Keywords:
Kinesin
Microtubule
Microtubule-associated protein
Eg5 inhibitors
Mitosis
Size-scaling problem
Single-molecule
transient kinetics
Tubulin dynamics
File:
Download _20180720__Geng-Yuan_Chen_Dissertation.pdf
Committee Members:
William O Hancock, Dissertation Advisor/Co-Advisor
William O Hancock, Committee Chair/Co-Chair
Peter J Butler, Committee Member
Justin Lee Brown, Committee Member
Melissa Rolls, Outside Member

7. Structure-Function Relationships and Biochemical Manipulation of 6-TM Superfamily Ion Channels

open_access
Open Access
Author:
Pisupati, Aditya
Title:
Structure-Function Relationships and Biochemical Manipulation of 6-TM Superfamily Ion Channels
Graduate Program:
Neuroscience
Keywords:
ion channels
voltage-gated
structure
function
six-transmembrane
6-TM
Shaker
CNBD
TRPV
File:
Download AP_Thesis_Final.pdf
Committee Members:
Timothy J Jegla, Dissertation Advisor/Co-Advisor
Timothy J Jegla, Committee Chair/Co-Chair
Melissa Rolls, Committee Member
Bernhard Luscher, Committee Member
William O Hancock, Outside Member
Santhosh Girirajan, Committee Member

8. Gene Regulation By Divergent Gene Pairs and Nucleosome Depleting Factors

open_access
Open Access
Author:
Yan, Chao
Title:
Gene Regulation By Divergent Gene Pairs and Nucleosome Depleting Factors
Graduate Program:
Biochemistry, Microbiology, and Molecular Biology
Keywords:
Nucleosome depleting factors
divergent gene pairs
divergent transcription
transcription
gene regulation
File:
Download 1810_Thesis_Draft_Chao_final.pdf
Committee Members:
Lu Bai, Dissertation Advisor/Co-Advisor
Lu Bai, Committee Chair/Co-Chair
Joseph C. Reese, Committee Member
Benjamin Franklin Pugh, Committee Member
William O Hancock, Outside Member
Shaun A Mahony, Committee Member